OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF

Among other things, the present disclosure provides RHO oligonucleotides, compositions, and methods. In some embodiments, provided oligonucleotides comprise nucleobase modifications, sugar modifications, internucleotidic linkage modifications and/or patterns thereof, and have improved properties, ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: IWAMOTO, Naoki, VATHIPADIEKAL, Vinod, BYRNE, Michael John, GUO, Lankai, VARGEESE, Chandra, HOSS, Andrew Guzior
Format: Patent
Sprache:eng
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