METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR

FIELD: nanotechnology.SUBSTANCE: invention describes a method of production of antibiotic nanocapsules by the method of precipitation with nonsolvent, in which into the suspension of 1.5 g of agar-agar, used as a shell of the nanocapsules, in hexane and 0.01 g E472s as a surfactant, 0.5 g of the ant...

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Hauptverfasser: KROLEVETS ALEKSANDR ALEKSANDROVICH, BOGACHEV IL'JA ALEKSANDROVICH, MEDVEDEVA JANA VLADIMIROVNA, BOJKO EKATERINA EVGEN'EVNA, NIKITIN KIRILL SERGEEVICH
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creator KROLEVETS ALEKSANDR ALEKSANDROVICH
BOGACHEV IL'JA ALEKSANDROVICH
MEDVEDEVA JANA VLADIMIROVNA
BOJKO EKATERINA EVGEN'EVNA
NIKITIN KIRILL SERGEEVICH
description FIELD: nanotechnology.SUBSTANCE: invention describes a method of production of antibiotic nanocapsules by the method of precipitation with nonsolvent, in which into the suspension of 1.5 g of agar-agar, used as a shell of the nanocapsules, in hexane and 0.01 g E472s as a surfactant, 0.5 g of the antibiotic powder is added in small portions, then 5 ml of acetonitrile as the precipitant is added dropwise, then the resulting suspension of nanocapsules is filtered and dried.EFFECT: simplification and acceleration of the process of producing the nanocapsules, and increase in the yield by weight.11 ex Изобретение относится в области нанотехнологии, медицины и фармакологии и описывает способ получения нанокапсул антибиотиков методом осаждения нерастворителем, в котором в суспензию 1,5 г агар-агара, использующегося в качестве оболочки нанокапсул, в гексане и 0,01 г Е472с в качестве поверхностно-активного вещества небольшими порциями добавляют 0,5 г порошка антибиотика, затем по каплям добавляют 5 мл ацетонитрила в качестве осадителя, затем полученную суспензию нанокапсул отфильтровывают и сушат. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 11 пр.
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Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 11 пр.</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT THEREOF
MEDICAL OR VETERINARY SCIENCE
NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS
NANOTECHNOLOGY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR RELEVANT APPARATUS
TRANSPORTING
title METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR
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