THIENOPYRROL DERIVATIVES FOR APPLICATION FOR TARGETING PROTEINS, COMPOSITIONS WITH SAID DERIVATIVES, METHODS AND APPLICATIONS
FIELD: chemistry.SUBSTANCE: invention relates to compounds modulating protein function for the purpose of restoring protein homeostasis, including the activity of cytokines, CK1α, GSPT1, aiolos and/or ikaros, as well as intercellular adhesion. Proposed in the present invention are methods for modula...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | TORRES, Eduardo FUNG, Lea CHAN, Kajl V. KH SALLIVAN, Robert MERKURIO, Frenk ERDMAN, Pol E |
| description | FIELD: chemistry.SUBSTANCE: invention relates to compounds modulating protein function for the purpose of restoring protein homeostasis, including the activity of cytokines, CK1α, GSPT1, aiolos and/or ikaros, as well as intercellular adhesion. Proposed in the present invention are methods for modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Proposed are compositions, including those in combination with other cytokines and inflammation mediators.EFFECT: ensured modulation of protein-mediated diseases.39 cl, 11 dwg, 8 tbl, 65 ex
Изобретение относится к соединениям, модулирующим функцию белков с целью восстановления гомеостаза белков, включая активность цитокинов, CK1α, GSPT1, aiolos и/или ikaros, а также межклеточную адгезию. В настоящем изобретении предложены способы модулирования заболеваний, опосредованных белками, таких как опосредованные цитокинами заболевания, расстройства, состояния или ответы. Предложены композиции, в том числе в комбинации с другими цитокинами и медиаторами воспаления. 2 н. и 37 з.п. ф-лы, 11 ил., 8 табл., 65 пр. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2771166C2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2771166C2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2771166C23</originalsourceid><addsrcrecordid>eNqNjL0KwjAURrs4iPoO9wHq0ArtHJK0udDmhuTa4lSKxEm0UFff3R8cOjp9nI_DWSdPNqgtuZP31IDSHjvB2OkAFXkQzjUo3wfZL7PwtWa0NThPrNGGFCS1jgJ-nAA9soEgUC1TKbSaDakAwqplM2yT1WW8znH3200ClWZp9nG6D3GexnO8xcfgj3lZZllRyPzwh_IC16E78g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>THIENOPYRROL DERIVATIVES FOR APPLICATION FOR TARGETING PROTEINS, COMPOSITIONS WITH SAID DERIVATIVES, METHODS AND APPLICATIONS</title><source>esp@cenet</source><creator>TORRES, Eduardo ; FUNG, Lea ; CHAN, Kajl V. KH ; SALLIVAN, Robert ; MERKURIO, Frenk ; ERDMAN, Pol E</creator><creatorcontrib>TORRES, Eduardo ; FUNG, Lea ; CHAN, Kajl V. KH ; SALLIVAN, Robert ; MERKURIO, Frenk ; ERDMAN, Pol E</creatorcontrib><description>FIELD: chemistry.SUBSTANCE: invention relates to compounds modulating protein function for the purpose of restoring protein homeostasis, including the activity of cytokines, CK1α, GSPT1, aiolos and/or ikaros, as well as intercellular adhesion. Proposed in the present invention are methods for modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Proposed are compositions, including those in combination with other cytokines and inflammation mediators.EFFECT: ensured modulation of protein-mediated diseases.39 cl, 11 dwg, 8 tbl, 65 ex
Изобретение относится к соединениям, модулирующим функцию белков с целью восстановления гомеостаза белков, включая активность цитокинов, CK1α, GSPT1, aiolos и/или ikaros, а также межклеточную адгезию. В настоящем изобретении предложены способы модулирования заболеваний, опосредованных белками, таких как опосредованные цитокинами заболевания, расстройства, состояния или ответы. Предложены композиции, в том числе в комбинации с другими цитокинами и медиаторами воспаления. 2 н. и 37 з.п. ф-лы, 11 ил., 8 табл., 65 пр.</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220427&DB=EPODOC&CC=RU&NR=2771166C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220427&DB=EPODOC&CC=RU&NR=2771166C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TORRES, Eduardo</creatorcontrib><creatorcontrib>FUNG, Lea</creatorcontrib><creatorcontrib>CHAN, Kajl V. KH</creatorcontrib><creatorcontrib>SALLIVAN, Robert</creatorcontrib><creatorcontrib>MERKURIO, Frenk</creatorcontrib><creatorcontrib>ERDMAN, Pol E</creatorcontrib><title>THIENOPYRROL DERIVATIVES FOR APPLICATION FOR TARGETING PROTEINS, COMPOSITIONS WITH SAID DERIVATIVES, METHODS AND APPLICATIONS</title><description>FIELD: chemistry.SUBSTANCE: invention relates to compounds modulating protein function for the purpose of restoring protein homeostasis, including the activity of cytokines, CK1α, GSPT1, aiolos and/or ikaros, as well as intercellular adhesion. Proposed in the present invention are methods for modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Proposed are compositions, including those in combination with other cytokines and inflammation mediators.EFFECT: ensured modulation of protein-mediated diseases.39 cl, 11 dwg, 8 tbl, 65 ex
Изобретение относится к соединениям, модулирующим функцию белков с целью восстановления гомеостаза белков, включая активность цитокинов, CK1α, GSPT1, aiolos и/или ikaros, а также межклеточную адгезию. В настоящем изобретении предложены способы модулирования заболеваний, опосредованных белками, таких как опосредованные цитокинами заболевания, расстройства, состояния или ответы. Предложены композиции, в том числе в комбинации с другими цитокинами и медиаторами воспаления. 2 н. и 37 з.п. ф-лы, 11 ил., 8 табл., 65 пр.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL0KwjAURrs4iPoO9wHq0ArtHJK0udDmhuTa4lSKxEm0UFff3R8cOjp9nI_DWSdPNqgtuZP31IDSHjvB2OkAFXkQzjUo3wfZL7PwtWa0NThPrNGGFCS1jgJ-nAA9soEgUC1TKbSaDakAwqplM2yT1WW8znH3200ClWZp9nG6D3GexnO8xcfgj3lZZllRyPzwh_IC16E78g</recordid><startdate>20220427</startdate><enddate>20220427</enddate><creator>TORRES, Eduardo</creator><creator>FUNG, Lea</creator><creator>CHAN, Kajl V. KH</creator><creator>SALLIVAN, Robert</creator><creator>MERKURIO, Frenk</creator><creator>ERDMAN, Pol E</creator><scope>EVB</scope></search><sort><creationdate>20220427</creationdate><title>THIENOPYRROL DERIVATIVES FOR APPLICATION FOR TARGETING PROTEINS, COMPOSITIONS WITH SAID DERIVATIVES, METHODS AND APPLICATIONS</title><author>TORRES, Eduardo ; FUNG, Lea ; CHAN, Kajl V. KH ; SALLIVAN, Robert ; MERKURIO, Frenk ; ERDMAN, Pol E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2771166C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TORRES, Eduardo</creatorcontrib><creatorcontrib>FUNG, Lea</creatorcontrib><creatorcontrib>CHAN, Kajl V. KH</creatorcontrib><creatorcontrib>SALLIVAN, Robert</creatorcontrib><creatorcontrib>MERKURIO, Frenk</creatorcontrib><creatorcontrib>ERDMAN, Pol E</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TORRES, Eduardo</au><au>FUNG, Lea</au><au>CHAN, Kajl V. KH</au><au>SALLIVAN, Robert</au><au>MERKURIO, Frenk</au><au>ERDMAN, Pol E</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THIENOPYRROL DERIVATIVES FOR APPLICATION FOR TARGETING PROTEINS, COMPOSITIONS WITH SAID DERIVATIVES, METHODS AND APPLICATIONS</title><date>2022-04-27</date><risdate>2022</risdate><abstract>FIELD: chemistry.SUBSTANCE: invention relates to compounds modulating protein function for the purpose of restoring protein homeostasis, including the activity of cytokines, CK1α, GSPT1, aiolos and/or ikaros, as well as intercellular adhesion. Proposed in the present invention are methods for modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Proposed are compositions, including those in combination with other cytokines and inflammation mediators.EFFECT: ensured modulation of protein-mediated diseases.39 cl, 11 dwg, 8 tbl, 65 ex
Изобретение относится к соединениям, модулирующим функцию белков с целью восстановления гомеостаза белков, включая активность цитокинов, CK1α, GSPT1, aiolos и/или ikaros, а также межклеточную адгезию. В настоящем изобретении предложены способы модулирования заболеваний, опосредованных белками, таких как опосредованные цитокинами заболевания, расстройства, состояния или ответы. Предложены композиции, в том числе в комбинации с другими цитокинами и медиаторами воспаления. 2 н. и 37 з.п. ф-лы, 11 ил., 8 табл., 65 пр.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2771166C2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIENOPYRROL DERIVATIVES FOR APPLICATION FOR TARGETING PROTEINS, COMPOSITIONS WITH SAID DERIVATIVES, METHODS AND APPLICATIONS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T14%3A26%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TORRES,%20Eduardo&rft.date=2022-04-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2771166C2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |