METHOD OF OBTAINING NANOCAPSULES OF ANTIBIOTICS

FIELD: medicine.SUBSTANCE: xanthan gum is used as nanocapsule shell, antibiotic is used as core. Weight ratio core: shell constitutes 1:3. In accordance with method by invention antibiotic powder is added into suspension of xanthan gum in hexane, containing E472c preparation as surface-active substa...

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Hauptverfasser:	KROLEVETS ALEKSANDR ALEKSANDROVICH, BOGACHEV IL'JA ALEKSANDROVICH, MEDVEDEVA JANA VLADIMIROVNA, BOJKO EKATERINA EVGEN'EVNA, NIKITIN KIRILL SERGEEVICH
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Sprache:	eng ; rus
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT THEREOF MEDICAL OR VETERINARY SCIENCE NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS NANOTECHNOLOGY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING
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creator	KROLEVETS ALEKSANDR ALEKSANDROVICH BOGACHEV IL'JA ALEKSANDROVICH MEDVEDEVA JANA VLADIMIROVNA BOJKO EKATERINA EVGEN'EVNA NIKITIN KIRILL SERGEEVICH
description	FIELD: medicine.SUBSTANCE: xanthan gum is used as nanocapsule shell, antibiotic is used as core. Weight ratio core: shell constitutes 1:3. In accordance with method by invention antibiotic powder is added into suspension of xanthan gum in hexane, containing E472c preparation as surface-active substance. After that, methylene chloride is added. Obtained suspension of nanocapsules is filtered and dried. Process is realised at 25°C for 15 minutes.EFFECT: simplification and acceleration of process of obtaining nanocapsules and increase of output by weight.5 dwg, 12 ex Изобретение относится к способу получения нанокапсул антибиотиков. В качестве оболочки нанокапсул используется ксантановая камедь, в качестве ядра - антибиотик. Массовое соотношение ядро:оболочка составляет 1:3. Согласно способу по изобретению порошок антибиотика добавляют в суспензию ксантановой камеди в гексане, содержащую препарат Е472с в качестве поверхностно-активного вещества. Затем добавляют хлористый метилен. Полученную суспензию нанокапсул отфильтровывают и сушат. Процесс осуществляют при 25°C в течение 15 минут. Способ обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 5 ил., 12 пр.
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Weight ratio core: shell constitutes 1:3. In accordance with method by invention antibiotic powder is added into suspension of xanthan gum in hexane, containing E472c preparation as surface-active substance. After that, methylene chloride is added. Obtained suspension of nanocapsules is filtered and dried. Process is realised at 25°C for 15 minutes.EFFECT: simplification and acceleration of process of obtaining nanocapsules and increase of output by weight.5 dwg, 12 ex Изобретение относится к способу получения нанокапсул антибиотиков. В качестве оболочки нанокапсул используется ксантановая камедь, в качестве ядра - антибиотик. Массовое соотношение ядро:оболочка составляет 1:3. Согласно способу по изобретению порошок антибиотика добавляют в суспензию ксантановой камеди в гексане, содержащую препарат Е472с в качестве поверхностно-активного вещества. Затем добавляют хлористый метилен. Полученную суспензию нанокапсул отфильтровывают и сушат. Процесс осуществляют при 25°C в течение 15 минут. Способ обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 5 ил., 12 пр.</description><language>eng ; rus</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MANUFACTURE OR TREATMENT THEREOF ; MEDICAL OR VETERINARY SCIENCE ; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS ; NANOTECHNOLOGY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151010&DB=EPODOC&CC=RU&NR=2564898C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151010&DB=EPODOC&CC=RU&NR=2564898C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KROLEVETS ALEKSANDR ALEKSANDROVICH</creatorcontrib><creatorcontrib>BOGACHEV IL'JA ALEKSANDROVICH</creatorcontrib><creatorcontrib>MEDVEDEVA JANA VLADIMIROVNA</creatorcontrib><creatorcontrib>BOJKO EKATERINA EVGEN'EVNA</creatorcontrib><creatorcontrib>NIKITIN KIRILL SERGEEVICH</creatorcontrib><title>METHOD OF OBTAINING NANOCAPSULES OF ANTIBIOTICS</title><description>FIELD: medicine.SUBSTANCE: xanthan gum is used as nanocapsule shell, antibiotic is used as core. Weight ratio core: shell constitutes 1:3. In accordance with method by invention antibiotic powder is added into suspension of xanthan gum in hexane, containing E472c preparation as surface-active substance. After that, methylene chloride is added. Obtained suspension of nanocapsules is filtered and dried. Process is realised at 25°C for 15 minutes.EFFECT: simplification and acceleration of process of obtaining nanocapsules and increase of output by weight.5 dwg, 12 ex Изобретение относится к способу получения нанокапсул антибиотиков. В качестве оболочки нанокапсул используется ксантановая камедь, в качестве ядра - антибиотик. Массовое соотношение ядро:оболочка составляет 1:3. Согласно способу по изобретению порошок антибиотика добавляют в суспензию ксантановой камеди в гексане, содержащую препарат Е472с в качестве поверхностно-активного вещества. Затем добавляют хлористый метилен. Полученную суспензию нанокапсул отфильтровывают и сушат. Процесс осуществляют при 25°C в течение 15 минут. 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Weight ratio core: shell constitutes 1:3. In accordance with method by invention antibiotic powder is added into suspension of xanthan gum in hexane, containing E472c preparation as surface-active substance. After that, methylene chloride is added. Obtained suspension of nanocapsules is filtered and dried. Process is realised at 25°C for 15 minutes.EFFECT: simplification and acceleration of process of obtaining nanocapsules and increase of output by weight.5 dwg, 12 ex Изобретение относится к способу получения нанокапсул антибиотиков. В качестве оболочки нанокапсул используется ксантановая камедь, в качестве ядра - антибиотик. Массовое соотношение ядро:оболочка составляет 1:3. Согласно способу по изобретению порошок антибиотика добавляют в суспензию ксантановой камеди в гексане, содержащую препарат Е472с в качестве поверхностно-активного вещества. Затем добавляют хлористый метилен. Полученную суспензию нанокапсул отфильтровывают и сушат. Процесс осуществляют при 25°C в течение 15 минут. Способ обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 5 ил., 12 пр.</abstract><oa>free_for_read</oa></addata></record>
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subjects	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT THEREOF MEDICAL OR VETERINARY SCIENCE NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS NANOTECHNOLOGY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING
title	METHOD OF OBTAINING NANOCAPSULES OF ANTIBIOTICS
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