POLYSILYLERAT KANAMYCIN A ELLER B DERIVAT

POLYSILYLERAT KANAMYCIN A ELLER B DERIVAT

1-N-[ omega -amino- alpha -hydroxyalkanoyl] kanamycins A and B of the formula I in which R represents OH or NH2, are prepared by acylation of polysilylated kanamycin A or B, or polysilylated kanamycin A or B which has a protective group other than silyl on the 6'-amino group, with an acylating...

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1. Verfasser: M J CRON
Format: Patent
Sprache:swe
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CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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creator M J CRON
description 1-N-[ omega -amino- alpha -hydroxyalkanoyl] kanamycins A and B of the formula I in which R represents OH or NH2, are prepared by acylation of polysilylated kanamycin A or B, or polysilylated kanamycin A or B which has a protective group other than silyl on the 6'-amino group, with an acylating derivative of an acid of the formula II in which n is an integer from 0 to 2 and B is an amino protective group, in an essentially anhydrous organic solvent and by subsequent removal of all blocking groups. The compounds have therapeutic properties.
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The compounds have therapeutic properties.</description><language>swe</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; SUGARS</subject><creationdate>1990</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19900115&amp;DB=EPODOC&amp;CC=SE&amp;NR=461148B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19900115&amp;DB=EPODOC&amp;CC=SE&amp;NR=461148B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>M J CRON</creatorcontrib><title>POLYSILYLERAT KANAMYCIN A ELLER B DERIVAT</title><description>1-N-[ omega -amino- alpha -hydroxyalkanoyl] kanamycins A and B of the formula I in which R represents OH or NH2, are prepared by acylation of polysilylated kanamycin A or B, or polysilylated kanamycin A or B which has a protective group other than silyl on the 6'-amino group, with an acylating derivative of an acid of the formula II in which n is an integer from 0 to 2 and B is an amino protective group, in an essentially anhydrous organic solvent and by subsequent removal of all blocking groups. The compounds have therapeutic properties.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1990</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAM8PeJDPb0ifRxDXIMUfB29HP0jXT29FNwVHD1AYopOCm4uAZ5hjmG8DCwpiXmFKfyQmluBjk31xBnD93Ugvz41OKCxOTUvNSS-GBXEzNDQxMLJ2OCCgBhkyMo</recordid><startdate>19900115</startdate><enddate>19900115</enddate><creator>M J CRON</creator><scope>EVB</scope></search><sort><creationdate>19900115</creationdate><title>POLYSILYLERAT KANAMYCIN A ELLER B DERIVAT</title><author>M J CRON</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SE461148B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>swe</language><creationdate>1990</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>M J CRON</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>M J CRON</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>POLYSILYLERAT KANAMYCIN A ELLER B DERIVAT</title><date>1990-01-15</date><risdate>1990</risdate><abstract>1-N-[ omega -amino- alpha -hydroxyalkanoyl] kanamycins A and B of the formula I in which R represents OH or NH2, are prepared by acylation of polysilylated kanamycin A or B, or polysilylated kanamycin A or B which has a protective group other than silyl on the 6'-amino group, with an acylating derivative of an acid of the formula II in which n is an integer from 0 to 2 and B is an amino protective group, in an essentially anhydrous organic solvent and by subsequent removal of all blocking groups. 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subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title POLYSILYLERAT KANAMYCIN A ELLER B DERIVAT
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