METHOD OF MANAGEMENT OF PREGNANCY WITH INFECTIOUS PATHOLOGY OF UROGENITAL TRACT
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynecology, and may be used for management of pregnant women with an infectious pathology of the urogenital tract. To do this, the expression of the genes of the gamma gene of innate immunity - TLR, is examined. When e...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Egorova Ekaterina Aleksandrovna Bajrakova Aleksandra Lvovna Metelskaya Valeriya Alekseevna Afanasev Stanislav Stepanovich Pylev Andrej Lvovich Nesvizhskij Yurij Vladimirovich Karaulov Aleksandr Viktorovich Borisova Olga Yurevna Bochkareva Svetlana Sergeevna Chesheva Vera Vasilevna Savchenko Tatyana Nikolaevna Voropaeva Elena Aleksandrovna Aleshkin Vladimir Andrianovich Aleshkin Andrej Vladimirovich Grechishnikova Olga Gennadievna Agaeva Madina Ilyasovna Voropaev Aleksandr Dmitrievich Tolstova Ekaterina Sergeevna Afanasev Maksim Stanislavovich Urban Yuliya Nikolaevna Zatevalov Aleksandr Mikhajlovich |
| description | FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynecology, and may be used for management of pregnant women with an infectious pathology of the urogenital tract. To do this, the expression of the genes of the gamma gene of innate immunity - TLR, is examined. When establishing TLR-2 gene expression levels of 21.2 OE and above, TLR-4 23.0 OE and above, TLR-8 of 25.7 OE and above conduct emergency prophylaxis of abortion with prescription of vitamin therapy, antibiotic therapy, intravenous immunoglobulin and immunomodulator with antimicrobial activity. In this case, as an immunomodulator with antibacterial activity, kipferon can be used.EFFECT: method allows to achieve an adequate response to treatment by increasing the reliability of the prognosis of pregnancy during optimization of correction of management and treatment of pregnant women with an integrated assessment of the reactivity of the body and the course of pregnancy and prevention of complications of antibiotic therapy by clarifying the indications for its conduct by excluding it from a certain contingent of pregnant women.1 cl, 8 ex
Изобретение относится к медицине, а именно к акушерству и гинекологии, и может быть использовано для ведения беременных с инфекционной патологией урогенитального тракта. Для этого исследуют экспрессию генов рецепторов врожденного иммунитета - TLR. При установлении уровней экспрессии генов TLR-2 21,2 ОЕ и выше, TLR-4 23,0 ОЕ и выше, TLR-8 25,7 ОЕ и выше проводят экстренную профилактику прерывания беременности с назначением витаминотерапии, антибиотикотерапии, внутривенного иммуноглобулина и иммуномодулятора с антимикробной активностью. При этом в качестве иммуномодулятора с антибактериальной активностью может быть использован кипферон. Способ позволяет достичь адекватного ответа на лечение за счет повышения достоверности прогноза течения беременности при оптимизации коррекции ведения и лечения беременных с учетом интегральной оценки реактивности организма и течения беременности и профилактике осложнений антибактериальной терапии путем уточнения показаний к ее проведению за счет исключения ее проведения у определенного контингента беременных. 1 з.п. ф-лы, 8 пр. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2649127C1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2649127C1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2649127C13</originalsourceid><addsrcrecordid>eNrjZPD3dQ3x8HdR8HdT8HX0c3R39XX1CwHxAoJc3f0c_ZwjFcI9QzwUPP3cXJ1DPP1DgxUCHIE6fPzdI0HKQoP83V39PEMcfRRCghydQ3gYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSXxQqJGZiaWhkbmzoTERSgD1IC6s</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD OF MANAGEMENT OF PREGNANCY WITH INFECTIOUS PATHOLOGY OF UROGENITAL TRACT</title><source>esp@cenet</source><creator>Egorova Ekaterina Aleksandrovna ; Bajrakova Aleksandra Lvovna ; Metelskaya Valeriya Alekseevna ; Afanasev Stanislav Stepanovich ; Pylev Andrej Lvovich ; Nesvizhskij Yurij Vladimirovich ; Karaulov Aleksandr Viktorovich ; Borisova Olga Yurevna ; Bochkareva Svetlana Sergeevna ; Chesheva Vera Vasilevna ; Savchenko Tatyana Nikolaevna ; Voropaeva Elena Aleksandrovna ; Aleshkin Vladimir Andrianovich ; Aleshkin Andrej Vladimirovich ; Grechishnikova Olga Gennadievna ; Agaeva Madina Ilyasovna ; Voropaev Aleksandr Dmitrievich ; Tolstova Ekaterina Sergeevna ; Afanasev Maksim Stanislavovich ; Urban Yuliya Nikolaevna ; Zatevalov Aleksandr Mikhajlovich</creator><creatorcontrib>Egorova Ekaterina Aleksandrovna ; Bajrakova Aleksandra Lvovna ; Metelskaya Valeriya Alekseevna ; Afanasev Stanislav Stepanovich ; Pylev Andrej Lvovich ; Nesvizhskij Yurij Vladimirovich ; Karaulov Aleksandr Viktorovich ; Borisova Olga Yurevna ; Bochkareva Svetlana Sergeevna ; Chesheva Vera Vasilevna ; Savchenko Tatyana Nikolaevna ; Voropaeva Elena Aleksandrovna ; Aleshkin Vladimir Andrianovich ; Aleshkin Andrej Vladimirovich ; Grechishnikova Olga Gennadievna ; Agaeva Madina Ilyasovna ; Voropaev Aleksandr Dmitrievich ; Tolstova Ekaterina Sergeevna ; Afanasev Maksim Stanislavovich ; Urban Yuliya Nikolaevna ; Zatevalov Aleksandr Mikhajlovich</creatorcontrib><description>FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynecology, and may be used for management of pregnant women with an infectious pathology of the urogenital tract. To do this, the expression of the genes of the gamma gene of innate immunity - TLR, is examined. When establishing TLR-2 gene expression levels of 21.2 OE and above, TLR-4 23.0 OE and above, TLR-8 of 25.7 OE and above conduct emergency prophylaxis of abortion with prescription of vitamin therapy, antibiotic therapy, intravenous immunoglobulin and immunomodulator with antimicrobial activity. In this case, as an immunomodulator with antibacterial activity, kipferon can be used.EFFECT: method allows to achieve an adequate response to treatment by increasing the reliability of the prognosis of pregnancy during optimization of correction of management and treatment of pregnant women with an integrated assessment of the reactivity of the body and the course of pregnancy and prevention of complications of antibiotic therapy by clarifying the indications for its conduct by excluding it from a certain contingent of pregnant women.1 cl, 8 ex
Изобретение относится к медицине, а именно к акушерству и гинекологии, и может быть использовано для ведения беременных с инфекционной патологией урогенитального тракта. Для этого исследуют экспрессию генов рецепторов врожденного иммунитета - TLR. При установлении уровней экспрессии генов TLR-2 21,2 ОЕ и выше, TLR-4 23,0 ОЕ и выше, TLR-8 25,7 ОЕ и выше проводят экстренную профилактику прерывания беременности с назначением витаминотерапии, антибиотикотерапии, внутривенного иммуноглобулина и иммуномодулятора с антимикробной активностью. При этом в качестве иммуномодулятора с антибактериальной активностью может быть использован кипферон. Способ позволяет достичь адекватного ответа на лечение за счет повышения достоверности прогноза течения беременности при оптимизации коррекции ведения и лечения беременных с учетом интегральной оценки реактивности организма и течения беременности и профилактике осложнений антибактериальной терапии путем уточнения показаний к ее проведению за счет исключения ее проведения у определенного контингента беременных. 1 з.п. ф-лы, 8 пр.</description><language>eng ; rus</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180329&DB=EPODOC&CC=RU&NR=2649127C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180329&DB=EPODOC&CC=RU&NR=2649127C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Egorova Ekaterina Aleksandrovna</creatorcontrib><creatorcontrib>Bajrakova Aleksandra Lvovna</creatorcontrib><creatorcontrib>Metelskaya Valeriya Alekseevna</creatorcontrib><creatorcontrib>Afanasev Stanislav Stepanovich</creatorcontrib><creatorcontrib>Pylev Andrej Lvovich</creatorcontrib><creatorcontrib>Nesvizhskij Yurij Vladimirovich</creatorcontrib><creatorcontrib>Karaulov Aleksandr Viktorovich</creatorcontrib><creatorcontrib>Borisova Olga Yurevna</creatorcontrib><creatorcontrib>Bochkareva Svetlana Sergeevna</creatorcontrib><creatorcontrib>Chesheva Vera Vasilevna</creatorcontrib><creatorcontrib>Savchenko Tatyana Nikolaevna</creatorcontrib><creatorcontrib>Voropaeva Elena Aleksandrovna</creatorcontrib><creatorcontrib>Aleshkin Vladimir Andrianovich</creatorcontrib><creatorcontrib>Aleshkin Andrej Vladimirovich</creatorcontrib><creatorcontrib>Grechishnikova Olga Gennadievna</creatorcontrib><creatorcontrib>Agaeva Madina Ilyasovna</creatorcontrib><creatorcontrib>Voropaev Aleksandr Dmitrievich</creatorcontrib><creatorcontrib>Tolstova Ekaterina Sergeevna</creatorcontrib><creatorcontrib>Afanasev Maksim Stanislavovich</creatorcontrib><creatorcontrib>Urban Yuliya Nikolaevna</creatorcontrib><creatorcontrib>Zatevalov Aleksandr Mikhajlovich</creatorcontrib><title>METHOD OF MANAGEMENT OF PREGNANCY WITH INFECTIOUS PATHOLOGY OF UROGENITAL TRACT</title><description>FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynecology, and may be used for management of pregnant women with an infectious pathology of the urogenital tract. To do this, the expression of the genes of the gamma gene of innate immunity - TLR, is examined. When establishing TLR-2 gene expression levels of 21.2 OE and above, TLR-4 23.0 OE and above, TLR-8 of 25.7 OE and above conduct emergency prophylaxis of abortion with prescription of vitamin therapy, antibiotic therapy, intravenous immunoglobulin and immunomodulator with antimicrobial activity. In this case, as an immunomodulator with antibacterial activity, kipferon can be used.EFFECT: method allows to achieve an adequate response to treatment by increasing the reliability of the prognosis of pregnancy during optimization of correction of management and treatment of pregnant women with an integrated assessment of the reactivity of the body and the course of pregnancy and prevention of complications of antibiotic therapy by clarifying the indications for its conduct by excluding it from a certain contingent of pregnant women.1 cl, 8 ex
Изобретение относится к медицине, а именно к акушерству и гинекологии, и может быть использовано для ведения беременных с инфекционной патологией урогенитального тракта. Для этого исследуют экспрессию генов рецепторов врожденного иммунитета - TLR. При установлении уровней экспрессии генов TLR-2 21,2 ОЕ и выше, TLR-4 23,0 ОЕ и выше, TLR-8 25,7 ОЕ и выше проводят экстренную профилактику прерывания беременности с назначением витаминотерапии, антибиотикотерапии, внутривенного иммуноглобулина и иммуномодулятора с антимикробной активностью. При этом в качестве иммуномодулятора с антибактериальной активностью может быть использован кипферон. Способ позволяет достичь адекватного ответа на лечение за счет повышения достоверности прогноза течения беременности при оптимизации коррекции ведения и лечения беременных с учетом интегральной оценки реактивности организма и течения беременности и профилактике осложнений антибактериальной терапии путем уточнения показаний к ее проведению за счет исключения ее проведения у определенного контингента беременных. 