PROCESS FOR THE PURIFICATION OF TERBINAFINE

PROCESS FOR THE PURIFICATION OF TERBINAFINE

PURIFICATION PROCESS Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula (I), in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 1000C and reduced pressure...

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Hauptverfasser: PENN, GERHARD, BEUTLER, ULRICH
Format: Patent
Sprache:eng
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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creator PENN, GERHARD
BEUTLER, ULRICH
description PURIFICATION PROCESS Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula (I), in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e.g. at a temperature above 1000C and reduced pressure, e.g. 0.2 mbar, and recovering the purified product in free base or acid addition salt form.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR THE PURIFICATION OF TERBINAFINE
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