OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to methods of using compounds formula I:and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutic...

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Hauptverfasser: VILLEMURE, Elisia, CHEN, Huifen, LAROUCHE-GAUTHIER, Robin, TERRETT, Jack Alexander, BEAUMIER, Francis, VOLGRAF, Matthew, CONSTANTINEAU-FORGET, Lea, GRAND-MAÎTRE, Chantal, LÉPISSIER, Luce, DÉRY, Martin, STURINO, Claudio
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creator VILLEMURE, Elisia
CHEN, Huifen
LAROUCHE-GAUTHIER, Robin
TERRETT, Jack Alexander
BEAUMIER, Francis
VOLGRAF, Matthew
CONSTANTINEAU-FORGET, Lea
GRAND-MAÎTRE, Chantal
LÉPISSIER, Luce
DÉRY, Martin
STURINO, Claudio
description The invention relates to methods of using compounds formula I:and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
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In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS
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