FUSION PROTEINS TO FACILITATE SELECTION OF CELLS INFECTED WITH SPECIFIC IMMUNOGLOBULIN GENE RECOMBINANT VACCINIA VIRUS
The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eu...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | PARIS, MARK SMITH, ERNEST, S PANDINA, TRACY CROY, LESLIE, A KIRK, RENEE MOKSA, ANGELIKA ZAUDERER, MAURICE |
| description | The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_SG11201406974YA</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>SG11201406974YA</sourcerecordid><originalsourceid>FETCH-epo_espacenet_SG11201406974YA3</originalsourceid><addsrcrecordid>eNqNyrEKwjAQgOEuDqK-ww2uQqtFcUzPS3uQXqRJKk6lSJxECxWfXwUfwOmHn2-avHRwbAWOjfXE4sBb0ArZsFeewJEh9F9gNSAZ44BFfxYd4MS-AnckZM0IXNdBbGlsEQwLlCQEDaGtCxYlHlqFyMIKWm6CmyeTa38b4-LXWbLU5LFaxeHRxXHoL_Een50rs2ydZnm63e_ys9r8yd6k_Ts5</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>FUSION PROTEINS TO FACILITATE SELECTION OF CELLS INFECTED WITH SPECIFIC IMMUNOGLOBULIN GENE RECOMBINANT VACCINIA VIRUS</title><source>esp@cenet</source><creator>PARIS, MARK ; SMITH, ERNEST, S ; PANDINA, TRACY ; CROY, LESLIE, A ; KIRK, RENEE ; MOKSA, ANGELIKA ; ZAUDERER, MAURICE</creator><creatorcontrib>PARIS, MARK ; SMITH, ERNEST, S ; PANDINA, TRACY ; CROY, LESLIE, A ; KIRK, RENEE ; MOKSA, ANGELIKA ; ZAUDERER, MAURICE</creatorcontrib><description>The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141127&DB=EPODOC&CC=SG&NR=11201406974YA$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141127&DB=EPODOC&CC=SG&NR=11201406974YA$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PARIS, MARK</creatorcontrib><creatorcontrib>SMITH, ERNEST, S</creatorcontrib><creatorcontrib>PANDINA, TRACY</creatorcontrib><creatorcontrib>CROY, LESLIE, A</creatorcontrib><creatorcontrib>KIRK, RENEE</creatorcontrib><creatorcontrib>MOKSA, ANGELIKA</creatorcontrib><creatorcontrib>ZAUDERER, MAURICE</creatorcontrib><title>FUSION PROTEINS TO FACILITATE SELECTION OF CELLS INFECTED WITH SPECIFIC IMMUNOGLOBULIN GENE RECOMBINANT VACCINIA VIRUS</title><description>The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEuDqK-ww2uQqtFcUzPS3uQXqRJKk6lSJxECxWfXwUfwOmHn2-avHRwbAWOjfXE4sBb0ArZsFeewJEh9F9gNSAZ44BFfxYd4MS-AnckZM0IXNdBbGlsEQwLlCQEDaGtCxYlHlqFyMIKWm6CmyeTa38b4-LXWbLU5LFaxeHRxXHoL_Een50rs2ydZnm63e_ys9r8yd6k_Ts5</recordid><startdate>20141127</startdate><enddate>20141127</enddate><creator>PARIS, MARK</creator><creator>SMITH, ERNEST, S</creator><creator>PANDINA, TRACY</creator><creator>CROY, LESLIE, A</creator><creator>KIRK, RENEE</creator><creator>MOKSA, ANGELIKA</creator><creator>ZAUDERER, MAURICE</creator><scope>EVB</scope></search><sort><creationdate>20141127</creationdate><title>FUSION PROTEINS TO FACILITATE SELECTION OF CELLS INFECTED WITH SPECIFIC IMMUNOGLOBULIN GENE RECOMBINANT VACCINIA VIRUS</title><author>PARIS, MARK ; SMITH, ERNEST, S ; PANDINA, TRACY ; CROY, LESLIE, A ; KIRK, RENEE ; MOKSA, ANGELIKA ; ZAUDERER, MAURICE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SG11201406974YA3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2014</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PARIS, MARK</creatorcontrib><creatorcontrib>SMITH, ERNEST, S</creatorcontrib><creatorcontrib>PANDINA, TRACY</creatorcontrib><creatorcontrib>CROY, LESLIE, A</creatorcontrib><creatorcontrib>KIRK, RENEE</creatorcontrib><creatorcontrib>MOKSA, ANGELIKA</creatorcontrib><creatorcontrib>ZAUDERER, MAURICE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PARIS, MARK</au><au>SMITH, ERNEST, S</au><au>PANDINA, TRACY</au><au>CROY, LESLIE, A</au><au>KIRK, RENEE</au><au>MOKSA, ANGELIKA</au><au>ZAUDERER, MAURICE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FUSION PROTEINS TO FACILITATE SELECTION OF CELLS INFECTED WITH SPECIFIC IMMUNOGLOBULIN GENE RECOMBINANT VACCINIA VIRUS</title><date>2014-11-27</date><risdate>2014</risdate><abstract>The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_SG11201406974YA |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | FUSION PROTEINS TO FACILITATE SELECTION OF CELLS INFECTED WITH SPECIFIC IMMUNOGLOBULIN GENE RECOMBINANT VACCINIA VIRUS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T17%3A22%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PARIS,%20MARK&rft.date=2014-11-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ESG11201406974YA%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |