HIGHLY EFFECTIVE DOUBLE-STRANDED OLIGO-RNA STRUCTURE SUCH NANOPARTICLES AND METHOD OF ITS MANUFACTURING
FIELD: biotechnology.SUBSTANCE: group of inventions is described, including double-stranded oligo-RNA structure for efficient delivery of RNA, and a method of its manufacturing, a nanoparticle containing the above-mentioned double-stranded oligo-RNA structure, a method of controlling the gene expres...
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| creator | KIM KHAN-NA KHAN BORAM PAK KHAN O CHKHE CHEJUK |
| description | FIELD: biotechnology.SUBSTANCE: group of inventions is described, including double-stranded oligo-RNA structure for efficient delivery of RNA, and a method of its manufacturing, a nanoparticle containing the above-mentioned double-stranded oligo-RNA structure, a method of controlling the gene expression in vitro by use of the above-mentioned oligo-RNA structure, and a method of controlling the gene expression in vivo by use of the above-mentioned nanoparticle.EFFECT: invention expands the range of means of delivery of RNA to the cells of the body.28 cl, 5 dwg, 1 tbl, 4 ex
Изобретения относятся к области биохимии. Описана группа изобретений, включающая двухцепочечную олиго-РНК конструкцию для эффективной доставки РНК и способ ее изготовления, наночастицу, содержащую вышеуказанную двухцепочечную олиго-РНК конструкцию, способ регулирования экспрессии генапутем использования вышеуказанной олиго-РНК конструкции и способ регулирования экспрессии генапутем использования вышеуказанной наночастицы. Изобретение расширяет арсенал средств доставки РНК в клетки организма. 8 н. и 20 з.п. ф-лы, 5 ил., 1 табл., 4 пр. |
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Изобретения относятся к области биохимии. Описана группа изобретений, включающая двухцепочечную олиго-РНК конструкцию для эффективной доставки РНК и способ ее изготовления, наночастицу, содержащую вышеуказанную двухцепочечную олиго-РНК конструкцию, способ регулирования экспрессии генапутем использования вышеуказанной олиго-РНК конструкции и способ регулирования экспрессии генапутем использования вышеуказанной наночастицы. Изобретение расширяет арсенал средств доставки РНК в клетки организма. 8 н. и 20 з.п. ф-лы, 5 ил., 1 табл., 4 пр.</description><language>eng ; rus</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160310&DB=EPODOC&CC=RU&NR=2577227C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160310&DB=EPODOC&CC=RU&NR=2577227C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM KHAN-NA</creatorcontrib><creatorcontrib>KHAN BORAM</creatorcontrib><creatorcontrib>PAK KHAN O</creatorcontrib><creatorcontrib>CHKHE CHEJUK</creatorcontrib><title>HIGHLY EFFECTIVE DOUBLE-STRANDED OLIGO-RNA STRUCTURE SUCH NANOPARTICLES AND METHOD OF ITS MANUFACTURING</title><description>FIELD: biotechnology.SUBSTANCE: group of inventions is described, including double-stranded oligo-RNA structure for efficient delivery of RNA, and a method of its manufacturing, a nanoparticle containing the above-mentioned double-stranded oligo-RNA structure, a method of controlling the gene expression in vitro by use of the above-mentioned oligo-RNA structure, and a method of controlling the gene expression in vivo by use of the above-mentioned nanoparticle.EFFECT: invention expands the range of means of delivery of RNA to the cells of the body.28 cl, 5 dwg, 1 tbl, 4 ex
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Изобретения относятся к области биохимии. Описана группа изобретений, включающая двухцепочечную олиго-РНК конструкцию для эффективной доставки РНК и способ ее изготовления, наночастицу, содержащую вышеуказанную двухцепочечную олиго-РНК конструкцию, способ регулирования экспрессии генапутем использования вышеуказанной олиго-РНК конструкции и способ регулирования экспрессии генапутем использования вышеуказанной наночастицы. Изобретение расширяет арсенал средств доставки РНК в клетки организма. 8 н. и 20 з.п. ф-лы, 5 ил., 1 табл., 4 пр.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | HIGHLY EFFECTIVE DOUBLE-STRANDED OLIGO-RNA STRUCTURE SUCH NANOPARTICLES AND METHOD OF ITS MANUFACTURING |
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