METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS
FIELD: medicine.SUBSTANCE: viral hepatitis in simulated in laboratory animals (rats) with D-galactosamine. Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: m...
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creator | CHURIN ALEKSEJ ALEKSANDROVICH ARTAMONOV ANDREJ VLADIMIROVICH BEKAREV ANDREJ ALEKSANDROVICH DYGAJ ALEKSANDR MIKHAJLOVICH MIROSHNICHENKO LARISA ARKAD'EVNA CHAJKOVSKIJ ALEKSANDR VASIL'EVICH MADONOV PAVEL GENNAD'EVICH ZJUZ'KOV GLEB NIKOLAEVICH ZHDANOV VADIM VADIMOVICH UDUT ELENA VLADIMIROVNA SIMANINA ELENA VLADISLAVNA |
description | FIELD: medicine.SUBSTANCE: viral hepatitis in simulated in laboratory animals (rats) with D-galactosamine. Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: method enables reducing a severity of metabolic and morphological hepatic disorders effectively in stimulating hepatitis identical to viral hepatitis in a human with underlying reduced xenobiotic load on the body.1 ex, 3 tbl
Изобретение относится к медицине, в частности к фармакологии и гепатологии, и касается терапии гепатитов, изучаемой в эксперименте. Для этого у лабораторных животных (крыс) моделируют вирусный гепатит с помощью D-галактозамина. Лечение гепатита проводят путем однократного перорального введения иммобилизированной гиалуронидазы в дозе 25 ЕД/кг. Введение осуществляют перед моделированием, либо одновременно с началом моделирования. Способ позволяет эффективно снижать тяжесть метаболических и морфологических нарушений печени при моделировании гепатита, идентичного вирусному гепатиту у человека, на фоне снижения ксенобиотической нагрузки на организм. 1 пр., 3 табл. |
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Изобретение относится к медицине, в частности к фармакологии и гепатологии, и касается терапии гепатитов, изучаемой в эксперименте. Для этого у лабораторных животных (крыс) моделируют вирусный гепатит с помощью D-галактозамина. Лечение гепатита проводят путем однократного перорального введения иммобилизированной гиалуронидазы в дозе 25 ЕД/кг. Введение осуществляют перед моделированием, либо одновременно с началом моделирования. Способ позволяет эффективно снижать тяжесть метаболических и морфологических нарушений печени при моделировании гепатита, идентичного вирусному гепатиту у человека, на фоне снижения ксенобиотической нагрузки на организм. 1 пр., 3 табл.</description><language>eng ; rus</language><subject>ADVERTISING ; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE ; CRYPTOGRAPHY ; DIAGRAMS ; DISPLAY ; EDUCATION ; EDUCATIONAL OR DEMONSTRATION APPLIANCES ; GLOBES ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PHYSICS ; PLANETARIA ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SEALS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140720&DB=EPODOC&CC=RU&NR=2522942C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140720&DB=EPODOC&CC=RU&NR=2522942C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHURIN ALEKSEJ ALEKSANDROVICH</creatorcontrib><creatorcontrib>ARTAMONOV ANDREJ VLADIMIROVICH</creatorcontrib><creatorcontrib>BEKAREV ANDREJ ALEKSANDROVICH</creatorcontrib><creatorcontrib>DYGAJ ALEKSANDR MIKHAJLOVICH</creatorcontrib><creatorcontrib>MIROSHNICHENKO LARISA ARKAD'EVNA</creatorcontrib><creatorcontrib>CHAJKOVSKIJ ALEKSANDR VASIL'EVICH</creatorcontrib><creatorcontrib>MADONOV PAVEL GENNAD'EVICH</creatorcontrib><creatorcontrib>ZJUZ'KOV GLEB NIKOLAEVICH</creatorcontrib><creatorcontrib>ZHDANOV VADIM VADIMOVICH</creatorcontrib><creatorcontrib>UDUT ELENA VLADIMIROVNA</creatorcontrib><creatorcontrib>SIMANINA ELENA VLADISLAVNA</creatorcontrib><title>METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS</title><description>FIELD: medicine.SUBSTANCE: viral hepatitis in simulated in laboratory animals (rats) with D-galactosamine. Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: method enables reducing a severity of metabolic and morphological hepatic disorders effectively in stimulating hepatitis identical to viral hepatitis in a human with underlying reduced xenobiotic load on the body.1 ex, 3 tbl
Изобретение относится к медицине, в частности к фармакологии и гепатологии, и касается терапии гепатитов, изучаемой в эксперименте. Для этого у лабораторных животных (крыс) моделируют вирусный гепатит с помощью D-галактозамина. Лечение гепатита проводят путем однократного перорального введения иммобилизированной гиалуронидазы в дозе 25 ЕД/кг. Введение осуществляют перед моделированием, либо одновременно с началом моделирования. Способ позволяет эффективно снижать тяжесть метаболических и морфологических нарушений печени при моделировании гепатита, идентичного вирусному гепатиту у человека, на фоне снижения ксенобиотической нагрузки на организм. 1 пр., 3 табл.</description><subject>ADVERTISING</subject><subject>APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE</subject><subject>CRYPTOGRAPHY</subject><subject>DIAGRAMS</subject><subject>DISPLAY</subject><subject>EDUCATION</subject><subject>EDUCATIONAL OR DEMONSTRATION APPLIANCES</subject><subject>GLOBES</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PHYSICS</subject><subject>PLANETARIA</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SEALS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDxdQ3x8HdRcPMPUnCNCHAN8vR19Qtx9FEI8XANcgyIVPB3U_BwDXAM8QzxDOZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfFBoUamRkaWJkbOhsZEKAEAYBwlCg</recordid><startdate>20140720</startdate><enddate>20140720</enddate><creator>CHURIN ALEKSEJ ALEKSANDROVICH</creator><creator>ARTAMONOV ANDREJ VLADIMIROVICH</creator><creator>BEKAREV ANDREJ ALEKSANDROVICH</creator><creator>DYGAJ ALEKSANDR MIKHAJLOVICH</creator><creator>MIROSHNICHENKO LARISA ARKAD'EVNA</creator><creator>CHAJKOVSKIJ ALEKSANDR VASIL'EVICH</creator><creator>MADONOV PAVEL GENNAD'EVICH</creator><creator>ZJUZ'KOV GLEB NIKOLAEVICH</creator><creator>ZHDANOV VADIM VADIMOVICH</creator><creator>UDUT ELENA VLADIMIROVNA</creator><creator>SIMANINA ELENA VLADISLAVNA</creator><scope>EVB</scope></search><sort><creationdate>20140720</creationdate><title>METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS</title><author>CHURIN ALEKSEJ ALEKSANDROVICH ; ARTAMONOV ANDREJ VLADIMIROVICH ; BEKAREV ANDREJ ALEKSANDROVICH ; DYGAJ ALEKSANDR MIKHAJLOVICH ; MIROSHNICHENKO LARISA ARKAD'EVNA ; CHAJKOVSKIJ ALEKSANDR VASIL'EVICH ; MADONOV PAVEL GENNAD'EVICH ; ZJUZ'KOV GLEB NIKOLAEVICH ; ZHDANOV VADIM VADIMOVICH ; UDUT ELENA VLADIMIROVNA ; SIMANINA ELENA VLADISLAVNA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2522942C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2014</creationdate><topic>ADVERTISING</topic><topic>APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE</topic><topic>CRYPTOGRAPHY</topic><topic>DIAGRAMS</topic><topic>DISPLAY</topic><topic>EDUCATION</topic><topic>EDUCATIONAL OR DEMONSTRATION APPLIANCES</topic><topic>GLOBES</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PHYSICS</topic><topic>PLANETARIA</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SEALS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHURIN ALEKSEJ ALEKSANDROVICH</creatorcontrib><creatorcontrib>ARTAMONOV ANDREJ VLADIMIROVICH</creatorcontrib><creatorcontrib>BEKAREV ANDREJ ALEKSANDROVICH</creatorcontrib><creatorcontrib>DYGAJ ALEKSANDR MIKHAJLOVICH</creatorcontrib><creatorcontrib>MIROSHNICHENKO LARISA ARKAD'EVNA</creatorcontrib><creatorcontrib>CHAJKOVSKIJ ALEKSANDR VASIL'EVICH</creatorcontrib><creatorcontrib>MADONOV PAVEL GENNAD'EVICH</creatorcontrib><creatorcontrib>ZJUZ'KOV GLEB NIKOLAEVICH</creatorcontrib><creatorcontrib>ZHDANOV VADIM VADIMOVICH</creatorcontrib><creatorcontrib>UDUT ELENA VLADIMIROVNA</creatorcontrib><creatorcontrib>SIMANINA ELENA VLADISLAVNA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHURIN ALEKSEJ ALEKSANDROVICH</au><au>ARTAMONOV ANDREJ VLADIMIROVICH</au><au>BEKAREV ANDREJ ALEKSANDROVICH</au><au>DYGAJ ALEKSANDR MIKHAJLOVICH</au><au>MIROSHNICHENKO LARISA ARKAD'EVNA</au><au>CHAJKOVSKIJ ALEKSANDR VASIL'EVICH</au><au>MADONOV PAVEL GENNAD'EVICH</au><au>ZJUZ'KOV GLEB NIKOLAEVICH</au><au>ZHDANOV VADIM VADIMOVICH</au><au>UDUT ELENA VLADIMIROVNA</au><au>SIMANINA ELENA VLADISLAVNA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS</title><date>2014-07-20</date><risdate>2014</risdate><abstract>FIELD: medicine.SUBSTANCE: viral hepatitis in simulated in laboratory animals (rats) with D-galactosamine. Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: method enables reducing a severity of metabolic and morphological hepatic disorders effectively in stimulating hepatitis identical to viral hepatitis in a human with underlying reduced xenobiotic load on the body.1 ex, 3 tbl
Изобретение относится к медицине, в частности к фармакологии и гепатологии, и касается терапии гепатитов, изучаемой в эксперименте. Для этого у лабораторных животных (крыс) моделируют вирусный гепатит с помощью D-галактозамина. Лечение гепатита проводят путем однократного перорального введения иммобилизированной гиалуронидазы в дозе 25 ЕД/кг. Введение осуществляют перед моделированием, либо одновременно с началом моделирования. Способ позволяет эффективно снижать тяжесть метаболических и морфологических нарушений печени при моделировании гепатита, идентичного вирусному гепатиту у человека, на фоне снижения ксенобиотической нагрузки на организм. 1 пр., 3 табл.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ADVERTISING APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE CRYPTOGRAPHY DIAGRAMS DISPLAY EDUCATION EDUCATIONAL OR DEMONSTRATION APPLIANCES GLOBES HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PHYSICS PLANETARIA PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEALS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS |
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