METHOD FOR DERMAL FLAP SURVIVAL GROWTH IN REDUCED CIRCULATION WITH SILDENAFIL
FIELD: medicine.SUBSTANCE: dermal flap is simulated in laboratory animals on the second day of experiment. Sildenafil 2.2 mg/kg is introduced intraperitoneally on the first, third and fifth day of the experiment.EFFECT: dermal flap survival rate in reduced circulation with no side effects.1 tbl, 1 e...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; rus |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KOCHKAROV VLADIMIR ISKHAKOVICH GUDYREV OLEG SERGEEVICH EFREMENKOVA DAR'JA AFONAS'EVNA LAZARENKO VIKTOR ANATOL'EVICH ZHERNAKOVA NINA IVANOVNA ARUSTAMOVA ANNA ALEKSANDROVNA KOLESNIK INGA MIKHAJLOVNA DANILENKO LJUDMILA MIKHAJLOVNA MOLCHANOVA OL'GA VIKTOROVNA JAKUSHEV VLADIMIR VLADIMIROVICH POKROVSKIJ MIKHAIL VLADIMIROVICH DOLZHIKOV ALEKSANDR ANATOL'EVICH KHODOV SERGEJ VLADIMIROVICH ALEKHIN SERGEJ ALEKSANDROVICH GUREEV VLADIMIR VLADIMIROVICH DOLZHIKOVA IRINA NIKOLAEVNA POKROVSKAJA TAT'JANA GRIGOR'EVNA DENISJUK TAT'JANA ALEKSEEVNA |
| description | FIELD: medicine.SUBSTANCE: dermal flap is simulated in laboratory animals on the second day of experiment. Sildenafil 2.2 mg/kg is introduced intraperitoneally on the first, third and fifth day of the experiment.EFFECT: dermal flap survival rate in reduced circulation with no side effects.1 tbl, 1 ex
Изобретение относится к медицине, в частности к экспериментальной фармакологии, и может быть использовано для коррекции ишемии. Для этого лабораторным животным моделируют кожный лоскут на вторые сутки эксперимента. На первые третьи и пятые сутки эксперимента внутрибрюшинно вводят силденафил в дозе 2,2 мг/кг. Способ обеспечивает увеличение выживаемости кожного лоскута в условиях редуцированного кровообращения при отсутствии побочных эффектов, в т.ч. за счет разработанного режима введения препарата в специфических условиях эксперимента. 1 табл., 1 пр. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2498414C1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2498414C1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2498414C13</originalsourceid><addsrcrecordid>eNrjZPD1dQ3x8HdRcPMPUnBxDfJ19FFw83EMUAgODQrzDAPy3IP8w0M8FDz9FIJcXUKdXV0UnD2DnEN9HEM8_f0Uwj2BcsGePi6ufo5unj48DKxpiTnFqbxQmptBwc01xNlDN7UgPz61uCAxOTUvtSQ-KNTIxNLCxNDE2dCYCCUAjtAuAg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD FOR DERMAL FLAP SURVIVAL GROWTH IN REDUCED CIRCULATION WITH SILDENAFIL</title><source>esp@cenet</source><creator>KOCHKAROV VLADIMIR ISKHAKOVICH ; GUDYREV OLEG SERGEEVICH ; EFREMENKOVA DAR'JA AFONAS'EVNA ; LAZARENKO VIKTOR ANATOL'EVICH ; ZHERNAKOVA NINA IVANOVNA ; ARUSTAMOVA ANNA ALEKSANDROVNA ; KOLESNIK INGA MIKHAJLOVNA ; DANILENKO LJUDMILA MIKHAJLOVNA ; MOLCHANOVA OL'GA VIKTOROVNA ; JAKUSHEV VLADIMIR VLADIMIROVICH ; POKROVSKIJ MIKHAIL VLADIMIROVICH ; DOLZHIKOV ALEKSANDR ANATOL'EVICH ; KHODOV SERGEJ VLADIMIROVICH ; ALEKHIN SERGEJ ALEKSANDROVICH ; GUREEV VLADIMIR VLADIMIROVICH ; DOLZHIKOVA IRINA NIKOLAEVNA ; POKROVSKAJA TAT'JANA GRIGOR'EVNA ; DENISJUK TAT'JANA ALEKSEEVNA</creator><creatorcontrib>KOCHKAROV VLADIMIR ISKHAKOVICH ; GUDYREV OLEG SERGEEVICH ; EFREMENKOVA DAR'JA AFONAS'EVNA ; LAZARENKO VIKTOR ANATOL'EVICH ; ZHERNAKOVA NINA IVANOVNA ; ARUSTAMOVA ANNA ALEKSANDROVNA ; KOLESNIK INGA MIKHAJLOVNA ; DANILENKO LJUDMILA MIKHAJLOVNA ; MOLCHANOVA OL'GA VIKTOROVNA ; JAKUSHEV VLADIMIR VLADIMIROVICH ; POKROVSKIJ MIKHAIL VLADIMIROVICH ; DOLZHIKOV ALEKSANDR ANATOL'EVICH ; KHODOV SERGEJ VLADIMIROVICH ; ALEKHIN SERGEJ ALEKSANDROVICH ; GUREEV VLADIMIR VLADIMIROVICH ; DOLZHIKOVA IRINA NIKOLAEVNA ; POKROVSKAJA TAT'JANA GRIGOR'EVNA ; DENISJUK TAT'JANA ALEKSEEVNA</creatorcontrib><description>FIELD: medicine.SUBSTANCE: dermal flap is simulated in laboratory animals on the second day of experiment. Sildenafil 2.2 mg/kg is introduced intraperitoneally on the first, third and fifth day of the experiment.EFFECT: dermal flap survival rate in reduced circulation with no side effects.1 tbl, 1 ex
Изобретение относится к медицине, в частности к экспериментальной фармакологии, и может быть использовано для коррекции ишемии. Для этого лабораторным животным моделируют кожный лоскут на вторые сутки эксперимента. На первые третьи и пятые сутки эксперимента внутрибрюшинно вводят силденафил в дозе 2,2 мг/кг. Способ обеспечивает увеличение выживаемости кожного лоскута в условиях редуцированного кровообращения при отсутствии побочных эффектов, в т.ч. за счет разработанного режима введения препарата в специфических условиях эксперимента. 1 табл., 1 пр.</description><language>eng ; rus</language><subject>ADVERTISING ; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE ; CRYPTOGRAPHY ; DIAGRAMS ; DISPLAY ; EDUCATION ; EDUCATIONAL OR DEMONSTRATION APPLIANCES ; GLOBES ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PHYSICS ; PLANETARIA ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SEALS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131110&DB=EPODOC&CC=RU&NR=2498414C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20131110&DB=EPODOC&CC=RU&NR=2498414C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KOCHKAROV VLADIMIR ISKHAKOVICH</creatorcontrib><creatorcontrib>GUDYREV OLEG SERGEEVICH</creatorcontrib><creatorcontrib>EFREMENKOVA DAR'JA AFONAS'EVNA</creatorcontrib><creatorcontrib>LAZARENKO VIKTOR ANATOL'EVICH</creatorcontrib><creatorcontrib>ZHERNAKOVA NINA IVANOVNA</creatorcontrib><creatorcontrib>ARUSTAMOVA ANNA ALEKSANDROVNA</creatorcontrib><creatorcontrib>KOLESNIK INGA MIKHAJLOVNA</creatorcontrib><creatorcontrib>DANILENKO LJUDMILA MIKHAJLOVNA</creatorcontrib><creatorcontrib>MOLCHANOVA OL'GA VIKTOROVNA</creatorcontrib><creatorcontrib>JAKUSHEV VLADIMIR VLADIMIROVICH</creatorcontrib><creatorcontrib>POKROVSKIJ MIKHAIL VLADIMIROVICH</creatorcontrib><creatorcontrib>DOLZHIKOV ALEKSANDR ANATOL'EVICH</creatorcontrib><creatorcontrib>KHODOV SERGEJ VLADIMIROVICH</creatorcontrib><creatorcontrib>ALEKHIN SERGEJ ALEKSANDROVICH</creatorcontrib><creatorcontrib>GUREEV VLADIMIR VLADIMIROVICH</creatorcontrib><creatorcontrib>DOLZHIKOVA IRINA NIKOLAEVNA</creatorcontrib><creatorcontrib>POKROVSKAJA TAT'JANA GRIGOR'EVNA</creatorcontrib><creatorcontrib>DENISJUK TAT'JANA ALEKSEEVNA</creatorcontrib><title>METHOD FOR DERMAL FLAP SURVIVAL GROWTH IN REDUCED CIRCULATION WITH SILDENAFIL</title><description>FIELD: medicine.SUBSTANCE: dermal flap is simulated in laboratory animals on the second day of experiment. Sildenafil 2.2 mg/kg is introduced intraperitoneally on the first, third and fifth day of the experiment.EFFECT: dermal flap survival rate in reduced circulation with no side effects.1 tbl, 1 ex
