MONOCLONAL ANTIBODIES TARGETING NEUTRALIZING EPITOPES ON H7 INFLUENZA VIRUSES

The present invention relates to the murine monoclonal antibody (mAb) 11B9 which targets major neutralizing epitopes of influenza A H7 hemagglutinin and active fragments thereof. The present invention also relates to methods and compositions for the prophylaxis and treatment of H7 influenza using mu...

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Hauptverfasser: HE, FANG, SUBASCHANDRABOSE, RAJESH KUMAR, KWANG, HWEI-SING, JIMMY
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creator HE, FANG
SUBASCHANDRABOSE, RAJESH KUMAR
KWANG, HWEI-SING, JIMMY
description The present invention relates to the murine monoclonal antibody (mAb) 11B9 which targets major neutralizing epitopes of influenza A H7 hemagglutinin and active fragments thereof. The present invention also relates to methods and compositions for the prophylaxis and treatment of H7 influenza using murine mAb 11B9 or fragments thereof. The present invention further relates to methods and kits for determining, identifying and/or quantifying (a) influenza A hemagglutinin in a sample or vaccine or (b) an antibody against influenza A hemagglutinin.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title MONOCLONAL ANTIBODIES TARGETING NEUTRALIZING EPITOPES ON H7 INFLUENZA VIRUSES
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