ARTIFICIAL GENE N1NEW, ENCODING NUCLEOCAPSID PROTEIN OF CORONAVIRUS SARS-CoV-2, AND RECOMBINANT PLASMID PET-28A-N1NEW, PROVIDING EXPRESSION OF THE ARTIFICIAL GENE

FIELD: biotechnology and immunology.SUBSTANCE: invention relates to biotechnology and immunology. A gene is proposed that allows the production of an artificial protein with immunogenic properties against SARS-CoV-2, a plasmid containing it, as well as the artificial protein itself, obtained using a...

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Hauptverfasser: Pletyukhina Yuliya Vladimirovna, Skvortsova Veronika Igorevna, Musa Rakhimovich Khaitov, Evtushenko Anatolij Eduardovich, Belozerova Natalya Sergeevna, Savelev Nikita Sergeevich, Fakhretdinova Liliya Niyazovna, Trukhin Viktor Pavlovich, Rabdano Sevastyan Olegovich
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creator Pletyukhina Yuliya Vladimirovna
Skvortsova Veronika Igorevna
Musa Rakhimovich Khaitov
Evtushenko Anatolij Eduardovich
Belozerova Natalya Sergeevna
Savelev Nikita Sergeevich
Fakhretdinova Liliya Niyazovna
Trukhin Viktor Pavlovich
Rabdano Sevastyan Olegovich
description FIELD: biotechnology and immunology.SUBSTANCE: invention relates to biotechnology and immunology. A gene is proposed that allows the production of an artificial protein with immunogenic properties against SARS-CoV-2, a plasmid containing it, as well as the artificial protein itself, obtained using an E. coli cell line modified by the described plasmid.EFFECT: resulting recombinant protein has immunogenic properties against SARS-CoV-2 and can be used as an active substance for obtaining a vaccine against SARS-CoV-2.5 cl, 3 dwg, 4 tbl, 6 ex Изобретение относится к биотехнологии и иммунологии. Предложены ген, позволяющий продуцировать искусственный белок, обладающий иммуногенными свойствами в отношении SARS-CoV-2, плазмида, его содержащая, а также сам искусственный белок, полученный с помощью клеточной линии E. coli, модифицированной описанной плазмидой. Полученный рекомбинантный белок обладает иммуногенными свойствами в отношении SARS-CoV-2 и может быть использован в качестве активной субстанции для получения вакцины против SARS-CoV-2. 4 н. и 1 з.п. ф-лы, 3 ил., 4 табл., 6 пр.
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A gene is proposed that allows the production of an artificial protein with immunogenic properties against SARS-CoV-2, a plasmid containing it, as well as the artificial protein itself, obtained using an E. coli cell line modified by the described plasmid.EFFECT: resulting recombinant protein has immunogenic properties against SARS-CoV-2 and can be used as an active substance for obtaining a vaccine against SARS-CoV-2.5 cl, 3 dwg, 4 tbl, 6 ex Изобретение относится к биотехнологии и иммунологии. Предложены ген, позволяющий продуцировать искусственный белок, обладающий иммуногенными свойствами в отношении SARS-CoV-2, плазмида, его содержащая, а также сам искусственный белок, полученный с помощью клеточной линии E. coli, модифицированной описанной плазмидой. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title ARTIFICIAL GENE N1NEW, ENCODING NUCLEOCAPSID PROTEIN OF CORONAVIRUS SARS-CoV-2, AND RECOMBINANT PLASMID PET-28A-N1NEW, PROVIDING EXPRESSION OF THE ARTIFICIAL GENE
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