METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM

FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Avtina Valentina Valerevna, Losenok Polina Igorevna, Bogachev Ilja Aleksandrovich, Denisjuk Tatjana Alekseevna, Grigorenko Aleksandr Petrovich, Sarojan Karen Vanushovich, Pokrovskij Mikhail Vladimirovich, Krolevets Aleksandr Aleksandrovich, Sitnik Mikhail Vladimirovich
Format: Patent
Sprache:eng ; rus
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Avtina Valentina Valerevna
Losenok Polina Igorevna
Bogachev Ilja Aleksandrovich
Denisjuk Tatjana Alekseevna
Grigorenko Aleksandr Petrovich
Sarojan Karen Vanushovich
Pokrovskij Mikhail Vladimirovich
Krolevets Aleksandr Aleksandrovich
Sitnik Mikhail Vladimirovich
description FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2605847C2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2605847C2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2605847C23</originalsourceid><addsrcrecordid>eNrjZLDzdQ3x8HdR8HdTCAjydwl19vRzV_Bz9PN3dgwIDvVxDQbJBPkHh4Y5Boc4hnj6KQCRt7-fl6OzgnuoLw8Da1piTnEqL5TmZlBwcw1x9tBNLciPTy0uSExOzUstiQ8KNTIzMLUwMXc2MiZCCQAZSioC</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><source>esp@cenet</source><creator>Avtina Valentina Valerevna ; Losenok Polina Igorevna ; Bogachev Ilja Aleksandrovich ; Denisjuk Tatjana Alekseevna ; Grigorenko Aleksandr Petrovich ; Sarojan Karen Vanushovich ; Pokrovskij Mikhail Vladimirovich ; Krolevets Aleksandr Aleksandrovich ; Sitnik Mikhail Vladimirovich</creator><creatorcontrib>Avtina Valentina Valerevna ; Losenok Polina Igorevna ; Bogachev Ilja Aleksandrovich ; Denisjuk Tatjana Alekseevna ; Grigorenko Aleksandr Petrovich ; Sarojan Karen Vanushovich ; Pokrovskij Mikhail Vladimirovich ; Krolevets Aleksandr Aleksandrovich ; Sitnik Mikhail Vladimirovich</creatorcontrib><description>FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.</description><language>eng ; rus</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MANUFACTURE OR TREATMENT THEREOF ; MEDICAL OR VETERINARY SCIENCE ; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS ; NANOTECHNOLOGY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20161227&amp;DB=EPODOC&amp;CC=RU&amp;NR=2605847C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20161227&amp;DB=EPODOC&amp;CC=RU&amp;NR=2605847C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Avtina Valentina Valerevna</creatorcontrib><creatorcontrib>Losenok Polina Igorevna</creatorcontrib><creatorcontrib>Bogachev Ilja Aleksandrovich</creatorcontrib><creatorcontrib>Denisjuk Tatjana Alekseevna</creatorcontrib><creatorcontrib>Grigorenko Aleksandr Petrovich</creatorcontrib><creatorcontrib>Sarojan Karen Vanushovich</creatorcontrib><creatorcontrib>Pokrovskij Mikhail Vladimirovich</creatorcontrib><creatorcontrib>Krolevets Aleksandr Aleksandrovich</creatorcontrib><creatorcontrib>Sitnik Mikhail Vladimirovich</creatorcontrib><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><description>FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MANUFACTURE OR TREATMENT THEREOF</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS</subject><subject>NANOTECHNOLOGY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDzdQ3x8HdR8HdTCAjydwl19vRzV_Bz9PN3dgwIDvVxDQbJBPkHh4Y5Boc4hnj6KQCRt7-fl6OzgnuoLw8Da1piTnEqL5TmZlBwcw1x9tBNLciPTy0uSExOzUstiQ8KNTIzMLUwMXc2MiZCCQAZSioC</recordid><startdate>20161227</startdate><enddate>20161227</enddate><creator>Avtina Valentina Valerevna</creator><creator>Losenok Polina Igorevna</creator><creator>Bogachev Ilja Aleksandrovich</creator><creator>Denisjuk Tatjana Alekseevna</creator><creator>Grigorenko Aleksandr Petrovich</creator><creator>Sarojan Karen Vanushovich</creator><creator>Pokrovskij Mikhail Vladimirovich</creator><creator>Krolevets Aleksandr Aleksandrovich</creator><creator>Sitnik Mikhail Vladimirovich</creator><scope>EVB</scope></search><sort><creationdate>20161227</creationdate><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><author>Avtina Valentina Valerevna ; Losenok Polina Igorevna ; Bogachev Ilja Aleksandrovich ; Denisjuk Tatjana Alekseevna ; Grigorenko Aleksandr Petrovich ; Sarojan Karen Vanushovich ; Pokrovskij Mikhail Vladimirovich ; Krolevets Aleksandr Aleksandrovich ; Sitnik Mikhail Vladimirovich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2605847C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2016</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MANUFACTURE OR TREATMENT THEREOF</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS</topic><topic>NANOTECHNOLOGY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>Avtina Valentina Valerevna</creatorcontrib><creatorcontrib>Losenok Polina Igorevna</creatorcontrib><creatorcontrib>Bogachev Ilja Aleksandrovich</creatorcontrib><creatorcontrib>Denisjuk Tatjana Alekseevna</creatorcontrib><creatorcontrib>Grigorenko Aleksandr Petrovich</creatorcontrib><creatorcontrib>Sarojan Karen Vanushovich</creatorcontrib><creatorcontrib>Pokrovskij Mikhail Vladimirovich</creatorcontrib><creatorcontrib>Krolevets Aleksandr Aleksandrovich</creatorcontrib><creatorcontrib>Sitnik Mikhail Vladimirovich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Avtina Valentina Valerevna</au><au>Losenok Polina Igorevna</au><au>Bogachev Ilja Aleksandrovich</au><au>Denisjuk Tatjana Alekseevna</au><au>Grigorenko Aleksandr Petrovich</au><au>Sarojan Karen Vanushovich</au><au>Pokrovskij Mikhail Vladimirovich</au><au>Krolevets Aleksandr Aleksandrovich</au><au>Sitnik Mikhail Vladimirovich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><date>2016-12-27</date><risdate>2016</risdate><abstract>FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; rus
recordid cdi_epo_espacenet_RU2605847C2
source esp@cenet
subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT THEREOF
MEDICAL OR VETERINARY SCIENCE
NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS
NANOTECHNOLOGY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR RELEVANT APPARATUS
TRANSPORTING
title METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T19%3A31%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Avtina%20Valentina%20Valerevna&rft.date=2016-12-27&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2605847C2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true