MULTIVALENT AND MULTISPECIFIC HYBRID PROTEINS THAT BIND TO DR5
FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, specifically to the preparation of a polypeptide binding to death receptor 5 (DR5), and can be used in medicine.EFFECT: resulting polypeptide contains many DR5-binding domains (DR5BD) representing VHH and can be used in...
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| creator | KHUSSEJN Abrakhim VILLIS Ketlin M RAZAI Amir S DZHONS Kajl S DEVERO Kuinn TIMMER Dzhon K EKELMAN Brendan P |
| description | FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, specifically to the preparation of a polypeptide binding to death receptor 5 (DR5), and can be used in medicine.EFFECT: resulting polypeptide contains many DR5-binding domains (DR5BD) representing VHH and can be used in effective cancer therapy or to reduce the number of regulatory T cells.41 cl, 9 dwg, 4 ex
Изобретение относится к области биотехнологии, конкретно к получению полипептида, связывающемуся с рецептором смерти 5 (DR5), и может быть использовано в медицине. Полученный полипептид содержит множество DR5-связывающих доменов (DR5BD) представляющих собой VHH и может быть использован в эффективной терапии рака или для уменьшения числа регуляторных Т-клеток. 12 н. и 29 з.п. ф-лы, 4 пр., 9 ил. |
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Изобретение относится к области биотехнологии, конкретно к получению полипептида, связывающемуся с рецептором смерти 5 (DR5), и может быть использовано в медицине. Полученный полипептид содержит множество DR5-связывающих доменов (DR5BD) представляющих собой VHH и может быть использован в эффективной терапии рака или для уменьшения числа регуляторных Т-клеток. 12 н. и 29 з.п. ф-лы, 4 пр., 9 ил.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | MULTIVALENT AND MULTISPECIFIC HYBRID PROTEINS THAT BIND TO DR5 |
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