ANTIMICROBIAL CATIONIC POLYCARBONATES

Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end grou...

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Hauptverfasser: NG, VICTOR W.L, ONG, ZHAN-YUIN, YANG, YI YAN, COADY, DANIEL JOSEPH, DIPIETRO, RICHARD ANTHONY, HEDRICK, JAMES LUPTON, TAN, JEREMY P.K, ENGLER, AMANDA CATHERINE
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creator NG, VICTOR W.L
ONG, ZHAN-YUIN
YANG, YI YAN
COADY, DANIEL JOSEPH
DIPIETRO, RICHARD ANTHONY
HEDRICK, JAMES LUPTON
TAN, JEREMY P.K
ENGLER, AMANDA CATHERINE
description Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ANTIMICROBIAL CATIONIC POLYCARBONATES
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