MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR The present invention features a compound of formula (I): (I) or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic...

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Hauptverfasser: KHATUYA, Haripada, JOSHI, Pramod Virupax, HADIDA-RUAH, Sara Sabina, MCCARTNEY, Jason, CLEVELAND, Thomas, GROSS, Raymond Stanley, SILINA, Alina, MARELIUS, Gulin Erdogan, PIERRE, Fabrice Jean Denis, KRENITSKY, Paul John, GROOTENHUIS, Peter Diederik Jan, COON, Timothy Richard, CLEMENS, Jeremy J, ZHOU, Jinglan, ANDERSON, Corey, MILLER, Mark Thomas, LIN, Chun-Chieh, ARUMUGAM, Vijayalaksmi, BINCH, Hayley Marie, FRIEMAN, Bryan A, NICHOLLS, Georgia McGaughey, TERMIN, Andreas P, BEAR, Brian Richard, UY, Johnny, MELILLO, Vito, CONROY, Erica
Format: Patent
Sprache:eng
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Zusammenfassung:MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR The present invention features a compound of formula (I): (I) or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.