NEW INDANSULFAMIDNOE DERIVATIVES
FIELD: chemistry.SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | VATANABE Toru KOSASA Takasi KHANADA Takakhisa ISIKAVA Yukio SAITO Minako KITA Joiti SORIMATI Keiiti TANAKA Tosiaki TERAMOTO Tetsuyuki KADZUTA Yudzi KHIGASIYAMA Khiroyuki |
| description | FIELD: chemistry.SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, are characterized by the effect of improving seizure severity index (score) in a murine model of kindling.EFFECT: compound or salt thereof are assumed as a medicament for the treatment of epilepsy.8 cl, 10 tbl, 3 dwg, 31 ex
Новые индансульфамидные производные, или их фармацевтически приемлемая соль, такие как N-[(1S)-2,2,5,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, N-[(1S)-2,2,4,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, (+)-N-(2,2,4,6,7-пентафтор-2,3-дигидро-1H-инден-1-ил)сульфамид, характеризуются действием улучшения индекса тяжести припадка (балл) на мышиной модели киндлинга. Таким образом, соединения или их соль предполагаются в качестве лекарственного средства для лечения эпилепсии. 8 н.п. ф-лы, 10 табл., 3 ил., 31 пр. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2619937C2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2619937C2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2619937C23</originalsourceid><addsrcrecordid>eNrjZFDwcw1X8PRzcfQLDvVxc_T1dPHzd1VwcQ3yDHMM8QxzDeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfFBoUZmhpaWxubORsZEKAEAzwgh9A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NEW INDANSULFAMIDNOE DERIVATIVES</title><source>esp@cenet</source><creator>VATANABE Toru ; KOSASA Takasi ; KHANADA Takakhisa ; ISIKAVA Yukio ; SAITO Minako ; KITA Joiti ; SORIMATI Keiiti ; TANAKA Tosiaki ; TERAMOTO Tetsuyuki ; KADZUTA Yudzi ; KHIGASIYAMA Khiroyuki</creator><creatorcontrib>VATANABE Toru ; KOSASA Takasi ; KHANADA Takakhisa ; ISIKAVA Yukio ; SAITO Minako ; KITA Joiti ; SORIMATI Keiiti ; TANAKA Tosiaki ; TERAMOTO Tetsuyuki ; KADZUTA Yudzi ; KHIGASIYAMA Khiroyuki</creatorcontrib><description>FIELD: chemistry.SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, are characterized by the effect of improving seizure severity index (score) in a murine model of kindling.EFFECT: compound or salt thereof are assumed as a medicament for the treatment of epilepsy.8 cl, 10 tbl, 3 dwg, 31 ex
Новые индансульфамидные производные, или их фармацевтически приемлемая соль, такие как N-[(1S)-2,2,5,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, N-[(1S)-2,2,4,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, (+)-N-(2,2,4,6,7-пентафтор-2,3-дигидро-1H-инден-1-ил)сульфамид, характеризуются действием улучшения индекса тяжести припадка (балл) на мышиной модели киндлинга. Таким образом, соединения или их соль предполагаются в качестве лекарственного средства для лечения эпилепсии. 8 н.п. ф-лы, 10 табл., 3 ил., 31 пр.</description><language>eng ; rus</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170522&DB=EPODOC&CC=RU&NR=2619937C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170522&DB=EPODOC&CC=RU&NR=2619937C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VATANABE Toru</creatorcontrib><creatorcontrib>KOSASA Takasi</creatorcontrib><creatorcontrib>KHANADA Takakhisa</creatorcontrib><creatorcontrib>ISIKAVA Yukio</creatorcontrib><creatorcontrib>SAITO Minako</creatorcontrib><creatorcontrib>KITA Joiti</creatorcontrib><creatorcontrib>SORIMATI Keiiti</creatorcontrib><creatorcontrib>TANAKA Tosiaki</creatorcontrib><creatorcontrib>TERAMOTO Tetsuyuki</creatorcontrib><creatorcontrib>KADZUTA Yudzi</creatorcontrib><creatorcontrib>KHIGASIYAMA Khiroyuki</creatorcontrib><title>NEW INDANSULFAMIDNOE DERIVATIVES</title><description>FIELD: chemistry.SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, are characterized by the effect of improving seizure severity index (score) in a murine model of kindling.EFFECT: compound or salt thereof are assumed as a medicament for the treatment of epilepsy.8 cl, 10 tbl, 3 dwg, 31 ex
