METHOD FOR DIAGNOSING HEPATOCELLULAR CARCINOMA BY DETERMINING COEFFICIENT OF DEVELOPMENT OF HEPATOCELLULAR CARCINOMA BASED ON CHANGES IN T LEVELS OF MICRORNA EXPRESSION IN HUMAN BLOOD PLASMA AND SALIVA
FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, namely, to diagnostic methods providing a possibility of diagnosing the development of a malignant tumour. The method consists in determining the coefficient diagnosing the development of hepatocellular carcinoma, calcu...
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| creator | Petkevich Alisa Antonovna Malinina Natalya Anatolevna Abramov Aleksandr Andreevich |
| description | FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, namely, to diagnostic methods providing a possibility of diagnosing the development of a malignant tumour. The method consists in determining the coefficient diagnosing the development of hepatocellular carcinoma, calculated based on the changes in the expression profile of the following microRNAs in the blood plasma or saliva: microRNA-let-7a, microRNA-18, microRNA-21, microRNA-22, microRNA-26a, microRNA-34a, microRNA-101, microRNA-103, microRNA-106b, microRNA-122, microRNA-221, microRNA-145, microRNA-222, microRNA-223, microRNA-224, microRNA-1246.EFFECT: method allows for diagnostics of hepatocellular carcinoma in patients with hepatic cirrhosis due to hepatitis C.2 cl, 6 tbl, 2 ex
Изобретение относится к области биотехнологии, а именно к диагностическим методам, позволяющим диагностировать развитие злокачественной опухоли. Способ заключается в определении коэффициента, диагностирующего развитие гепатоцеллюлярной карциномы, рассчитываемого на основании изменений профиля уровней экспрессии следующих микроРНК в плазме крови или слюне: микроPHK-let-7a, микроРНК-18, микроРНК-21, микроРНК-22, микроРНК-26а, микроРНК-34а, микроРНК-101, микроРНК-103, микроРНК-106b, микроРНК-122, микроРНК-221, микроРНК-145, микроРНК-222, микроРНК-223, микроРНК-224, микроРНК-1246. Способ позволяет диагностировать гепатоцеллюлярную карциному среди пациентов с циррозом печени вследствие перенесенного гепатита С. 2 н.п. ф-лы, 6 табл., 2 пр. |
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Изобретение относится к области биотехнологии, а именно к диагностическим методам, позволяющим диагностировать развитие злокачественной опухоли. Способ заключается в определении коэффициента, диагностирующего развитие гепатоцеллюлярной карциномы, рассчитываемого на основании изменений профиля уровней экспрессии следующих микроРНК в плазме крови или слюне: микроPHK-let-7a, микроРНК-18, микроРНК-21, микроРНК-22, микроРНК-26а, микроРНК-34а, микроРНК-101, микроРНК-103, микроРНК-106b, микроРНК-122, микроРНК-221, микроРНК-145, микроРНК-222, микроРНК-223, микроРНК-224, микроРНК-1246. Способ позволяет диагностировать гепатоцеллюлярную карциному среди пациентов с циррозом печени вследствие перенесенного гепатита С. 2 н.п. ф-лы, 6 табл., 2 пр.</description><language>eng ; rus</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211201&DB=EPODOC&CC=RU&NR=2760937C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211201&DB=EPODOC&CC=RU&NR=2760937C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Petkevich Alisa Antonovna</creatorcontrib><creatorcontrib>Malinina Natalya Anatolevna</creatorcontrib><creatorcontrib>Abramov Aleksandr Andreevich</creatorcontrib><title>METHOD FOR DIAGNOSING HEPATOCELLULAR CARCINOMA BY DETERMINING COEFFICIENT OF DEVELOPMENT OF HEPATOCELLULAR CARCINOMA BASED ON CHANGES IN T LEVELS OF MICRORNA EXPRESSION IN HUMAN BLOOD PLASMA AND SALIVA</title><description>FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, namely, to diagnostic methods providing a possibility of diagnosing the development of a malignant tumour. The method consists in determining the coefficient diagnosing the development of hepatocellular carcinoma, calculated based on the changes in the expression profile of the following microRNAs in the blood plasma or saliva: microRNA-let-7a, microRNA-18, microRNA-21, microRNA-22, microRNA-26a, microRNA-34a, microRNA-101, microRNA-103, microRNA-106b, microRNA-122, microRNA-221, microRNA-145, microRNA-222, microRNA-223, microRNA-224, microRNA-1246.EFFECT: method allows for diagnostics of hepatocellular carcinoma in patients with hepatic cirrhosis due to hepatitis C.2 cl, 6 tbl, 2 ex
Изобретение относится к области биотехнологии, а именно к диагностическим методам, позволяющим диагностировать развитие злокачественной опухоли. Способ заключается в определении коэффициента, диагностирующего развитие гепатоцеллюлярной карциномы, рассчитываемого на основании изменений профиля уровней экспрессии следующих микроРНК в плазме крови или слюне: микроPHK-let-7a, микроРНК-18, микроРНК-21, микроРНК-22, микроРНК-26а, микроРНК-34а, микроРНК-101, микроРНК-103, микроРНК-106b, микроРНК-122, микроРНК-221, микроРНК-145, микроРНК-222, микроРНК-223, микроРНК-224, микроРНК-1246. Способ позволяет диагностировать гепатоцеллюлярную карциному среди пациентов с циррозом печени вследствие перенесенного гепатита С. 2 н.п. ф-лы, 6 табл., 2 пр.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjsFKA0EQRPfiQdR_6B8QogGDx05Pz07DTPcyMxviKYQwnkQD8Sf9K2chV8FTUdSrom6Hn8Q1mANvGZzgqFZERwg8YTXiGOeIGQgziVpC2L6B48o5iS4cGXsvJKwVzPdox9GmdLV_r2BhB6ZAAXXkAqJQIS7tshSTULasCLyfMpciHe1ImBMqbKP1w1PE0pdQHRSMssP74eb9-HFpD1e9G8BzpfDYzl-HdjkfT-2zfR_y_Lx5Wb2uN_S0_gfyC6QVT4w</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Petkevich Alisa Antonovna</creator><creator>Malinina Natalya Anatolevna</creator><creator>Abramov Aleksandr Andreevich</creator><scope>EVB</scope></search><sort><creationdate>20211201</creationdate><title>METHOD FOR DIAGNOSING HEPATOCELLULAR CARCINOMA BY DETERMINING COEFFICIENT OF DEVELOPMENT OF HEPATOCELLULAR CARCINOMA BASED ON CHANGES IN T LEVELS OF MICRORNA EXPRESSION IN HUMAN BLOOD PLASMA AND SALIVA</title><author>Petkevich Alisa Antonovna ; Malinina Natalya Anatolevna ; Abramov Aleksandr Andreevich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2760937C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2021</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Petkevich Alisa Antonovna</creatorcontrib><creatorcontrib>Malinina Natalya Anatolevna</creatorcontrib><creatorcontrib>Abramov Aleksandr Andreevich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Petkevich Alisa Antonovna</au><au>Malinina Natalya Anatolevna</au><au>Abramov Aleksandr Andreevich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR DIAGNOSING HEPATOCELLULAR CARCINOMA BY DETERMINING COEFFICIENT OF DEVELOPMENT OF HEPATOCELLULAR CARCINOMA BASED ON CHANGES IN T LEVELS OF MICRORNA EXPRESSION IN HUMAN BLOOD PLASMA AND SALIVA</title><date>2021-12-01</date><risdate>2021</risdate><abstract>FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, namely, to diagnostic methods providing a possibility of diagnosing the development of a malignant tumour. The method consists in determining the coefficient diagnosing the development of hepatocellular carcinoma, calculated based on the changes in the expression profile of the following microRNAs in the blood plasma or saliva: microRNA-let-7a, microRNA-18, microRNA-21, microRNA-22, microRNA-26a, microRNA-34a, microRNA-101, microRNA-103, microRNA-106b, microRNA-122, microRNA-221, microRNA-145, microRNA-222, microRNA-223, microRNA-224, microRNA-1246.EFFECT: method allows for diagnostics of hepatocellular carcinoma in patients with hepatic cirrhosis due to hepatitis C.2 cl, 6 tbl, 2 ex
Изобретение относится к области биотехнологии, а именно к диагностическим методам, позволяющим диагностировать развитие злокачественной опухоли. Способ заключается в определении коэффициента, диагностирующего развитие гепатоцеллюлярной карциномы, рассчитываемого на основании изменений профиля уровней экспрессии следующих микроРНК в плазме крови или слюне: микроPHK-let-7a, микроРНК-18, микроРНК-21, микроРНК-22, микроРНК-26а, микроРНК-34а, микроРНК-101, микроРНК-103, микроРНК-106b, микроРНК-122, микроРНК-221, микроРНК-145, микроРНК-222, микроРНК-223, микроРНК-224, микроРНК-1246. Способ позволяет диагностировать гепатоцеллюлярную карциному среди пациентов с циррозом печени вследствие перенесенного гепатита С. 2 н.п. ф-лы, 6 табл., 2 пр.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | METHOD FOR DIAGNOSING HEPATOCELLULAR CARCINOMA BY DETERMINING COEFFICIENT OF DEVELOPMENT OF HEPATOCELLULAR CARCINOMA BASED ON CHANGES IN T LEVELS OF MICRORNA EXPRESSION IN HUMAN BLOOD PLASMA AND SALIVA |
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