HYDROXYLATED AND METHOXYLATED CYCLOPENTA [D] PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I for use in oral dosage forms: Also provided are oral dosage forms comprising these compounds, methods of using the compou...
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| creator | CHABOT, CHRISTINE BENCSIK, JOSEF ZHANG, BIRONG DO, STEVEN SCHLACHTER, STEPHEN KALLAN, NICHOLAS LIANG, JUN SPENCER, KEITH XIAO, DENGMING MITCHELL, IAN XU, RUI BLAKE, JAMES WALLACE, ELI BANKA, ANNA SAFINA, BRIAN |
| description | The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I for use in oral dosage forms: Also provided are oral dosage forms comprising these compounds, methods of using the compounds and oral dosage forms of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. Further provided are intermediate compounds from the synthesis of these compounds. |
| format | Patent |
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Further provided are intermediate compounds from the synthesis of these compounds.</abstract><oa>free_for_read</oa></addata></record> |
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| title | HYDROXYLATED AND METHOXYLATED CYCLOPENTA [D] PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS |
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