METHOD OF REDUCING CONTENT OF ENDOTOXIN IN SAMPLE CONTAINING POLYSIALIC ACID AND ENDOTOXIN
FIELD: chemistry.SUBSTANCE: invention relates to biochemistry. A base having pKa 12-13 is added to a sample and incubated for 5 minutes to 24 hours at temperature of 0-60°C. The sample is passed through an anion-exchange column, wherein polysialic acid (PSA) is adsorbed on an anion-exchange resin. T...
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