STRAIN STREPTOMYCES TENDAE - PRODUCER OF ANTIBACTERIAL ANTIBIOTIC INA 5812
FIELD: biotechnology.SUBSTANCE: invention can be used in biotechnology for production of antibacterial agent INA 5812. Antibiotic INA 5812 according to the chemical structure is an original linear-cyclic glycopeptide compound which is active against gram-positive pathogens in vitro and highly effect...
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creator | Pogozheva Valeriya Vladimirovna Kulyaeva Valeriya Viktorovna Korshun Vladimir Arkadevich Yakovenko Alla Nikolaevna Kharitonova Lidiya Aleksandrovna Tyurin Anton Pavlovich Katrukha Genrikh Stepanovich Filicheva Valentina Andreevna Lapchinskaya Olda Anastasevna Lapchinskaya Mariya Yulevna Ponomarenko Valerij Ivanovich Orlova Galina Ivanovna |
description | FIELD: biotechnology.SUBSTANCE: invention can be used in biotechnology for production of antibacterial agent INA 5812. Antibiotic INA 5812 according to the chemical structure is an original linear-cyclic glycopeptide compound which is active against gram-positive pathogens in vitro and highly effective in experiments in vivo in the experimental treatment of staphylococcal sepsis in white mice. Disclosed is a new strain - producer of antibiotic INA 55812 by selective transformation of properties of soil culture Streptomyces tendae. Strain is deposited in the collection of cultures of BRC VKPM SRC "Kurchatov Institute"-Genetika number VKPM Ac-1980.EFFECT: strain Streptomyces tendae VKPM Ac-1980 has high antibiotic activity and accumulates 2,500 microgram/ml of antibacterial INA 5812 in deep cultivation.1 cl, 2 tbl, 1 ex
Изобретение может быть использовано в биотехнологии для производства противобактериального антибиотика ИНА 5812. Антибиотик ИНА 5812 по химическому строению является оригинальным линейно-циклическим гликопептидным соединением, активным в отношении грамположительных патогенов in vitro и высокоэффективным в опытах in vivo при экспериментальном лечении стафилококкового сепсиса у белых мышей. Предлагается новый штамм - продуцент антибиотика ИНА 55812 путем селекционного преобразования свойств почвенной культуры Streptomyces tendae. Штамм депонирован в коллекции культур БРЦ ВКПМ НИЦ «Курчатовский институт»-ГосНИИгенетика под номером ВКПМ Ас-1980. Штамм Streptomyces tendae ВКПМ Ас-1980 обладает повышенной антибиотической активностью и при глубинном культивировании накапливает 2500 мкг/мл противобактериального антибиотика ИНА 5812. 2 табл., 1 пр. |
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Изобретение может быть использовано в биотехнологии для производства противобактериального антибиотика ИНА 5812. Антибиотик ИНА 5812 по химическому строению является оригинальным линейно-циклическим гликопептидным соединением, активным в отношении грамположительных патогенов in vitro и высокоэффективным в опытах in vivo при экспериментальном лечении стафилококкового сепсиса у белых мышей. Предлагается новый штамм - продуцент антибиотика ИНА 55812 путем селекционного преобразования свойств почвенной культуры Streptomyces tendae. Штамм депонирован в коллекции культур БРЦ ВКПМ НИЦ «Курчатовский институт»-ГосНИИгенетика под номером ВКПМ Ас-1980. Штамм Streptomyces tendae ВКПМ Ас-1980 обладает повышенной антибиотической активностью и при глубинном культивировании накапливает 2500 мкг/мл противобактериального антибиотика ИНА 5812. 2 табл., 1 пр.</description><language>eng ; rus</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200110&DB=EPODOC&CC=RU&NR=2710733C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200110&DB=EPODOC&CC=RU&NR=2710733C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Pogozheva Valeriya Vladimirovna</creatorcontrib><creatorcontrib>Kulyaeva Valeriya Viktorovna</creatorcontrib><creatorcontrib>Korshun Vladimir Arkadevich</creatorcontrib><creatorcontrib>Yakovenko Alla Nikolaevna</creatorcontrib><creatorcontrib>Kharitonova Lidiya Aleksandrovna</creatorcontrib><creatorcontrib>Tyurin Anton Pavlovich</creatorcontrib><creatorcontrib>Katrukha Genrikh Stepanovich</creatorcontrib><creatorcontrib>Filicheva Valentina Andreevna</creatorcontrib><creatorcontrib>Lapchinskaya Olda Anastasevna</creatorcontrib><creatorcontrib>Lapchinskaya Mariya Yulevna</creatorcontrib><creatorcontrib>Ponomarenko Valerij Ivanovich</creatorcontrib><creatorcontrib>Orlova Galina Ivanovna</creatorcontrib><title>STRAIN STREPTOMYCES TENDAE - PRODUCER OF ANTIBACTERIAL ANTIBIOTIC INA 5812</title><description>FIELD: biotechnology.SUBSTANCE: invention can be used in biotechnology for production of antibacterial agent INA 5812. Antibiotic INA 5812 according to the chemical structure is an original linear-cyclic glycopeptide compound which is active against gram-positive pathogens in vitro and highly effective in experiments in vivo in the experimental treatment of staphylococcal sepsis in white mice. Disclosed is a new strain - producer of antibiotic INA 55812 by selective transformation of properties of soil culture Streptomyces tendae. Strain is deposited in the collection of cultures of BRC VKPM SRC "Kurchatov Institute"-Genetika number VKPM Ac-1980.EFFECT: strain Streptomyces tendae VKPM Ac-1980 has high antibiotic activity and accumulates 2,500 microgram/ml of antibacterial INA 5812 in deep cultivation.1 cl, 2 tbl, 1 ex
Изобретение может быть использовано в биотехнологии для производства противобактериального антибиотика ИНА 5812. Антибиотик ИНА 5812 по химическому строению является оригинальным линейно-циклическим гликопептидным соединением, активным в отношении грамположительных патогенов in vitro и высокоэффективным в опытах in vivo при экспериментальном лечении стафилококкового сепсиса у белых мышей. Предлагается новый штамм - продуцент антибиотика ИНА 55812 путем селекционного преобразования свойств почвенной культуры Streptomyces tendae. Штамм депонирован в коллекции культур БРЦ ВКПМ НИЦ «Курчатовский институт»-ГосНИИгенетика под номером ВКПМ Ас-1980. Штамм Streptomyces tendae ВКПМ Ас-1980 обладает повышенной антибиотической активностью и при глубинном культивировании накапливает 2500 мкг/мл противобактериального антибиотика ИНА 5812. 2 табл., 1 пр.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAKDgly9PRTAFKuASH-vpHOrsEKIa5-Lo6uCroKAUH-LqHOrkEK_m4Kjn4hnk6OziGuQZ6OPhCep3-Ip7OCp5-jgqmFoREPA2taYk5xKi-U5mZQcHMNcfbQTS3Ij08tLkhMTs1LLYkPCjUyNzQwNzZ2NjQmQgkA6qgsqg</recordid><startdate>20200110</startdate><enddate>20200110</enddate><creator>Pogozheva Valeriya Vladimirovna</creator><creator>Kulyaeva Valeriya Viktorovna</creator><creator>Korshun Vladimir Arkadevich</creator><creator>Yakovenko Alla Nikolaevna</creator><creator>Kharitonova Lidiya Aleksandrovna</creator><creator>Tyurin Anton Pavlovich</creator><creator>Katrukha Genrikh Stepanovich</creator><creator>Filicheva Valentina Andreevna</creator><creator>Lapchinskaya Olda Anastasevna</creator><creator>Lapchinskaya Mariya Yulevna</creator><creator>Ponomarenko Valerij Ivanovich</creator><creator>Orlova Galina Ivanovna</creator><scope>EVB</scope></search><sort><creationdate>20200110</creationdate><title>STRAIN STREPTOMYCES TENDAE - PRODUCER OF ANTIBACTERIAL ANTIBIOTIC INA 5812</title><author>Pogozheva Valeriya Vladimirovna ; Kulyaeva Valeriya Viktorovna ; Korshun Vladimir Arkadevich ; Yakovenko Alla Nikolaevna ; Kharitonova Lidiya Aleksandrovna ; Tyurin Anton Pavlovich ; Katrukha Genrikh Stepanovich ; Filicheva Valentina Andreevna ; Lapchinskaya Olda Anastasevna ; Lapchinskaya Mariya Yulevna ; Ponomarenko Valerij Ivanovich ; Orlova Galina Ivanovna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2710733C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2020</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Pogozheva Valeriya Vladimirovna</creatorcontrib><creatorcontrib>Kulyaeva Valeriya Viktorovna</creatorcontrib><creatorcontrib>Korshun Vladimir Arkadevich</creatorcontrib><creatorcontrib>Yakovenko Alla Nikolaevna</creatorcontrib><creatorcontrib>Kharitonova Lidiya Aleksandrovna</creatorcontrib><creatorcontrib>Tyurin Anton Pavlovich</creatorcontrib><creatorcontrib>Katrukha Genrikh Stepanovich</creatorcontrib><creatorcontrib>Filicheva Valentina Andreevna</creatorcontrib><creatorcontrib>Lapchinskaya Olda Anastasevna</creatorcontrib><creatorcontrib>Lapchinskaya Mariya Yulevna</creatorcontrib><creatorcontrib>Ponomarenko Valerij Ivanovich</creatorcontrib><creatorcontrib>Orlova Galina Ivanovna</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Pogozheva Valeriya Vladimirovna</au><au>Kulyaeva Valeriya Viktorovna</au><au>Korshun Vladimir Arkadevich</au><au>Yakovenko Alla Nikolaevna</au><au>Kharitonova Lidiya Aleksandrovna</au><au>Tyurin Anton Pavlovich</au><au>Katrukha Genrikh Stepanovich</au><au>Filicheva Valentina Andreevna</au><au>Lapchinskaya Olda Anastasevna</au><au>Lapchinskaya Mariya Yulevna</au><au>Ponomarenko Valerij Ivanovich</au><au>Orlova Galina Ivanovna</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>STRAIN STREPTOMYCES TENDAE - PRODUCER OF ANTIBACTERIAL ANTIBIOTIC INA 5812</title><date>2020-01-10</date><risdate>2020</risdate><abstract>FIELD: biotechnology.SUBSTANCE: invention can be used in biotechnology for production of antibacterial agent INA 5812. Antibiotic INA 5812 according to the chemical structure is an original linear-cyclic glycopeptide compound which is active against gram-positive pathogens in vitro and highly effective in experiments in vivo in the experimental treatment of staphylococcal sepsis in white mice. Disclosed is a new strain - producer of antibiotic INA 55812 by selective transformation of properties of soil culture Streptomyces tendae. Strain is deposited in the collection of cultures of BRC VKPM SRC "Kurchatov Institute"-Genetika number VKPM Ac-1980.EFFECT: strain Streptomyces tendae VKPM Ac-1980 has high antibiotic activity and accumulates 2,500 microgram/ml of antibacterial INA 5812 in deep cultivation.1 cl, 2 tbl, 1 ex
Изобретение может быть использовано в биотехнологии для производства противобактериального антибиотика ИНА 5812. Антибиотик ИНА 5812 по химическому строению является оригинальным линейно-циклическим гликопептидным соединением, активным в отношении грамположительных патогенов in vitro и высокоэффективным в опытах in vivo при экспериментальном лечении стафилококкового сепсиса у белых мышей. Предлагается новый штамм - продуцент антибиотика ИНА 55812 путем селекционного преобразования свойств почвенной культуры Streptomyces tendae. Штамм депонирован в коллекции культур БРЦ ВКПМ НИЦ «Курчатовский институт»-ГосНИИгенетика под номером ВКПМ Ас-1980. Штамм Streptomyces tendae ВКПМ Ас-1980 обладает повышенной антибиотической активностью и при глубинном культивировании накапливает 2500 мкг/мл противобактериального антибиотика ИНА 5812. 2 табл., 1 пр.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
title | STRAIN STREPTOMYCES TENDAE - PRODUCER OF ANTIBACTERIAL ANTIBIOTIC INA 5812 |
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