METHOD FOR PRODUCING 2-METHYLENE-1,3-DINITROXYPROPANE AND USING 2-METHYLENE-1,3-DINITROXYPROPANE AS ANTI-ISCHEMIC AGENT
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a method for producing 2-methylene-1,3-dinitroxypropane. The method involves a reaction of silver nitrate and tris(chloromethyl)acetic acid in the acetonitrile medium. The reaction is performed at heating to 60-70°C.EFFECT: method enables...
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| creator | MITROKHIN NIKOLAJ MIKHAJLOVICH KOREPIN ANATOLIJ GEORGIEVICH VESELOV SERGEJ VLADIMIROVICH GLUSHAKOVA NATAL'JA MIKHAJLOVNA |
| description | FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a method for producing 2-methylene-1,3-dinitroxypropane. The method involves a reaction of silver nitrate and tris(chloromethyl)acetic acid in the acetonitrile medium. The reaction is performed at heating to 60-70°C.EFFECT: method enables producing the good yield product from the accessible compound in the comfortable medium as well as reducing the number of stages.5 dwg, 5 tbl
Изобретение относится к способу получения 2-метилен-1,3-динитроксипропана. Способ включает действие нитрата серебра на трис(хлорметил)уксусную кислоту в среде ацетонитрила. При этом реакцию проводят при нагревании до 60-70°С. Способ позволяет получать продукт с удовлетворительным выходом из доступного соединения в мягких условиях, а также сократить количество стадий. 5 ил., 5 табл. |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD FOR PRODUCING 2-METHYLENE-1,3-DINITROXYPROPANE AND USING 2-METHYLENE-1,3-DINITROXYPROPANE AS ANTI-ISCHEMIC AGENT |
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