METHOD FOR TROPHOBLAST CELLS BIOPSY AT MULTIPLICITY OF CELLS THAT DO NOT PARTICIPATE IN COMPACTION AT BLASTOCYST STAGE FOR HUMAN EMBRYOS PREIMPLANTATION GENETIC SCREENING PROGRAMMES

FIELD: medicine.SUBSTANCE: for trophoblast cells biopsy in human embryos preimplantation genetic screening programs, blastocysts pellucid zone is completely removed in the presence of multiple cells that do not participate in compaction. Trophoblast cells are freed, biopsy is performed not including...

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Hauptverfasser: Smolnikova Veronika Yurevna, Sukhikh Gennadij Tikhonovich, Kalinina Elena Anatolevna, Dolgushina Nataliya Vitalevna, Makarova Natalya Petrovna
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creator Smolnikova Veronika Yurevna
Sukhikh Gennadij Tikhonovich
Kalinina Elena Anatolevna
Dolgushina Nataliya Vitalevna
Makarova Natalya Petrovna
description FIELD: medicine.SUBSTANCE: for trophoblast cells biopsy in human embryos preimplantation genetic screening programs, blastocysts pellucid zone is completely removed in the presence of multiple cells that do not participate in compaction. Trophoblast cells are freed, biopsy is performed not including the cells that are not involved in compaction into the material transferred to genetic diagnosis.EFFECT: method allows to obtain biopsy material of good quality due to the complete removal of the pellucid zone.2 ex Изобретение относится к области медицины, а именно к гинекологии, репродуктологии и клинической эмбриологии. Для биопсии клеток трофобласта в программах преимплантационного генетического скрининга эмбрионов человека, бластоцистам при наличии множественных клеток, не участвующих в компактизации, полностью удаляют зону пеллюцида. Освобождают клетки трофобласта, проводят биопсию и не включают клетки, не участвующие в компактизации, в материал, передаваемый на генетическую диагностику. Способ позволяет получить биопсийный материал хорошего качества за счет полного удаления зоны пеллюцида. 2 пр.
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subjects DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
SURGERY
title METHOD FOR TROPHOBLAST CELLS BIOPSY AT MULTIPLICITY OF CELLS THAT DO NOT PARTICIPATE IN COMPACTION AT BLASTOCYST STAGE FOR HUMAN EMBRYOS PREIMPLANTATION GENETIC SCREENING PROGRAMMES
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