Изобретение относится к медицине, в частности к экспериментальной фармакологии, и может быть использовано для коррекции ишемии. Для этого лабораторным животным моделируют кожный лоскут на вторые сутки эксперимента. На первые третьи и пятые сутки эксперимента внутрибрюшинно вводят силденафил в дозе 2,2 мг/кг. Способ обеспечивает увеличение выживаемости кожного лоскута в условиях редуцированного кровообращения при отсутствии побочных эффектов, в т.ч. за счет разработанного режима введения препарата в специфических условиях эксперимента. 1 табл., 1 пр.</description><subject>ADVERTISING</subject><subject>APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE</subject><subject>CRYPTOGRAPHY</subject><subject>DIAGRAMS</subject><subject>DISPLAY</subject><subject>EDUCATION</subject><subject>EDUCATIONAL OR DEMONSTRATION APPLIANCES</subject><subject>GLOBES</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PHYSICS</subject><subject>PLANETARIA</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SEALS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPD1dQ3x8HdRcPMPUnBxDfJ19FFw83EMUAgODQrzDAPy3IP8w0M8FDz9FIJcXUKdXV0UnD2DnEN9HEM8_f0Uwj2BcsGePi6ufo5unj48DKxpiTnFqbxQmptBwc01xNlDN7UgPz61uCAxOTUvtSQ-KNTIxNLCxNDE2dCYCCUAjtAuAg</recordid><startdate>20131110</startdate><enddate>20131110</enddate><creator>KOCHKAROV VLADIMIR ISKHAKOVICH</creator><creator>GUDYREV OLEG SERGEEVICH</creator><creator>EFREMENKOVA DAR'JA AFONAS'EVNA</creator><creator>LAZARENKO VIKTOR ANATOL'EVICH</creator><creator>ZHERNAKOVA NINA IVANOVNA</creator><creator>ARUSTAMOVA ANNA ALEKSANDROVNA</creator><creator>KOLESNIK INGA MIKHAJLOVNA</creator><creator>DANILENKO LJUDMILA MIKHAJLOVNA</creator><creator>MOLCHANOVA OL'GA VIKTOROVNA</creator><creator>JAKUSHEV VLADIMIR VLADIMIROVICH</creator><creator>POKROVSKIJ MIKHAIL VLADIMIROVICH</creator><creator>DOLZHIKOV ALEKSANDR ANATOL'EVICH</creator><creator>KHODOV SERGEJ VLADIMIROVICH</creator><creator>ALEKHIN SERGEJ ALEKSANDROVICH</creator><creator>GUREEV VLADIMIR VLADIMIROVICH</creator><creator>DOLZHIKOVA IRINA NIKOLAEVNA</creator><creator>POKROVSKAJA TAT'JANA GRIGOR'EVNA</creator><creator>DENISJUK TAT'JANA ALEKSEEVNA</creator><scope>EVB</scope></search><sort><creationdate>20131110</creationdate><title>METHOD FOR DERMAL FLAP SURVIVAL GROWTH IN REDUCED CIRCULATION WITH SILDENAFIL</title><author>KOCHKAROV VLADIMIR ISKHAKOVICH ; GUDYREV OLEG SERGEEVICH ; EFREMENKOVA DAR'JA AFONAS'EVNA ; LAZARENKO VIKTOR ANATOL'EVICH ; ZHERNAKOVA NINA IVANOVNA ; ARUSTAMOVA ANNA ALEKSANDROVNA ; KOLESNIK INGA MIKHAJLOVNA ; DANILENKO LJUDMILA MIKHAJLOVNA ; MOLCHANOVA OL'GA VIKTOROVNA ; JAKUSHEV VLADIMIR VLADIMIROVICH ; POKROVSKIJ MIKHAIL VLADIMIROVICH ; DOLZHIKOV ALEKSANDR ANATOL'EVICH ; KHODOV SERGEJ VLADIMIROVICH ; ALEKHIN SERGEJ ALEKSANDROVICH ; GUREEV VLADIMIR VLADIMIROVICH ; DOLZHIKOVA IRINA NIKOLAEVNA ; POKROVSKAJA TAT'JANA GRIGOR'EVNA ; DENISJUK TAT'JANA ALEKSEEVNA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2498414C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2013</creationdate><topic>ADVERTISING</topic><topic>APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE</topic><topic>CRYPTOGRAPHY</topic><topic>DIAGRAMS</topic><topic>DISPLAY</topic><topic>EDUCATION</topic><topic>EDUCATIONAL OR DEMONSTRATION APPLIANCES</topic><topic>GLOBES</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PHYSICS</topic><topic>PLANETARIA</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SEALS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KOCHKAROV VLADIMIR ISKHAKOVICH</creatorcontrib><creatorcontrib>GUDYREV OLEG SERGEEVICH</creatorcontrib><creatorcontrib>EFREMENKOVA DAR'JA AFONAS'EVNA</creatorcontrib><creatorcontrib>LAZARENKO VIKTOR ANATOL'EVICH</creatorcontrib><creatorcontrib>ZHERNAKOVA