NEW PHTHALAZINE DERIVATIVES AND ITS PRODUCTION PROCESS
FIELD: pharmacology.SUBSTANCE: invention relates to the phthalazine derivatives that are represented by the formula I,where the radicals and symbols have the definitions indicated in the formula of the invention. The compounds of the formula I are activity inhibitors of the poly(ADP-ribose) polymera...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LI Yun-Sok KIM Chon-Kyn KHON Chan-Khe PAK Son-Yun AN Ken-Mi YUN En-Ton LI Khon-Sop CHON Chin-A KIM Ken-Son PAK Chun-Tkhe SON Ton-Kon KAN Che-Khun |
| description | FIELD: pharmacology.SUBSTANCE: invention relates to the phthalazine derivatives that are represented by the formula I,where the radicals and symbols have the definitions indicated in the formula of the invention. The compounds of the formula I are activity inhibitors of the poly(ADP-ribose) polymerase ferment. The invention also relates to the pharmaceutical composition for cancer treatment, which comprises the compound of the formula I, to the method of cancer treatment and to the compound application for the medicinal agent for cancer treatment production.EFFECT: compound application efficiency upgrading.16 cl, 8 tbl, 176 ex
Настоящее изобретение касается фталазиноновых производных, представленных формулой I, в которой радикалы и символы имеют определения, указанные в формуле изобретения. Соединения формулы I являются ингибиторами активности поли(АДФ-рибозид) полимеразного фермента. Изобретение также относится к фармацевтической композиции для лечения рака, содержащей соединение формулы I, способу лечения рака и применению соединения для изготовления лекарственного средства для лечения рака. 4 н. и 12 з.п. ф-лы, 8 табл., 176 пр.Формула I |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2636585C2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2636585C2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2636585C23</originalsourceid><addsrcrecordid>eNrjZDDzcw1XCPAI8XD0cYzy9HNVcHEN8gxzDPEMcw1WcPRzUfAMCVYICPJ3CXUO8fT3AzGdXYODeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfFCokZmxmamFqbORMRFKAOp1KAY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NEW PHTHALAZINE DERIVATIVES AND ITS PRODUCTION PROCESS</title><source>esp@cenet</source><creator>LI Yun-Sok ; KIM Chon-Kyn ; KHON Chan-Khe ; PAK Son-Yun ; AN Ken-Mi ; YUN En-Ton ; LI Khon-Sop ; CHON Chin-A ; KIM Ken-Son ; PAK Chun-Tkhe ; SON Ton-Kon ; KAN Che-Khun</creator><creatorcontrib>LI Yun-Sok ; KIM Chon-Kyn ; KHON Chan-Khe ; PAK Son-Yun ; AN Ken-Mi ; YUN En-Ton ; LI Khon-Sop ; CHON Chin-A ; KIM Ken-Son ; PAK Chun-Tkhe ; SON Ton-Kon ; KAN Che-Khun</creatorcontrib><description>FIELD: pharmacology.SUBSTANCE: invention relates to the phthalazine derivatives that are represented by the formula I,where the radicals and symbols have the definitions indicated in the formula of the invention. The compounds of the formula I are activity inhibitors of the poly(ADP-ribose) polymerase ferment. The invention also relates to the pharmaceutical composition for cancer treatment, which comprises the compound of the formula I, to the method of cancer treatment and to the compound application for the medicinal agent for cancer treatment production.EFFECT: compound application efficiency upgrading.16 cl, 8 tbl, 176 ex
Настоящее изобретение касается фталазиноновых производных, представленных формулой I, в которой радикалы и символы имеют определения, указанные в формуле изобретения. Соединения формулы I являются ингибиторами активности поли(АДФ-рибозид) полимеразного фермента. Изобретение также относится к фармацевтической композиции для лечения рака, содержащей соединение формулы I, способу лечения рака и применению соединения для изготовления лекарственного средства для лечения рака. 4 н. и 12 з.п. ф-лы, 8 табл., 176 пр.Формула I</description><language>eng ; rus</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171124&DB=EPODOC&CC=RU&NR=2636585C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171124&DB=EPODOC&CC=RU&NR=2636585C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI Yun-Sok</creatorcontrib><creatorcontrib>KIM Chon-Kyn</creatorcontrib><creatorcontrib>KHON Chan-Khe</creatorcontrib><creatorcontrib>PAK Son-Yun</creatorcontrib><creatorcontrib>AN Ken-Mi</creatorcontrib><creatorcontrib>YUN En-Ton</creatorcontrib><creatorcontrib>LI Khon-Sop</creatorcontrib><creatorcontrib>CHON Chin-A</creatorcontrib><creatorcontrib>KIM Ken-Son</creatorcontrib><creatorcontrib>PAK Chun-Tkhe</creatorcontrib><creatorcontrib>SON Ton-Kon</creatorcontrib><creatorcontrib>KAN Che-Khun</creatorcontrib><title>NEW PHTHALAZINE DERIVATIVES AND ITS PRODUCTION PROCESS</title><description>FIELD: pharmacology.SUBSTANCE: invention relates to the phthalazine derivatives that are represented by the formula I,where the radicals and symbols have the definitions indicated in the formula of the invention. The compounds of the formula I are activity inhibitors of the poly(ADP-ribose) polymerase ferment. The invention also relates to the pharmaceutical composition for cancer treatment, which comprises the compound of the formula I, to the method of cancer treatment and to the compound application for the medicinal agent for cancer treatment production.EFFECT: compound application efficiency upgrading.16 cl, 8 tbl, 176 ex