Новые индансульфамидные производные, или их фармацевтически приемлемая соль, такие как N-[(1S)-2,2,5,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, N-[(1S)-2,2,4,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, (+)-N-(2,2,4,6,7-пентафтор-2,3-дигидро-1H-инден-1-ил)сульфамид, характеризуются действием улучшения индекса тяжести припадка (балл) на мышиной модели киндлинга. Таким образом, соединения или их соль предполагаются в качестве лекарственного средства для лечения эпилепсии. 8 н.п. ф-лы, 10 табл., 3 ил., 31 пр.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFDwcw1X8PRzcfQLDvVxc_T1dPHzd1VwcQ3yDHMM8QxzDeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfFBoUZmhpaWxubORsZEKAEAzwgh9A</recordid><startdate>20170522</startdate><enddate>20170522</enddate><creator>VATANABE Toru</creator><creator>KOSASA Takasi</creator><creator>KHANADA Takakhisa</creator><creator>ISIKAVA Yukio</creator><creator>SAITO Minako</creator><creator>KITA Joiti</creator><creator>SORIMATI Keiiti</creator><creator>TANAKA Tosiaki</creator><creator>TERAMOTO Tetsuyuki</creator><creator>KADZUTA Yudzi</creator><creator>KHIGASIYAMA Khiroyuki</creator><scope>EVB</scope></search><sort><creationdate>20170522</creationdate><title>NEW INDANSULFAMIDNOE DERIVATIVES</title><author>VATANABE Toru ; KOSASA Takasi ; KHANADA Takakhisa ; ISIKAVA Yukio ; SAITO Minako ; KITA Joiti ; SORIMATI Keiiti ; TANAKA Tosiaki ; TERAMOTO Tetsuyuki ; KADZUTA Yudzi ; KHIGASIYAMA Khiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2619937C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2017</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>VATANABE Toru</creatorcontrib><creatorcontrib>KOSASA Takasi</creatorcontrib><creatorcontrib>KHANADA Takakhisa</creatorcontrib><creatorcontrib>ISIKAVA Yukio</creatorcontrib><creatorcontrib>SAITO Minako</creatorcontrib><creatorcontrib>KITA Joiti</creatorcontrib><creatorcontrib>SORIMATI Keiiti</creatorcontrib><creatorcontrib>TANAKA Tosiaki</creatorcontrib><creatorcontrib>TERAMOTO Tetsuyuki</creatorcontrib><creatorcontrib>KADZUTA Yudzi</creatorcontrib><creatorcontrib>KHIGASIYAMA Khiroyuki</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>VATANABE Toru</au><au>KOSASA Takasi</au><au>KHANADA Takakhisa</au><au>ISIKAVA Yukio</au><au>SAITO Minako</au><au>KITA Joiti</au><au>SORIMATI Keiiti</au><au>TANAKA Tosiaki</au><au>TERAMOTO Tetsuyuki</au><au>KADZUTA Yudzi</au><au>KHIGASIYAMA Khiroyuki</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NEW INDANSULFAMIDNOE DERIVATIVES</title><date>2017-05-22</date><risdate>2017</risdate><abstract>FIELD: chemistry.SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, are characterized by the effect of improving seizure severity index (score) in a murine model of kindling.EFFECT: compound or salt thereof are assumed as a medicament for the treatment of epilepsy.8 cl, 10 tbl, 3 dwg, 31 ex
Новые индансульфамидные производные, или их фармацевтически приемлемая соль, такие как N-[(1S)-2,2,5,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, N-[(1S)-2,2,4,7-тетрафтор-2,3-дигидро-1H-инден-1-ил]сульфамид, (+)-N-(2,2,4,6,7-пентафтор-2,3-дигидро-1H-инден-1-ил)сульфамид, характеризуются действием улучшения индекса тяжести припадка (балл) на мышиной модели киндлинга. Таким образом, соединения или их соль предполагаются в качестве лекарственного средства для лечения эпилепсии. 8 н.п. ф-лы, 10 табл., 3 ил., 31 пр.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2619937C2 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NEW INDANSULFAMIDNOE DERIVATIVES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T15%3A27%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=VATANABE%20Toru&rft.date=2017-05-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2619937C2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |