GPRC5D CHIMERIC ANTIGEN RECEPTORS AND CELLS EXPRESSING THE SAME

The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.

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Hauptverfasser: SINGH, Sanjaya, VENKATARAMANI, Sathya, HEIDRICH, Bradley J, LI, Yingzhe, ATTAR, Ricardo, LEE, John, GANESAN, Rajkumar, GAUDET, Francois, JONES, Carmen Baca
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creator SINGH, Sanjaya
VENKATARAMANI, Sathya
HEIDRICH, Bradley J
LI, Yingzhe
ATTAR, Ricardo
LEE, John
GANESAN, Rajkumar
GAUDET, Francois
JONES, Carmen Baca
description The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title GPRC5D CHIMERIC ANTIGEN RECEPTORS AND CELLS EXPRESSING THE SAME
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