FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA
FIELD: biotechnology.SUBSTANCE: invention relates to novel peptide structures having antibacterial properties and can be used in medicine. A family of peptides having inhibitory activity against bacterial RecA proteins is claimed, as well as having the property of blocking the SOS-response of bacter...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Khodorkovskij Mikhail Alekseevich Bajtin Dmitrij Mikhajlovich Pobegalov Georgij Evgenevich Yakimov Aleksandr Pavlovich Bakhlanova Irina Vitalevna Petukhov Mikhail Gennadievich |
| description | FIELD: biotechnology.SUBSTANCE: invention relates to novel peptide structures having antibacterial properties and can be used in medicine. A family of peptides having inhibitory activity against bacterial RecA proteins is claimed, as well as having the property of blocking the SOS-response of bacteria.EFFECT: unlike the known analogs, the proposed peptides have greater conformational stability and are able to inhibit the activity of RecA protein with a sufficiently lowIC.4 ex, 1 tbl, 5 dwg
Изобретение относится к области биотехнологии, конкретно к новым пептидным структурам, обладающим антибактериальными свойствами, и может быть использовано в медицине. Заявляется семейство пептидов, обладающих ингибирующей активностью против бактериальных белков RecA, а также свойством блокирования SOS-ответа у бактерий. В отличие от известных аналогов предложенные пептиды обладают большей конформационной стабильностью и способны ингибировать активность белка RecA с достаточно низким IC. 4 пр., 1 табл., 5 ил. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2621862C1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2621862C1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2621862C13</originalsourceid><addsrcrecordid>eNqNyjEKwjAUgOEuDqLe4R3ADI1QXJP4Yh_WJOSlQnEoReIkWqj3RwsewOkf_m9ZXK06U9OBtxAwJDoggwByNWlKPvI8IhoFIfqE5ECZRBdK3RZ0482J3BHYs4jIwTvG2euvwUhqXSzuw2PKm19XBVhMphZ5fPV5GodbfuZ3H1tZyXJfSVPu_iAf9LUxeQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA</title><source>esp@cenet</source><creator>Khodorkovskij Mikhail Alekseevich ; Bajtin Dmitrij Mikhajlovich ; Pobegalov Georgij Evgenevich ; Yakimov Aleksandr Pavlovich ; Bakhlanova Irina Vitalevna ; Petukhov Mikhail Gennadievich</creator><creatorcontrib>Khodorkovskij Mikhail Alekseevich ; Bajtin Dmitrij Mikhajlovich ; Pobegalov Georgij Evgenevich ; Yakimov Aleksandr Pavlovich ; Bakhlanova Irina Vitalevna ; Petukhov Mikhail Gennadievich</creatorcontrib><description>FIELD: biotechnology.SUBSTANCE: invention relates to novel peptide structures having antibacterial properties and can be used in medicine. A family of peptides having inhibitory activity against bacterial RecA proteins is claimed, as well as having the property of blocking the SOS-response of bacteria.EFFECT: unlike the known analogs, the proposed peptides have greater conformational stability and are able to inhibit the activity of RecA protein with a sufficiently lowIC.4 ex, 1 tbl, 5 dwg
Изобретение относится к области биотехнологии, конкретно к новым пептидным структурам, обладающим антибактериальными свойствами, и может быть использовано в медицине. Заявляется семейство пептидов, обладающих ингибирующей активностью против бактериальных белков RecA, а также свойством блокирования SOS-ответа у бактерий. В отличие от известных аналогов предложенные пептиды обладают большей конформационной стабильностью и способны ингибировать активность белка RecA с достаточно низким IC. 4 пр., 1 табл., 5 ил.</description><language>eng ; rus</language><subject>CHEMISTRY ; COMBINATORIAL CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170607&DB=EPODOC&CC=RU&NR=2621862C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170607&DB=EPODOC&CC=RU&NR=2621862C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Khodorkovskij Mikhail Alekseevich</creatorcontrib><creatorcontrib>Bajtin Dmitrij Mikhajlovich</creatorcontrib><creatorcontrib>Pobegalov Georgij Evgenevich</creatorcontrib><creatorcontrib>Yakimov Aleksandr Pavlovich</creatorcontrib><creatorcontrib>Bakhlanova Irina Vitalevna</creatorcontrib><creatorcontrib>Petukhov Mikhail Gennadievich</creatorcontrib><title>FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA</title><description>FIELD: biotechnology.SUBSTANCE: invention relates to novel peptide structures having antibacterial properties and can be used in medicine. A family of peptides having inhibitory activity against bacterial RecA proteins is claimed, as well as having the property of blocking the SOS-response of bacteria.EFFECT: unlike the known analogs, the proposed peptides have greater conformational stability and are able to inhibit the activity of RecA protein with a sufficiently lowIC.4 ex, 1 tbl, 5 dwg
Изобретение относится к области биотехнологии, конкретно к новым пептидным структурам, обладающим антибактериальными свойствами, и может быть использовано в медицине. Заявляется семейство пептидов, обладающих ингибирующей активностью против бактериальных белков RecA, а также свойством блокирования SOS-ответа у бактерий. В отличие от известных аналогов предложенные пептиды обладают большей конформационной стабильностью и способны ингибировать активность белка RecA с достаточно низким IC. 4 пр., 1 табл., 5 ил.</description><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEKwjAUgOEuDqLe4R3ADI1QXJP4Yh_WJOSlQnEoReIkWqj3RwsewOkf_m9ZXK06U9OBtxAwJDoggwByNWlKPvI8IhoFIfqE5ECZRBdK3RZ0482J3BHYs4jIwTvG2euvwUhqXSzuw2PKm19XBVhMphZ5fPV5GodbfuZ3H1tZyXJfSVPu_iAf9LUxeQ</recordid><startdate>20170607</startdate><enddate>20170607</enddate><creator>Khodorkovskij Mikhail Alekseevich</creator><creator>Bajtin Dmitrij Mikhajlovich</creator><creator>Pobegalov Georgij Evgenevich</creator><creator>Yakimov Aleksandr Pavlovich</creator><creator>Bakhlanova Irina Vitalevna</creator><creator>Petukhov Mikhail Gennadievich</creator><scope>EVB</scope></search><sort><creationdate>20170607</creationdate><title>FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA</title><author>Khodorkovskij Mikhail Alekseevich ; Bajtin Dmitrij Mikhajlovich ; Pobegalov Georgij Evgenevich ; Yakimov Aleksandr Pavlovich ; Bakhlanova Irina Vitalevna ; Petukhov Mikhail Gennadievich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2621862C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Khodorkovskij Mikhail Alekseevich</creatorcontrib><creatorcontrib>Bajtin Dmitrij Mikhajlovich</creatorcontrib><creatorcontrib>Pobegalov Georgij Evgenevich</creatorcontrib><creatorcontrib>Yakimov Aleksandr Pavlovich</creatorcontrib><creatorcontrib>Bakhlanova Irina Vitalevna</creatorcontrib><creatorcontrib>Petukhov Mikhail Gennadievich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Khodorkovskij Mikhail Alekseevich</au><au>Bajtin Dmitrij Mikhajlovich</au><au>Pobegalov Georgij Evgenevich</au><au>Yakimov Aleksandr Pavlovich</au><au>Bakhlanova Irina Vitalevna</au><au>Petukhov Mikhail Gennadievich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA</title><date>2017-06-07</date><risdate>2017</risdate><abstract>FIELD: biotechnology.SUBSTANCE: invention relates to novel peptide structures having antibacterial properties and can be used in medicine. A family of peptides having inhibitory activity against bacterial RecA proteins is claimed, as well as having the property of blocking the SOS-response of bacteria.EFFECT: unlike the known analogs, the proposed peptides have greater conformational stability and are able to inhibit the activity of RecA protein with a sufficiently lowIC.4 ex, 1 tbl, 5 dwg
Изобретение относится к области биотехнологии, конкретно к новым пептидным структурам, обладающим антибактериальными свойствами, и может быть использовано в медицине. Заявляется семейство пептидов, обладающих ингибирующей активностью против бактериальных белков RecA, а также свойством блокирования SOS-ответа у бактерий. В отличие от известных аналогов предложенные пептиды обладают большей конформационной стабильностью и способны ингибировать активность белка RecA с достаточно низким IC. 4 пр., 1 табл., 5 ил.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2621862C1 |
| source | esp@cenet |
| subjects | CHEMISTRY COMBINATORIAL CHEMISTRY HUMAN NECESSITIES HYGIENE LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T11%3A41%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Khodorkovskij%20Mikhail%20Alekseevich&rft.date=2017-06-07&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2621862C1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |