COMPOUNDS, ACTIVE TOWARDS PPAR (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR)
FIELD: chemistry. ^ SUBSTANCE: invention relates to a compound having structure ^ , radicals are as described in the formula of invention, as well as pharmaceutically-acceptable salt, prodrug, tautomer and stereoisomer thereof. The invention also relates to a composition, a set for modulating PPAR b...
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| creator | TSUKERMAN REBEKKA ARTIS DIN R UOMAK PATRIK LIN DZHEK VANG VEJRU ZHANG CHAO IBRAKHIM PRABKHA N LI B'JUNGKHUN SHI SHENGKHUA |
| description | FIELD: chemistry. ^ SUBSTANCE: invention relates to a compound having structure ^ , radicals are as described in the formula of invention, as well as pharmaceutically-acceptable salt, prodrug, tautomer and stereoisomer thereof. The invention also relates to a composition, a set for modulating PPAR based on said compound, a method of treating a patient suffering from a disease or condition or at risk of a disease or condition, for which PPAR modulation is therapeutically useful. ^ EFFECT: novel compounds which are active towards PPAR are obtained and described. ^ 41 cl, 622 ex, 8 tbl
Изобретение относится к соединению, имеющему структуру , значения радикалов такие, как представлено в формуле изобретения, а также к его фармацевтически приемлемой соли, пролекарству, таутомеру и стереоизомеру. Также изобретение относится к композиции, набору для модулирования PPAR, на основе этого соединения, к способу лечения субъекта, страдающего от заболевания или состояния или имеющего риск заболевания или состояния, для которого модуляция PPAR терапевтически полезна. Технический результат: получены и описаны новые соеднинения, которые активны в отношении PPAR. 6 н. и 35 з.п.ф-лы, 8 табл. |
| format | Patent |
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Изобретение относится к соединению, имеющему структуру , значения радикалов такие, как представлено в формуле изобретения, а также к его фармацевтически приемлемой соли, пролекарству, таутомеру и стереоизомеру. Также изобретение относится к композиции, набору для модулирования PPAR, на основе этого соединения, к способу лечения субъекта, страдающего от заболевания или состояния или имеющего риск заболевания или состояния, для которого модуляция PPAR терапевтически полезна. Технический результат: получены и описаны новые соеднинения, которые активны в отношении PPAR. 6 н. и 35 з.п.ф-лы, 8 табл.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPOUNDS, ACTIVE TOWARDS PPAR (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR) |
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