METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS

FIELD: medicine.SUBSTANCE: viral hepatitis in simulated in laboratory animals (rats) with D-galactosamine. Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: m...

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Hauptverfasser: CHURIN ALEKSEJ ALEKSANDROVICH, ARTAMONOV ANDREJ VLADIMIROVICH, BEKAREV ANDREJ ALEKSANDROVICH, DYGAJ ALEKSANDR MIKHAJLOVICH, MIROSHNICHENKO LARISA ARKAD'EVNA, CHAJKOVSKIJ ALEKSANDR VASIL'EVICH, MADONOV PAVEL GENNAD'EVICH, ZJUZ'KOV GLEB NIKOLAEVICH, ZHDANOV VADIM VADIMOVICH, UDUT ELENA VLADIMIROVNA, SIMANINA ELENA VLADISLAVNA
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creator CHURIN ALEKSEJ ALEKSANDROVICH
ARTAMONOV ANDREJ VLADIMIROVICH
BEKAREV ANDREJ ALEKSANDROVICH
DYGAJ ALEKSANDR MIKHAJLOVICH
MIROSHNICHENKO LARISA ARKAD'EVNA
CHAJKOVSKIJ ALEKSANDR VASIL'EVICH
MADONOV PAVEL GENNAD'EVICH
ZJUZ'KOV GLEB NIKOLAEVICH
ZHDANOV VADIM VADIMOVICH
UDUT ELENA VLADIMIROVNA
SIMANINA ELENA VLADISLAVNA
description FIELD: medicine.SUBSTANCE: viral hepatitis in simulated in laboratory animals (rats) with D-galactosamine. Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: method enables reducing a severity of metabolic and morphological hepatic disorders effectively in stimulating hepatitis identical to viral hepatitis in a human with underlying reduced xenobiotic load on the body.1 ex, 3 tbl Изобретение относится к медицине, в частности к фармакологии и гепатологии, и касается терапии гепатитов, изучаемой в эксперименте. Для этого у лабораторных животных (крыс) моделируют вирусный гепатит с помощью D-галактозамина. Лечение гепатита проводят путем однократного перорального введения иммобилизированной гиалуронидазы в дозе 25 ЕД/кг. Введение осуществляют перед моделированием, либо одновременно с началом моделирования. Способ позволяет эффективно снижать тяжесть метаболических и морфологических нарушений печени при моделировании гепатита, идентичного вирусному гепатиту у человека, на фоне снижения ксенобиотической нагрузки на организм. 1 пр., 3 табл.
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Hepatitis is treated by single oral administration of immobilised hyaluronidase 25 unit/kg. Administration either precedes simulation, or is combined with the beginning of stimulation.EFFECT: method enables reducing a severity of metabolic and morphological hepatic disorders effectively in stimulating hepatitis identical to viral hepatitis in a human with underlying reduced xenobiotic load on the body.1 ex, 3 tbl Изобретение относится к медицине, в частности к фармакологии и гепатологии, и касается терапии гепатитов, изучаемой в эксперименте. Для этого у лабораторных животных (крыс) моделируют вирусный гепатит с помощью D-галактозамина. Лечение гепатита проводят путем однократного перорального введения иммобилизированной гиалуронидазы в дозе 25 ЕД/кг. Введение осуществляют перед моделированием, либо одновременно с началом моделирования. 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subjects ADVERTISING
APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE
CRYPTOGRAPHY
DIAGRAMS
DISPLAY
EDUCATION
EDUCATIONAL OR DEMONSTRATION APPLIANCES
GLOBES
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PLANETARIA
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SEALS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD FOR EXPERIMENTAL THERAPY OF HEPATITIS
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