DERIVATIVES OF THIENO[2,3-C]PYRANS AS CFTR MODULATORS
FIELD: chemistry.SUBSTANCE: invention refers to compounds specified in: N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide and 2- (2-hydroxybenzamido)-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide.EFFECT: treating cystic fibrosi...
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| creator | DROPSIT-MONTOVER Sebasten Zhan-Zhak Sedrik KELGTERMANS Khans VAN DER PLAS Stiven Emiel ENDRYUS Martin Dzhejms Inglis MARTINA Sebasten Loran Ksave |
| description | FIELD: chemistry.SUBSTANCE: invention refers to compounds specified in: N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide and 2- (2-hydroxybenzamido)-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide.EFFECT: treating cystic fibrosis or chronic obstructive pulmonary disease (COPD).5 cl, 21 dwg
Изобретение относится к соединениям, выбранным из: N-(3-карбамоил-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-2-ил)-1H-пиразол-5-карбоксамида и 2-(2-гидроксибензамидо)-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-3-карбоксамида, предназначенных для лечения кистозного фиброза или хронического обструктивного заболевания легких (ХОЗЛ). 3 н. и 2 з.п. ф-лы, 21 табл. |
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Изобретение относится к соединениям, выбранным из: N-(3-карбамоил-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-2-ил)-1H-пиразол-5-карбоксамида и 2-(2-гидроксибензамидо)-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-3-карбоксамида, предназначенных для лечения кистозного фиброза или хронического обструктивного заболевания легких (ХОЗЛ). 3 н. и 2 з.п. ф-лы, 21 табл.</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191211&DB=EPODOC&CC=RU&NR=2708690C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191211&DB=EPODOC&CC=RU&NR=2708690C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DROPSIT-MONTOVER Sebasten Zhan-Zhak Sedrik</creatorcontrib><creatorcontrib>KELGTERMANS Khans</creatorcontrib><creatorcontrib>VAN DER PLAS Stiven Emiel</creatorcontrib><creatorcontrib>ENDRYUS Martin Dzhejms Inglis</creatorcontrib><creatorcontrib>MARTINA Sebasten Loran Ksave</creatorcontrib><title>DERIVATIVES OF THIENO[2,3-C]PYRANS AS CFTR MODULATORS</title><description>FIELD: chemistry.SUBSTANCE: invention refers to compounds specified in: N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide and 2- (2-hydroxybenzamido)-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide.EFFECT: treating cystic fibrosis or chronic obstructive pulmonary disease (COPD).5 cl, 21 dwg
Изобретение относится к соединениям, выбранным из: N-(3-карбамоил-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-2-ил)-1H-пиразол-5-карбоксамида и 2-(2-гидроксибензамидо)-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-3-карбоксамида, предназначенных для лечения кистозного фиброза или хронического обструктивного заболевания легких (ХОЗЛ). 3 н. и 2 з.п. ф-лы, 21 табл.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB1cQ3yDHMM8QxzDVbwd1MI8fB09fOPNtIx1nWODYgMcvQLVnAMVnB2CwlS8PV3CfVxDPEPCuZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfFBoUbmBhZmlgbORsZEKAEAsuQnkw</recordid><startdate>20191211</startdate><enddate>20191211</enddate><creator>DROPSIT-MONTOVER Sebasten Zhan-Zhak Sedrik</creator><creator>KELGTERMANS Khans</creator><creator>VAN DER PLAS Stiven Emiel</creator><creator>ENDRYUS Martin Dzhejms Inglis</creator><creator>MARTINA Sebasten Loran Ksave</creator><scope>EVB</scope></search><sort><creationdate>20191211</creationdate><title>DERIVATIVES OF THIENO[2,3-C]PYRANS AS CFTR MODULATORS</title><author>DROPSIT-MONTOVER Sebasten Zhan-Zhak Sedrik ; KELGTERMANS Khans ; VAN DER PLAS Stiven Emiel ; ENDRYUS Martin Dzhejms Inglis ; MARTINA Sebasten Loran Ksave</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2708690C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DROPSIT-MONTOVER Sebasten Zhan-Zhak Sedrik</creatorcontrib><creatorcontrib>KELGTERMANS Khans</creatorcontrib><creatorcontrib>VAN DER PLAS Stiven Emiel</creatorcontrib><creatorcontrib>ENDRYUS Martin Dzhejms Inglis</creatorcontrib><creatorcontrib>MARTINA Sebasten Loran Ksave</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DROPSIT-MONTOVER Sebasten Zhan-Zhak Sedrik</au><au>KELGTERMANS Khans</au><au>VAN DER PLAS Stiven Emiel</au><au>ENDRYUS Martin Dzhejms Inglis</au><au>MARTINA Sebasten Loran Ksave</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVATIVES OF THIENO[2,3-C]PYRANS AS CFTR MODULATORS</title><date>2019-12-11</date><risdate>2019</risdate><abstract>FIELD: chemistry.SUBSTANCE: invention refers to compounds specified in: N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide and 2- (2-hydroxybenzamido)-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide.EFFECT: treating cystic fibrosis or chronic obstructive pulmonary disease (COPD).5 cl, 21 dwg
Изобретение относится к соединениям, выбранным из: N-(3-карбамоил-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-2-ил)-1H-пиразол-5-карбоксамида и 2-(2-гидроксибензамидо)-5,5,7,7-тетраметил-5,7-дигидро-4H-тиено[2,3-c]пиран-3-карбоксамида, предназначенных для лечения кистозного фиброза или хронического обструктивного заболевания легких (ХОЗЛ). 3 н. и 2 з.п. ф-лы, 21 табл.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVATIVES OF THIENO[2,3-C]PYRANS AS CFTR MODULATORS |
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