APTAMER FOR CHYMASE, AND ITS USE

FIELD: bioengineering.SUBSTANCE: aptamer connecting with chymase and inhibiting chymase activity is suggested, it contains nucleotide sequence expressed as XGAUAGANNUAAX, where Xand Xidentical or not identical to each other, and each means A or G, and Nand Nare identical or non identical to each oth...

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Hauptverfasser: TSZIN LIN, JAMAZAKI SATOKO, NAKAMURA JOSIKAZU, MURAGUTI MASAKHIRO, IKEDA KHISAKO
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JAMAZAKI SATOKO
NAKAMURA JOSIKAZU
MURAGUTI MASAKHIRO
IKEDA KHISAKO
description FIELD: bioengineering.SUBSTANCE: aptamer connecting with chymase and inhibiting chymase activity is suggested, it contains nucleotide sequence expressed as XGAUAGANNUAAX, where Xand Xidentical or not identical to each other, and each means A or G, and Nand Nare identical or non identical to each other, and each means A, G, C, U or T; complex including aptamer and functional substance, for example, substance with affinity, substance for marking, ferment, mean of the pharmaceutical delivery, pharmaceutical; pharmaceutical or reagent containing aptamer or complex; methods of detection and cleaning of the chymase using aptamer or complex.EFFECT: improved properties.16 cl, 8 dwg, 9 tbl, 9 ex Группа изобретений относится к обоасти биохимии и биотехнологии. Представлены аптамер, связывающийся с химазой и ингибирующий активность химазы, содержащий нуклеотидную последовательность, представленную как XGAUAGANNUAAX, где Xи Xидентичны или не идентичны друг другу и каждый означает A или G, а Nи Nидентичны или не идентичны друг другу и каждый означает A, G, C, U или T; комплекс, включающий аптамер и функциональное вещество, например вещество, обладающее сродством, вещество для мечения, фермент, средство доставки лекарственного средства, лекарственное средство; лекарственное средство или реагент, содержащее аптамер или комплекс; способы детекции и очистки химазы с использованием аптамера или комплекса. 9 н. и 7 з.п. ф-лы, 8 ил., 9 табл., 9 пр.
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complex including aptamer and functional substance, for example, substance with affinity, substance for marking, ferment, mean of the pharmaceutical delivery, pharmaceutical; pharmaceutical or reagent containing aptamer or complex; methods of detection and cleaning of the chymase using aptamer or complex.EFFECT: improved properties.16 cl, 8 dwg, 9 tbl, 9 ex Группа изобретений относится к обоасти биохимии и биотехнологии. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title APTAMER FOR CHYMASE, AND ITS USE
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