NINA IVANOVNA</creatorcontrib><creatorcontrib>ARUSTAMOVA ANNA ALEKSANDROVNA</creatorcontrib><creatorcontrib>KOLESNIK INGA MIKHAJLOVNA</creatorcontrib><creatorcontrib>DANILENKO LJUDMILA MIKHAJLOVNA</creatorcontrib><creatorcontrib>MOLCHANOVA OL'GA VIKTOROVNA</creatorcontrib><creatorcontrib>JAKUSHEV VLADIMIR VLADIMIROVICH</creatorcontrib><creatorcontrib>POKROVSKIJ MIKHAIL VLADIMIROVICH</creatorcontrib><creatorcontrib>DOLZHIKOV ALEKSANDR ANATOL'EVICH</creatorcontrib><creatorcontrib>KHODOV SERGEJ VLADIMIROVICH</creatorcontrib><creatorcontrib>ALEKHIN SERGEJ ALEKSANDROVICH</creatorcontrib><creatorcontrib>GUREEV VLADIMIR VLADIMIROVICH</creatorcontrib><creatorcontrib>DOLZHIKOVA IRINA NIKOLAEVNA</creatorcontrib><creatorcontrib>POKROVSKAJA TAT'JANA GRIGOR'EVNA</creatorcontrib><creatorcontrib>DENISJUK TAT'JANA ALEKSEEVNA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KOCHKAROV VLADIMIR ISKHAKOVICH</au><au>GUDYREV OLEG SERGEEVICH</au><au>EFREMENKOVA DAR'JA AFONAS'EVNA</au><au>LAZARENKO VIKTOR ANATOL'EVICH</au><au>ZHERNAKOVA NINA IVANOVNA</au><au>ARUSTAMOVA ANNA ALEKSANDROVNA</au><au>KOLESNIK INGA MIKHAJLOVNA</au><au>DANILENKO LJUDMILA MIKHAJLOVNA</au><au>MOLCHANOVA OL'GA VIKTOROVNA</au><au>JAKUSHEV VLADIMIR VLADIMIROVICH</au><au>POKROVSKIJ MIKHAIL VLADIMIROVICH</au><au>DOLZHIKOV ALEKSANDR ANATOL'EVICH</au><au>KHODOV SERGEJ VLADIMIROVICH</au><au>ALEKHIN SERGEJ ALEKSANDROVICH</au><au>GUREEV VLADIMIR VLADIMIROVICH</au><au>DOLZHIKOVA IRINA NIKOLAEVNA</au><au>POKROVSKAJA TAT'JANA GRIGOR'EVNA</au><au>DENISJUK TAT'JANA ALEKSEEVNA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR DERMAL FLAP SURVIVAL GROWTH IN REDUCED CIRCULATION WITH SILDENAFIL</title><date>2013-11-10</date><risdate>2013</risdate><abstract>FIELD: medicine.SUBSTANCE: dermal flap is simulated in laboratory animals on the second day of experiment. Sildenafil 2.2 mg/kg is introduced intraperitoneally on the first, third and fifth day of the experiment.EFFECT: dermal flap survival rate in reduced circulation with no side effects.1 tbl, 1 ex
Изобретение относится к медицине, в частности к экспериментальной фармакологии, и может быть использовано для коррекции ишемии. Для этого лабораторным животным моделируют кожный лоскут на вторые сутки эксперимента. На первые третьи и пятые сутки эксперимента внутрибрюшинно вводят силденафил в дозе 2,2 мг/кг. Способ обеспечивает увеличение выживаемости кожного лоскута в условиях редуцированного кровообращения при отсутствии побочных эффектов, в т.ч. за счет разработанного режима введения препарата в специфических условиях эксперимента. 1 табл., 1 пр.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; rus |
| recordid | cdi_epo_espacenet_RU2498414C1 |
| source | esp@cenet |
| subjects | ADVERTISING APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND,DEAF OR MUTE CRYPTOGRAPHY DIAGRAMS DISPLAY EDUCATION EDUCATIONAL OR DEMONSTRATION APPLIANCES GLOBES HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PHYSICS PLANETARIA PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEALS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD FOR DERMAL FLAP SURVIVAL GROWTH IN REDUCED CIRCULATION WITH SILDENAFIL |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T16%3A25%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KOCHKAROV%20VLADIMIR%20ISKHAKOVICH&rft.date=2013-11-10&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ERU2498414C1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |