MUS MUSCULUS HYBRID CULTIVATED ANIMAL CELLS STRAIN α - THE PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO THE CANCER-TESTICULAR ANTIGEN OF THE PERSON GAGE

FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, in particular to hybridoma technology, and is a strain of hybrid cells of mus musculus α - producer of monoclonal antibodies to the human cancer-testicular antigen GAGE. Strain is deposited in the All-Russian Collection...

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Hauptverfasser: Baryshnikova Mariya Anatolevna, Shprakh Zoya Sergeevna, Finashutina Yuliya Pavlovna, Golubtsova Natalya Valerevna, Misyurin Andrej Vitalevich
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creator Baryshnikova Mariya Anatolevna
Shprakh Zoya Sergeevna
Finashutina Yuliya Pavlovna
Golubtsova Natalya Valerevna
Misyurin Andrej Vitalevich
description FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, in particular to hybridoma technology, and is a strain of hybrid cells of mus musculus α - producer of monoclonal antibodies to the human cancer-testicular antigen GAGE. Strain is deposited in the All-Russian Collection of Industrial Microorganisms FSUE State Research Institute of Genetics of the Ministry of Education and Science of the Russian Federation (BRC VKPM) under the number N-174.EFFECT: invention makes it possible to obtain highly specific monoclonal antibodies that can be used in experimental oncology to study the structural and functional properties of GAGE family proteins in cell cultures and clinical samples.1 cl, 3 dwg, 2 tbl, 3 ex Изобретение относится к области биотехнологии, в частности к гибридомной технологии, и представляет собой штамм гибридных клеток mus musculus α - продуцент моноклональных антител к раково-тестикулярному антигену человека GAGE. Штамм депонирован во Всероссийской коллекции промышленных микроорганизмов ФГУП ГосНИИгенетика Минобрнауки России (БРЦ ВКПМ) под номером Н-174. Изобретение позволяет получить высокоспецифичные моноклональные антитела, которые могут использоваться в экспериментальной онкологии для изучения структурно-функциональных свойств белков семейства GAGE в культурах клеток и клинических образцах. 3 ил., 2 табл., 3 пр.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title MUS MUSCULUS HYBRID CULTIVATED ANIMAL CELLS STRAIN α - THE PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO THE CANCER-TESTICULAR ANTIGEN OF THE PERSON GAGE
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