METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM
FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:...
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| creator | Avtina Valentina Valerevna Losenok Polina Igorevna Bogachev Ilja Aleksandrovich Denisjuk Tatjana Alekseevna Grigorenko Aleksandr Petrovich Sarojan Karen Vanushovich Pokrovskij Mikhail Vladimirovich Krolevets Aleksandr Aleksandrovich Sitnik Mikhail Vladimirovich |
| description | FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex
Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр. |
| format | Patent |
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Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.</description><language>eng ; rus</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MANUFACTURE OR TREATMENT THEREOF ; MEDICAL OR VETERINARY SCIENCE ; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS ; NANOTECHNOLOGY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161227&DB=EPODOC&CC=RU&NR=2605847C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161227&DB=EPODOC&CC=RU&NR=2605847C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Avtina Valentina Valerevna</creatorcontrib><creatorcontrib>Losenok Polina Igorevna</creatorcontrib><creatorcontrib>Bogachev Ilja Aleksandrovich</creatorcontrib><creatorcontrib>Denisjuk Tatjana Alekseevna</creatorcontrib><creatorcontrib>Grigorenko Aleksandr Petrovich</creatorcontrib><creatorcontrib>Sarojan Karen Vanushovich</creatorcontrib><creatorcontrib>Pokrovskij Mikhail Vladimirovich</creatorcontrib><creatorcontrib>Krolevets Aleksandr Aleksandrovich</creatorcontrib><creatorcontrib>Sitnik Mikhail Vladimirovich</creatorcontrib><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><description>FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex
Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MANUFACTURE OR TREATMENT THEREOF</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS</subject><subject>NANOTECHNOLOGY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDzdQ3x8HdR8HdTCAjydwl19vRzV_Bz9PN3dgwIDvVxDQbJBPkHh4Y5Boc4hnj6KQCRt7-fl6OzgnuoLw8Da1piTnEqL5TmZlBwcw1x9tBNLciPTy0uSExOzUstiQ8KNTIzMLUwMXc2MiZCCQAZSioC</recordid><startdate>20161227</startdate><enddate>20161227</enddate><creator>Avtina Valentina Valerevna</creator><creator>Losenok Polina Igorevna</creator><creator>Bogachev Ilja Aleksandrovich</creator><creator>Denisjuk Tatjana Alekseevna</creator><creator>Grigorenko Aleksandr Petrovich</creator><creator>Sarojan Karen Vanushovich</creator><creator>Pokrovskij Mikhail Vladimirovich</creator><creator>Krolevets Aleksandr Aleksandrovich</creator><creator>Sitnik Mikhail Vladimirovich</creator><scope>EVB</scope></search><sort><creationdate>20161227</creationdate><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><author>Avtina Valentina Valerevna ; Losenok Polina Igorevna ; Bogachev Ilja Aleksandrovich ; Denisjuk Tatjana Alekseevna ; Grigorenko Aleksandr Petrovich ; Sarojan Karen Vanushovich ; Pokrovskij Mikhail Vladimirovich ; Krolevets Aleksandr Aleksandrovich ; Sitnik Mikhail Vladimirovich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2605847C23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2016</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MANUFACTURE OR TREATMENT THEREOF</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS</topic><topic>NANOTECHNOLOGY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>Avtina Valentina Valerevna</creatorcontrib><creatorcontrib>Losenok Polina Igorevna</creatorcontrib><creatorcontrib>Bogachev Ilja Aleksandrovich</creatorcontrib><creatorcontrib>Denisjuk Tatjana Alekseevna</creatorcontrib><creatorcontrib>Grigorenko Aleksandr Petrovich</creatorcontrib><creatorcontrib>Sarojan Karen Vanushovich</creatorcontrib><creatorcontrib>Pokrovskij Mikhail Vladimirovich</creatorcontrib><creatorcontrib>Krolevets Aleksandr Aleksandrovich</creatorcontrib><creatorcontrib>Sitnik Mikhail Vladimirovich</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Avtina Valentina Valerevna</au><au>Losenok Polina Igorevna</au><au>Bogachev Ilja Aleksandrovich</au><au>Denisjuk Tatjana Alekseevna</au><au>Grigorenko Aleksandr Petrovich</au><au>Sarojan Karen Vanushovich</au><au>Pokrovskij Mikhail Vladimirovich</au><au>Krolevets Aleksandr Aleksandrovich</au><au>Sitnik Mikhail Vladimirovich</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM</title><date>2016-12-27</date><risdate>2016</risdate><abstract>FIELD: chemistry.SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of konjac gum in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then benzene is added, obtained suspension is filtered and dried at room temperature.EFFECT: invention provides a simpler and faster process of producing nanocapsules, reducing accompanying loss at nanocapsules production (higher weight yield).1 cl, 1 dwg, 3 ex
Изобретение относится к способу получения нанокапсул розувастатина, характеризующемуся тем, что розувастатин медленно добавляют в суспензию конжаковой камеди в гексане, в присутствии 0,005 г препарата Е472с при перемешивании 1000 об/мин, при массовом соотношении оболочка:ядро 3:1 или 1:5, затем приливают бензол, полученную суспензию отфильтровывают и сушат при комнатной температуре. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул, уменьшение потерь при получении нанокапсул (увеличение выхода по массе). 1 ил., 3 пр.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT THEREOF MEDICAL OR VETERINARY SCIENCE NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS NANOTECHNOLOGY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING |
| title | METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN KONJAC GUM |
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