Настоящее изобретение касается фталазиноновых производных, представленных формулой I, в которой радикалы и символы имеют определения, указанные в формуле изобретения. Соединения формулы I являются ингибиторами активности поли(АДФ-рибозид) полимеразного фермента. Изобретение также относится к фармацевтической композиции для лечения рака, содержащей соединение формулы I, способу лечения рака и применению соединения для изготовления лекарственного средства для лечения рака. 4 н. и 12 з.п. ф-лы, 8 табл., 176 пр.Формула I</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDzcw1XCPAI8XD0cYzy9HNVcHEN8gxzDPEMcw1WcPRzUfAMCVYICPJ3CXUO8fT3AzGdXYODeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfFCokZmxmamFqbORMRFKAOp1KAY</recordid><startdate>20171124</startdate><enddate>20171124</enddate><creator>LI Yun-Sok</creator><creator>KIM Chon-Kyn</creator><creator>KHON Chan-Khe</creator><creator>PAK Son-Yun</creator><creator>AN Ken-Mi</creator><creator>YUN En-Ton</creator><creator>LI Khon-Sop</creator><creator>CHON Chin-A</creator><creator>KIM Ken-Son</creator><creator>PAK Chun-Tkhe</creator><creator>SON Ton-Kon</creator><creator>KAN Che-Khun</creator><scope>EVB</scope></search><sort><creationdate>20171124</creationdate><title>NEW PHTHALAZINE DERIVATIVES AND ITS PRODUCTION PROCESS</title><author>LI Yun-Sok ; KIM Chon-Kyn ; KHON Chan-Khe ; PAK Son-Yun ; AN Ken-Mi ; YUN En-Ton ; LI Khon-Sop ; CHON Chin-A ; KIM Ken-Son ; PAK Chun-Tkhe ; SON Ton-Kon ; KAN Che-Khun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2636585C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LI Yun-Sok</creatorcontrib><creatorcontrib>KIM Chon-Kyn</creatorcontrib><creatorcontrib>KHON Chan-Khe</creatorcontrib><creatorcontrib>PAK Son-Yun</creatorcontrib><creatorcontrib>AN Ken-Mi</creatorcontrib><creatorcontrib>YUN En-Ton</creatorcontrib><creatorcontrib>LI Khon-Sop</creatorcontrib><creatorcontrib>CHON Chin-A</creatorcontrib><creatorcontrib>KIM Ken-Son</creatorcontrib><creatorcontrib>PAK Chun-Tkhe</creatorcontrib><creatorcontrib>SON Ton-Kon</creatorcontrib><creatorcontrib>KAN Che-Khun</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI Yun-Sok</au><au>KIM Chon-Kyn</au><au>KHON Chan-Khe</au><au>PAK Son-Yun</au><au>AN Ken-Mi</au><au>YUN En-Ton</au><au>LI Khon-Sop</au><au>CHON Chin-A</au><au>KIM Ken-Son</au><au>PAK Chun-Tkhe</au><au>SON Ton-Kon</au><au>KAN Che-Khun</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NEW PHTHALAZINE DERIVATIVES AND ITS PRODUCTION PROCESS</title><date>2017-11-24</date><risdate>2017</risdate><abstract>FIELD: pharmacology.SUBSTANCE: invention relates to the phthalazine derivatives that are represented by the formula I,where the radicals and symbols have the definitions indicated in the formula of the invention. The compounds of the formula I are activity inhibitors of the poly(ADP-ribose) polymerase ferment. The invention also relates to the pharmaceutical composition for cancer treatment, which comprises the compound of the formula I, to the method of cancer treatment and to the compound application for the medicinal agent for cancer treatment production.EFFECT: compound application efficiency upgrading.16 cl, 8 tbl, 176 ex
Настоящее изобретение касается фталазиноновых производных, представленных формулой I, в которой радикалы и символы имеют определения, указанные в формуле изобретения. Соединения формулы I являются ингибиторами активности поли(АДФ-рибозид) полимеразного фермента. Изобретение также относится к фармацевтической композиции для лечения рака, содержащей соединение формулы I, способу лечения рака и применению соединения для изготовления лекарственного средства для лечения рака. 4 н. и 12 з.п. ф-лы, 8 табл., 176 пр.Формула I</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2636585C2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NEW PHTHALAZINE DERIVATIVES AND ITS PRODUCTION PROCESS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T04%3A40%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LI%20Yun-Sok&rft.date=2017-11-24&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2636585C2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |