METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR
FIELD: nanotechnology.SUBSTANCE: invention describes a method of production of antibiotic nanocapsules by the method of precipitation with nonsolvent, in which into the suspension of 1.5 g of agar-agar, used as a shell of the nanocapsules, in hexane and 0.01 g E472s as a surfactant, 0.5 g of the ant...
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creator | KROLEVETS ALEKSANDR ALEKSANDROVICH BOGACHEV IL'JA ALEKSANDROVICH MEDVEDEVA JANA VLADIMIROVNA BOJKO EKATERINA EVGEN'EVNA NIKITIN KIRILL SERGEEVICH |
description | FIELD: nanotechnology.SUBSTANCE: invention describes a method of production of antibiotic nanocapsules by the method of precipitation with nonsolvent, in which into the suspension of 1.5 g of agar-agar, used as a shell of the nanocapsules, in hexane and 0.01 g E472s as a surfactant, 0.5 g of the antibiotic powder is added in small portions, then 5 ml of acetonitrile as the precipitant is added dropwise, then the resulting suspension of nanocapsules is filtered and dried.EFFECT: simplification and acceleration of the process of producing the nanocapsules, and increase in the yield by weight.11 ex
Изобретение относится в области нанотехнологии, медицины и фармакологии и описывает способ получения нанокапсул антибиотиков методом осаждения нерастворителем, в котором в суспензию 1,5 г агар-агара, использующегося в качестве оболочки нанокапсул, в гексане и 0,01 г Е472с в качестве поверхностно-активного вещества небольшими порциями добавляют 0,5 г порошка антибиотика, затем по каплям добавляют 5 мл ацетонитрила в качестве осадителя, затем полученную суспензию нанокапсул отфильтровывают и сушат. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 11 пр. |
format | Patent |
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Изобретение относится в области нанотехнологии, медицины и фармакологии и описывает способ получения нанокапсул антибиотиков методом осаждения нерастворителем, в котором в суспензию 1,5 г агар-агара, использующегося в качестве оболочки нанокапсул, в гексане и 0,01 г Е472с в качестве поверхностно-активного вещества небольшими порциями добавляют 0,5 г порошка антибиотика, затем по каплям добавляют 5 мл ацетонитрила в качестве осадителя, затем полученную суспензию нанокапсул отфильтровывают и сушат. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 11 пр.</description><language>eng ; rus</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MANUFACTURE OR TREATMENT THEREOF ; MEDICAL OR VETERINARY SCIENCE ; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS ; NANOTECHNOLOGY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150820&DB=EPODOC&CC=RU&NR=2560663C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150820&DB=EPODOC&CC=RU&NR=2560663C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KROLEVETS ALEKSANDR ALEKSANDROVICH</creatorcontrib><creatorcontrib>BOGACHEV IL'JA ALEKSANDROVICH</creatorcontrib><creatorcontrib>MEDVEDEVA JANA VLADIMIROVNA</creatorcontrib><creatorcontrib>BOJKO EKATERINA EVGEN'EVNA</creatorcontrib><creatorcontrib>NIKITIN KIRILL SERGEEVICH</creatorcontrib><title>METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR</title><description>FIELD: nanotechnology.SUBSTANCE: invention describes a method of production of antibiotic nanocapsules by the method of precipitation with nonsolvent, in which into the suspension of 1.5 g of agar-agar, used as a shell of the nanocapsules, in hexane and 0.01 g E472s as a surfactant, 0.5 g of the antibiotic powder is added in small portions, then 5 ml of acetonitrile as the precipitant is added dropwise, then the resulting suspension of nanocapsules is filtered and dried.EFFECT: simplification and acceleration of the process of producing the nanocapsules, and increase in the yield by weight.11 ex
Изобретение относится в области нанотехнологии, медицины и фармакологии и описывает способ получения нанокапсул антибиотиков методом осаждения нерастворителем, в котором в суспензию 1,5 г агар-агара, использующегося в качестве оболочки нанокапсул, в гексане и 0,01 г Е472с в качестве поверхностно-активного вещества небольшими порциями добавляют 0,5 г порошка антибиотика, затем по каплям добавляют 5 мл ацетонитрила в качестве осадителя, затем полученную суспензию нанокапсул отфильтровывают и сушат. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 11 пр.</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MANUFACTURE OR TREATMENT THEREOF</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS</subject><subject>NANOTECHNOLOGY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDxdQ3x8HdR8HdTCAjydwl1DvH09wPxHP1CPJ08_UM8nRX8HP38nR0DgkN9XIMVPP0UHN0dg3RBBA8Da1piTnEqL5TmZlBwcw1x9tBNLciPTy0uSExOzUstiQ8KNTI1MzAzM3Y2NCZCCQCq0Ckp</recordid><startdate>20150820</startdate><enddate>20150820</enddate><creator>KROLEVETS ALEKSANDR ALEKSANDROVICH</creator><creator>BOGACHEV IL'JA ALEKSANDROVICH</creator><creator>MEDVEDEVA JANA VLADIMIROVNA</creator><creator>BOJKO EKATERINA EVGEN'EVNA</creator><creator>NIKITIN KIRILL SERGEEVICH</creator><scope>EVB</scope></search><sort><creationdate>20150820</creationdate><title>METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR</title><author>KROLEVETS ALEKSANDR ALEKSANDROVICH ; BOGACHEV IL'JA ALEKSANDROVICH ; MEDVEDEVA JANA VLADIMIROVNA ; BOJKO EKATERINA EVGEN'EVNA ; NIKITIN KIRILL SERGEEVICH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2560663C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2015</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MANUFACTURE OR TREATMENT THEREOF</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS</topic><topic>NANOTECHNOLOGY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>KROLEVETS ALEKSANDR ALEKSANDROVICH</creatorcontrib><creatorcontrib>BOGACHEV IL'JA ALEKSANDROVICH</creatorcontrib><creatorcontrib>MEDVEDEVA JANA VLADIMIROVNA</creatorcontrib><creatorcontrib>BOJKO EKATERINA EVGEN'EVNA</creatorcontrib><creatorcontrib>NIKITIN KIRILL SERGEEVICH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KROLEVETS ALEKSANDR ALEKSANDROVICH</au><au>BOGACHEV IL'JA ALEKSANDROVICH</au><au>MEDVEDEVA JANA VLADIMIROVNA</au><au>BOJKO EKATERINA EVGEN'EVNA</au><au>NIKITIN KIRILL SERGEEVICH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR</title><date>2015-08-20</date><risdate>2015</risdate><abstract>FIELD: nanotechnology.SUBSTANCE: invention describes a method of production of antibiotic nanocapsules by the method of precipitation with nonsolvent, in which into the suspension of 1.5 g of agar-agar, used as a shell of the nanocapsules, in hexane and 0.01 g E472s as a surfactant, 0.5 g of the antibiotic powder is added in small portions, then 5 ml of acetonitrile as the precipitant is added dropwise, then the resulting suspension of nanocapsules is filtered and dried.EFFECT: simplification and acceleration of the process of producing the nanocapsules, and increase in the yield by weight.11 ex
Изобретение относится в области нанотехнологии, медицины и фармакологии и описывает способ получения нанокапсул антибиотиков методом осаждения нерастворителем, в котором в суспензию 1,5 г агар-агара, использующегося в качестве оболочки нанокапсул, в гексане и 0,01 г Е472с в качестве поверхностно-активного вещества небольшими порциями добавляют 0,5 г порошка антибиотика, затем по каплям добавляют 5 мл ацетонитрила в качестве осадителя, затем полученную суспензию нанокапсул отфильтровывают и сушат. Изобретение обеспечивает упрощение и ускорение процесса получения нанокапсул и увеличение выхода по массе. 11 пр.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT THEREOF MEDICAL OR VETERINARY SCIENCE NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS NANOTECHNOLOGY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING |
title | METHOD OF PRODUCTION OF ANTIBIOTIC NANOCAPSULES IN AGAR-AGAR |
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