IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS
The invention provides certain difluorocyclohexyl-imidazopyridazinyl-imidazolidinone compounds of formula II as IL-17A inhibitors, pharmaceutical compositions thereof, and methods of using a compound of formula II to treat certain symptoms of psoriasis, rheumatoid arthritis or multiple sclerosis.
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| creator | COATES, David Andrew WOODMAN, Michael Edward HOLLOWAY, William Glen RICHETT, Michael Enrico FRIMPONG, Kwame JONES, Spencer Brian LUGAR, Charles Willis III LEVINSON, Adam Marc WATSON, Brian Morgan |
| description | The invention provides certain difluorocyclohexyl-imidazopyridazinyl-imidazolidinone compounds of formula II as IL-17A inhibitors, pharmaceutical compositions thereof, and methods of using a compound of formula II to treat certain symptoms of psoriasis, rheumatoid arthritis or multiple sclerosis. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS |
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