NYA TRIPEPTIDER, SOM INVERKAR PA DET CENTRALA NERVSYSTEMET
The invention relates to new peptide derivatives which act on the central nervous system and correspond to the general formula (I), X-Y-W-NH2 (I) wherein X is L-pyroglutamyl, D-pyroglutamyl, L-2-keto-imidazolidine-4-carbonyl, L-6-keto-pipecolyl, L-thiazolidine-4-carbonyl, L-prolyl or orotyl group, Y...
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| creator | 4)E PALOSI 3)L BALASPIRI 2)T SZIRTES 5)L SPORNY 6)A SARKADI 1)L KISFALUDY |
| description | The invention relates to new peptide derivatives which act on the central nervous system and correspond to the general formula (I), X-Y-W-NH2 (I) wherein X is L-pyroglutamyl, D-pyroglutamyl, L-2-keto-imidazolidine-4-carbonyl, L-6-keto-pipecolyl, L-thiazolidine-4-carbonyl, L-prolyl or orotyl group, Y is L-leucyl, L-norvalyl or L-histidyl group, and W is L-prolyl, D-prolyl, L-thiazolidine-4-carbonyl, L-pipecolyl, L-homoprolyl, L-leucyl, L-isoleucyl, L-methionyl or D-pipecolyl group, or the W-NH2 group stands for pyrrolidyl or piperidyl group, with the proviso that if X is L-pyroglutamyl and Y is L-histidyl group, W is other than L-prolyl group, and pharmaceutically acceptable complexes thereof. These compounds are prepared by methods commonly applied in the peptide chemistry. |
| format | Patent |
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These compounds are prepared by methods commonly applied in the peptide chemistry.</description><edition>4</edition><language>swe</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1986</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19861110&DB=EPODOC&CC=SE&NR=447389B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19861110&DB=EPODOC&CC=SE&NR=447389B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>4)E PALOSI</creatorcontrib><creatorcontrib>3)L BALASPIRI</creatorcontrib><creatorcontrib>2)T SZIRTES</creatorcontrib><creatorcontrib>5)L SPORNY</creatorcontrib><creatorcontrib>6)A SARKADI</creatorcontrib><creatorcontrib>1)L KISFALUDY</creatorcontrib><title>NYA TRIPEPTIDER, SOM INVERKAR PA DET CENTRALA NERVSYSTEMET</title><description>The invention relates to new peptide derivatives which act on the central nervous system and correspond to the general formula (I), X-Y-W-NH2 (I) wherein X is L-pyroglutamyl, D-pyroglutamyl, L-2-keto-imidazolidine-4-carbonyl, L-6-keto-pipecolyl, L-thiazolidine-4-carbonyl, L-prolyl or orotyl group, Y is L-leucyl, L-norvalyl or L-histidyl group, and W is L-prolyl, D-prolyl, L-thiazolidine-4-carbonyl, L-pipecolyl, L-homoprolyl, L-leucyl, L-isoleucyl, L-methionyl or D-pipecolyl group, or the W-NH2 group stands for pyrrolidyl or piperidyl group, with the proviso that if X is L-pyroglutamyl and Y is L-histidyl group, W is other than L-prolyl group, and pharmaceutically acceptable complexes thereof. These compounds are prepared by methods commonly applied in the peptide chemistry.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1986</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDyi3RUCAnyDHANCPF0cQ3SUQj291Xw9AtzDfJ2DFIIcFRwcQ1RcHb1Cwly9HFU8HMNCguODA5x9XUN4WFgTUvMKU7lhdLcDHJuriHOHrqpBfnxqcUFicmpeakl8cGuJibmxhaWTsYEFQAA1tAoEw</recordid><startdate>19861110</startdate><enddate>19861110</enddate><creator>4)E PALOSI</creator><creator>3)L BALASPIRI</creator><creator>2)T SZIRTES</creator><creator>5)L SPORNY</creator><creator>6)A SARKADI</creator><creator>1)L KISFALUDY</creator><scope>EVB</scope></search><sort><creationdate>19861110</creationdate><title>NYA TRIPEPTIDER, SOM INVERKAR PA DET CENTRALA NERVSYSTEMET</title><author>4)E PALOSI ; 3)L BALASPIRI ; 2)T SZIRTES ; 5)L SPORNY ; 6)A SARKADI ; 1)L KISFALUDY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SE447389B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>swe</language><creationdate>1986</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>4)E PALOSI</creatorcontrib><creatorcontrib>3)L BALASPIRI</creatorcontrib><creatorcontrib>2)T SZIRTES</creatorcontrib><creatorcontrib>5)L SPORNY</creatorcontrib><creatorcontrib>6)A SARKADI</creatorcontrib><creatorcontrib>1)L KISFALUDY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>4)E PALOSI</au><au>3)L BALASPIRI</au><au>2)T SZIRTES</au><au>5)L SPORNY</au><au>6)A SARKADI</au><au>1)L KISFALUDY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NYA TRIPEPTIDER, SOM INVERKAR PA DET CENTRALA NERVSYSTEMET</title><date>1986-11-10</date><risdate>1986</risdate><abstract>The invention relates to new peptide derivatives which act on the central nervous system and correspond to the general formula (I), X-Y-W-NH2 (I) wherein X is L-pyroglutamyl, D-pyroglutamyl, L-2-keto-imidazolidine-4-carbonyl, L-6-keto-pipecolyl, L-thiazolidine-4-carbonyl, L-prolyl or orotyl group, Y is L-leucyl, L-norvalyl or L-histidyl group, and W is L-prolyl, D-prolyl, L-thiazolidine-4-carbonyl, L-pipecolyl, L-homoprolyl, L-leucyl, L-isoleucyl, L-methionyl or D-pipecolyl group, or the W-NH2 group stands for pyrrolidyl or piperidyl group, with the proviso that if X is L-pyroglutamyl and Y is L-histidyl group, W is other than L-prolyl group, and pharmaceutically acceptable complexes thereof. These compounds are prepared by methods commonly applied in the peptide chemistry.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NYA TRIPEPTIDER, SOM INVERKAR PA DET CENTRALA NERVSYSTEMET |
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