METHODS OF MANUFACTURE OF NUT FLOURS AND FORMULATIONS FOR ORAL IMMUNOTHERAPY

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 19 July 2018 (19.07.2018) WIP0 1 PCT omitia °nolo 011101110100111H 0111111 oimIE (10) International Publication Number WO 2018/132733 Al (51) International Patent Classification: A23L 5/20 (2016.01) A23L 7/10 (2016.01) (21) International Application Number: PCT/US2018/013612 (22) International Filing Date: 12 January 2018 (12.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/446,147 13 January 2017 (13.01.2017) US (71) Applicant: AIMMUNE THERAPEUTICS, INC. [US/US]; 8000 Marina Boulevard, Suite 200, Brisbane, CA 94005-1884 (US). (72) Inventors: SIMON, Reyna, Joy; c/o Aimmune Therapeu- tics, Inc., 8000 Marina Boulevard, Suite 200, Brisbane, CA 94005-1884 (US). BIRRINGER, Nicholas, William; c/o Aimmune Therapeutics, Inc., 8000 Marina Boulevard, Suite 200, Brisbane, CA 94005-1884 (US). (74) Agent: WEINER, Ethan, M. et al.; Morrison & Foerster LLP, 755 Page Mill Road, Palo Alto, CA 94304-1018 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: - with international search report (Art. 21(3)) - before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) 11 N 11 00 11 O C (54) Title: METHODS OF MANUFACTURE OF NUT FLOURS AND FORMULATIONS FOR ORAL IMMUNOTHERAPY (57) : The pr