SE369601
Compounds of formula (I) (where R is alkyl or aralkyl and X is halogen) and their salts. (I) are useful as coccidiostats for poultry and as intermediates for compounds displaying antibacterial activity (e.g. alkylation and hydrolysis give corresponding 1-alkyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-qu...
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| creator | FRANK J,HU MESZAROS Z,HU SZENTMIKLOSI P,HU KOERMOECZY G,HU CZASZAR J,HU |
| description | Compounds of formula (I) (where R is alkyl or aralkyl and X is halogen) and their salts. (I) are useful as coccidiostats for poultry and as intermediates for compounds displaying antibacterial activity (e.g. alkylation and hydrolysis give corresponding 1-alkyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-quinoline-3-carboxyl- ic acids). Usual dose is about 1 g/day. The pref. phosphorus oxyhalide is PCL3. The reaction with (II) is advantageously carried out in a solvent or in excess phosphorus oxyhalide pref. at the b.pt. of the medium. Catalysts (e.g. polyphosphoric acid) are advantageously used. (I) thus obtd. may be hydrolysed to the corresponding free acid, pref. with an alkali hydroxide in aqs. or alcoholic medium. |
| format | Patent |
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(I) are useful as coccidiostats for poultry and as intermediates for compounds displaying antibacterial activity (e.g. alkylation and hydrolysis give corresponding 1-alkyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-quinoline-3-carboxyl- ic acids). Usual dose is about 1 g/day. The pref. phosphorus oxyhalide is PCL3. The reaction with (II) is advantageously carried out in a solvent or in excess phosphorus oxyhalide pref. at the b.pt. of the medium. Catalysts (e.g. polyphosphoric acid) are advantageously used. (I) thus obtd. may be hydrolysed to the corresponding free acid, pref. with an alkali hydroxide in aqs. or alcoholic medium.</description><language>eng</language><subject>CHEMISTRY ; FODDER ; FOODS OR FOODSTUFFS ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; METALLURGY ; ORGANIC CHEMISTRY ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><creationdate>1974</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19740909&DB=EPODOC&CC=SE&NR=369601B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19740909&DB=EPODOC&CC=SE&NR=369601B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FRANK J,HU</creatorcontrib><creatorcontrib>MESZAROS Z,HU</creatorcontrib><creatorcontrib>SZENTMIKLOSI P,HU</creatorcontrib><creatorcontrib>KOERMOECZY G,HU</creatorcontrib><creatorcontrib>CZASZAR J,HU</creatorcontrib><title>SE369601</title><description>Compounds of formula (I) (where R is alkyl or aralkyl and X is halogen) and their salts. (I) are useful as coccidiostats for poultry and as intermediates for compounds displaying antibacterial activity (e.g. alkylation and hydrolysis give corresponding 1-alkyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-quinoline-3-carboxyl- ic acids). Usual dose is about 1 g/day. The pref. phosphorus oxyhalide is PCL3. The reaction with (II) is advantageously carried out in a solvent or in excess phosphorus oxyhalide pref. at the b.pt. of the medium. Catalysts (e.g. polyphosphoric acid) are advantageously used. (I) thus obtd. may be hydrolysed to the corresponding free acid, pref. with an alkali hydroxide in aqs. or alcoholic medium.</description><subject>CHEMISTRY</subject><subject>FODDER</subject><subject>FOODS OR FOODSTUFFS</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1974</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOAIdjU2szQzMORhYE1LzClO5YXS3Axybq4hzh66qQX58anFBYnJqXmpJfEw5U7GBBUAAGAYGZw</recordid><startdate>19740909</startdate><enddate>19740909</enddate><creator>FRANK J,HU</creator><creator>MESZAROS Z,HU</creator><creator>SZENTMIKLOSI P,HU</creator><creator>KOERMOECZY G,HU</creator><creator>CZASZAR J,HU</creator><scope>EVB</scope></search><sort><creationdate>19740909</creationdate><title>SE369601</title><author>FRANK J,HU ; MESZAROS Z,HU ; SZENTMIKLOSI P,HU ; KOERMOECZY G,HU ; CZASZAR J,HU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_SE369601B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1974</creationdate><topic>CHEMISTRY</topic><topic>FODDER</topic><topic>FOODS OR FOODSTUFFS</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><toplevel>online_resources</toplevel><creatorcontrib>FRANK J,HU</creatorcontrib><creatorcontrib>MESZAROS Z,HU</creatorcontrib><creatorcontrib>SZENTMIKLOSI P,HU</creatorcontrib><creatorcontrib>KOERMOECZY G,HU</creatorcontrib><creatorcontrib>CZASZAR J,HU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FRANK J,HU</au><au>MESZAROS Z,HU</au><au>SZENTMIKLOSI P,HU</au><au>KOERMOECZY G,HU</au><au>CZASZAR J,HU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SE369601</title><date>1974-09-09</date><risdate>1974</risdate><abstract>Compounds of formula (I) (where R is alkyl or aralkyl and X is halogen) and their salts. (I) are useful as coccidiostats for poultry and as intermediates for compounds displaying antibacterial activity (e.g. alkylation and hydrolysis give corresponding 1-alkyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-quinoline-3-carboxyl- ic acids). Usual dose is about 1 g/day. The pref. phosphorus oxyhalide is PCL3. The reaction with (II) is advantageously carried out in a solvent or in excess phosphorus oxyhalide pref. at the b.pt. of the medium. Catalysts (e.g. polyphosphoric acid) are advantageously used. (I) thus obtd. may be hydrolysed to the corresponding free acid, pref. with an alkali hydroxide in aqs. or alcoholic medium.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY FODDER FOODS OR FOODSTUFFS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES METALLURGY ORGANIC CHEMISTRY THEIR TREATMENT, NOT COVERED BY OTHER CLASSES |
| title | SE369601 |
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