METHOD OF SYNTHESIS OF HIGH-PURE BUSPYRONE AND ITS HYDROCHLORIDE

FIELD: organic chemistry. SUBSTANCE: product: 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl] -butyl] -8-aza-spiro- [4.5]decane-7,9-dione (buspyrone) of the formula (I)and its hydrochlorides exhibiting high purity degree. Method of synthesis involves the catalytic hydrogenization of 8-[4-[4-pyrimidine-2-...

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Hauptverfasser:	D'ULA SIMICH, TIBOR METSEI, MARGIT KSORDO, GABOR BLASHKO, EVA FURDIGA, ZHUDIT SEGO, KLARA REJTER, LASLO KONCH, KALMAN NAD, D'ONDI VERECHKI, ZOLTAN BUDAI, ATTILA MANDI, IMRE KLEBOVICH, ILONA STRUKHAR
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR RELEVANT APPARATUS TRANSPORTING
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