1 з.п. ф-лы, 8 пр.</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPD3dQ3x8HdR8HdT8HX0c3R39XX1CwHxAoJc3f0c_ZwjFcI9QzwUPP3cXJ1DPP1DgxUCHIE6fPzdI0HKQoP83V39PEMcfRRCghydQ3gYWNMSc4pTeaE0N4OCm2uIs4duakF-fGpxQWJyal5qSXxQqJGZiaWhkbmzoTERSgD1IC6s</recordid><startdate>20180329</startdate><enddate>20180329</enddate><creator>Egorova Ekaterina Aleksandrovna</creator><creator>Bajrakova Aleksandra Lvovna</creator><creator>Metelskaya Valeriya Alekseevna</creator><creator>Afanasev Stanislav Stepanovich</creator><creator>Pylev Andrej Lvovich</creator><creator>Nesvizhskij Yurij Vladimirovich</creator><creator>Karaulov Aleksandr Viktorovich</creator><creator>Borisova Olga Yurevna</creator><creator>Bochkareva Svetlana Sergeevna</creator><creator>Chesheva Vera Vasilevna</creator><creator>Savchenko Tatyana Nikolaevna</creator><creator>Voropaeva Elena Aleksandrovna</creator><creator>Aleshkin Vladimir Andrianovich</creator><creator>Aleshkin Andrej Vladimirovich</creator><creator>Grechishnikova Olga Gennadievna</creator><creator>Agaeva Madina Ilyasovna</creator><creator>Voropaev Aleksandr Dmitrievich</creator><creator>Tolstova Ekaterina Sergeevna</creator><creator>Afanasev Maksim Stanislavovich</creator><creator>Urban Yuliya Nikolaevna</creator><creator>Zatevalov Aleksandr Mikhajlovich</creator><scope>EVB</scope></search><sort><creationdate>20180329</creationdate><title>METHOD OF MANAGEMENT OF PREGNANCY WITH INFECTIOUS PATHOLOGY OF UROGENITAL TRACT</title><author>Egorova Ekaterina Aleksandrovna ; Bajrakova Aleksandra Lvovna ; Metelskaya Valeriya Alekseevna ; Afanasev Stanislav Stepanovich ; Pylev Andrej Lvovich ; Nesvizhskij Yurij Vladimirovich ; Karaulov Aleksandr Viktorovich ; Borisova Olga Yurevna ; Bochkareva Svetlana Sergeevna ; Chesheva Vera Vasilevna ; Savchenko Tatyana Nikolaevna ; Voropaeva Elena Aleksandrovna ; Aleshkin Vladimir Andrianovich ; Aleshkin Andrej Vladimirovich ; Grechishnikova Olga Gennadievna ; Agaeva Madina Ilyasovna ; Voropaev Aleksandr Dmitrievich ; Tolstova Ekaterina Sergeevna ; Afanasev Maksim Stanislavovich ; Urban Yuliya Nikolaevna ; Zatevalov Aleksandr Mikhajlovich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2649127C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2018</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>Egorova Ekaterina Aleksandrovna</creatorcontrib><creatorcontrib>Bajrakova Aleksandra Lvovna</creatorcontrib><creatorcontrib>Metelskaya Valeriya Alekseevna</creatorcontrib><creatorcontrib>Afanasev Stanislav Stepanovich</creatorcontrib><creatorcontrib>Pylev Andrej Lvovich</creatorcontrib><creatorcontrib>Nesvizhskij Yurij Vladimirovich</creatorcontrib><creatorcontrib>Karaulov Aleksandr Viktorovich</creatorcontrib><creatorcontrib>Borisova Olga Yurevna</creatorcontrib><creatorcontrib>Bochkareva Svetlana Sergeevna</creatorcontrib><creatorcontrib>Chesheva Vera Vasilevna</creatorcontrib><creatorcontrib>Savchenko Tatyana Nikolaevna</creatorcontrib><creatorcontrib>Voropaeva Elena Aleksandrovna</creatorcontrib><creatorcontrib>Aleshkin Vladimir Andrianovich</creatorcontrib><creatorcontrib>Aleshkin Andrej Vladimirovich</creatorcontrib><creatorcontrib>Grechishnikova Olga Gennadievna</creatorcontrib><creatorcontrib>Agaeva Madina Ilyasovna</creatorcontrib><creatorcontrib>Voropaev Aleksandr Dmitrievich</creatorcontrib><creatorcontrib>Tolstova Ekaterina Sergeevna</creatorcontrib><creatorcontrib>Afanasev Maksim Stanislavovich</creatorcontrib><creatorcontrib>Urban Yuliya Nikolaevna</creatorcontrib><creatorcontrib>Zatevalov Aleksandr Mikhajlovich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Egorova Ekaterina Aleksandrovna</au><au>Bajrakova Aleksandra Lvovna</au><au>Metelskaya Valeriya Alekseevna</au><au>Afanasev Stanislav Stepanovich</au><au>Pylev Andrej Lvovich</au><au>Nesvizhskij Yurij Vladimirovich</au><au>Karaulov Aleksandr Viktorovich</au><au>Borisova Olga Yurevna</au><au>Bochkareva Svetlana Sergeevna</au><au>Chesheva Vera Vasilevna</au><au>Savchenko Tatyana Nikolaevna</au><au>Voropaeva Elena Aleksandrovna</au><au>Aleshkin Vladimir Andrianovich</au><au>Aleshkin Andrej Vladimirovich</au><au>Grechishnikova Olga Gennadievna</au><au>Agaeva Madina Ilyasovna</au><au>Voropaev Aleksandr Dmitrievich</au><au>Tolstova Ekaterina Sergeevna</au><au>Afanasev Maksim Stanislavovich</au><au>Urban Yuliya Nikolaevna</au><au>Zatevalov Aleksandr Mikhajlovich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF MANAGEMENT OF PREGNANCY WITH INFECTIOUS PATHOLOGY OF UROGENITAL TRACT</title><date>2018-03-29</date><risdate>2018</risdate><abstract>FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynecology, and may be used for management of pregnant women with an infectious pathology of the urogenital tract. To do this, the expression of the genes of the gamma gene of innate immunity - TLR, is examined. When establishing TLR-2 gene expression levels of 21.2 OE and above, TLR-4 23.0 OE and above, TLR-8 of 25.7 OE and above conduct emergency prophylaxis of abortion with prescription of vitamin therapy, antibiotic therapy, intravenous immunoglobulin and immunomodulator with antimicrobial activity. In this case, as an immunomodulator with antibacterial activity, kipferon can be used.EFFECT: method allows to achieve an adequate response to treatment by increasing the reliability of the prognosis of pregnancy during optimization of correction of management and treatment of pregnant women with an integrated assessment of the reactivity of the body and the course of pregnancy and prevention of complications of antibiotic therapy by clarifying the indications for its conduct by excluding it from a certain contingent of pregnant women.1 cl, 8 ex
Изобретение относится к медицине, а именно к акушерству и гинекологии, и может быть использовано для ведения беременных с инфекционной патологией урогенитального тракта. Для этого исследуют экспрессию генов рецепторов врожденного иммунитета - TLR. При установлении уровней экспрессии генов TLR-2 21,2 ОЕ и выше, TLR-4 23,0 ОЕ и выше, TLR-8 25,7 ОЕ и выше проводят экстренную профилактику прерывания беременности с назначением витаминотерапии, антибиотикотерапии, внутривенного иммуноглобулина и иммуномодулятора с антимикробной активностью. При этом в качестве иммуномодулятора с антибактериальной активностью может быть использован кипферон. Способ позволяет достичь адекватного ответа на лечение за счет повышения достоверности прогноза течения беременности при оптимизации коррекции ведения и лечения беременных с учетом интегральной оценки реактивности организма и течения беременности и профилактике осложнений антибактериальной терапии путем уточнения показаний к ее проведению за счет исключения ее проведения у определенного контингента беременных. 1 з.п. ф-лы, 8 пр.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2649127C1 |
| source | esp@cenet |
| subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
| title | METHOD OF MANAGEMENT OF PREGNANCY WITH INFECTIOUS PATHOLOGY OF UROGENITAL TRACT |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T10%3A17%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Egorova%20Ekaterina%20Aleksandrovna&rft.date=2018-03-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2649127C1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |