PEPTIDE LanA1, EXTRACTED FROM Bacterium bacillus LICHENIFORMIS VK21, HAVING ANTIMICROBIAL EFFECT
FIELD: medicine. ^ SUBSTANCE: biologically active peptide is proposed with the common formula: , where OBu - residue of 2-oxobutyric acid, Abu - residue of 2-aminobutyric acid, Dha - residue of 2,3-didehydroalanine, Dhb - residue of 2,3-didehydroaminobutyric acid, besides residues are in sequence li...
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| creator | OVCHINNIKOVA TAT'JANA VLADIMIROVNA NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA FINKINA EKATERINA IVANOVNA TAGAEV ANDREJ AZISOVICH BALANDIN SERGEJ VLADIMIROVICH JAKIMENKO ZOJA ALEKSANDROVNA SHENKAREV ZAKHAR OLEGOVICH ARSEN'EV ALEKSANDR SERGEEVICH TEMIROV JURIJ VITAL'EVICH |
| description | FIELD: medicine. ^ SUBSTANCE: biologically active peptide is proposed with the common formula: , where OBu - residue of 2-oxobutyric acid, Abu - residue of 2-aminobutyric acid, Dha - residue of 2,3-didehydroalanine, Dhb - residue of 2,3-didehydroaminobutyric acid, besides residues are in sequence linked with amide links, residues Abu3-Ala7, Abu22-Ala27 and Abu24-Ala31 are also linked pairwise with thioether links with formation of three residues of 3-methyllanthionine, residues Ala11-Ala21 are linked with thioether link to form residue of lanthionine. This peptide has antimicrobial effect at gram-positive bacteria Bacillus subtilis, strains L1 and 1621; Bacillus pumilus, strain 2001; Bacillus globigii, strain I; Bacillus amyloliquefaciens, strain I; Bacillus megaterium, strain VKM41; Mycobacterium smegmatis, strain 1171; Mycobacterium phlei, strain 1291; Micrococcus luteus, strain B 1314; Staphylococcus aureus, strain 209p; Rhodococcus sp., strain SSI. ^ EFFECT: increased efficiency of peptide antimicrobial action. ^ 4 dwg, 1 tbl, 6 ex
Изобретение относится к области биотехнологии. Предложен биологически активный пептид общей формулы: ! ! где ОВu - остаток 2-оксомасляной кислоты, Abu - остаток 2-аминомасляной кислоты, Dha - остаток 2,3-дидегидроаланина, Dhb - остаток 2,3-дидегидроаминомасляной кислоты, причем остатки в последовательности соединены амидными связями, остатки Abu3-Ala7, Abu22-Ala27 и Abu24-Ala31 также соединены попарно тиоэфирными связями с образованием трех остатков 3-метиллантионина, остатки Ala11-Ala21 соединены тиоэфирной связью с образованием остатка лантионина. Данный пептид обладает антимикробной активностью в отношении грамположительных бактерий Bacillus subtilis, штаммы L1 и 1621; Bacillus pumilus, штамм 2001; Bacillus globigii, штамм I; Bacillus amyloliquefaciens, штамм I; Bacillus megaterium, штамм VKM41; Mycobacterium smegmatis, штамм 1171; Mycobacterium phlei, штамм 1291; Micrococcus luteus, штамм В 1314; Staphylococcus aureus, штамм 209p; Rhodococcus sp., штамм SS1. 4 ил., 1 табл. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_RU2408732C1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>RU2408732C1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_RU2408732C13</originalsourceid><addsrcrecordid>eNqNy00OgjAQQGE2Lox6hzmAJgImui1lKhPLT2ol7rA2NSFBJBburwsP4OptvjcPbhVWmlIEaXoWrgGvWjGuMQWhyhwSY0f3bqcn3I1tu27yIIlnWJAoVU5nqE_R98pYTcURWKEpJ67KhJgEFAK5Xgazh-m8W_26CECg5tnGDa_G-cFY17uxUZdotz3s44iH8R_kAykqNPY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PEPTIDE LanA1, EXTRACTED FROM Bacterium bacillus LICHENIFORMIS VK21, HAVING ANTIMICROBIAL EFFECT</title><source>esp@cenet</source><creator>OVCHINNIKOVA TAT'JANA VLADIMIROVNA ; NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA ; FINKINA EKATERINA IVANOVNA ; TAGAEV ANDREJ AZISOVICH ; BALANDIN SERGEJ VLADIMIROVICH ; JAKIMENKO ZOJA ALEKSANDROVNA ; SHENKAREV ZAKHAR OLEGOVICH ; ARSEN'EV ALEKSANDR SERGEEVICH ; TEMIROV JURIJ VITAL'EVICH</creator><creatorcontrib>OVCHINNIKOVA TAT'JANA VLADIMIROVNA ; NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA ; FINKINA EKATERINA IVANOVNA ; TAGAEV ANDREJ AZISOVICH ; BALANDIN SERGEJ VLADIMIROVICH ; JAKIMENKO ZOJA ALEKSANDROVNA ; SHENKAREV ZAKHAR OLEGOVICH ; ARSEN'EV ALEKSANDR SERGEEVICH ; TEMIROV JURIJ VITAL'EVICH</creatorcontrib><description>FIELD: medicine. ^ SUBSTANCE: biologically active peptide is proposed with the common formula: , where OBu - residue of 2-oxobutyric acid, Abu - residue of 2-aminobutyric acid, Dha - residue of 2,3-didehydroalanine, Dhb - residue of 2,3-didehydroaminobutyric acid, besides residues are in sequence linked with amide links, residues Abu3-Ala7, Abu22-Ala27 and Abu24-Ala31 are also linked pairwise with thioether links with formation of three residues of 3-methyllanthionine, residues Ala11-Ala21 are linked with thioether link to form residue of lanthionine. This peptide has antimicrobial effect at gram-positive bacteria Bacillus subtilis, strains L1 and 1621; Bacillus pumilus, strain 2001; Bacillus globigii, strain I; Bacillus amyloliquefaciens, strain I; Bacillus megaterium, strain VKM41; Mycobacterium smegmatis, strain 1171; Mycobacterium phlei, strain 1291; Micrococcus luteus, strain B 1314; Staphylococcus aureus, strain 209p; Rhodococcus sp., strain SSI. ^ EFFECT: increased efficiency of peptide antimicrobial action. ^ 4 dwg, 1 tbl, 6 ex
Изобретение относится к области биотехнологии. Предложен биологически активный пептид общей формулы: ! ! где ОВu - остаток 2-оксомасляной кислоты, Abu - остаток 2-аминомасляной кислоты, Dha - остаток 2,3-дидегидроаланина, Dhb - остаток 2,3-дидегидроаминомасляной кислоты, причем остатки в последовательности соединены амидными связями, остатки Abu3-Ala7, Abu22-Ala27 и Abu24-Ala31 также соединены попарно тиоэфирными связями с образованием трех остатков 3-метиллантионина, остатки Ala11-Ala21 соединены тиоэфирной связью с образованием остатка лантионина. Данный пептид обладает антимикробной активностью в отношении грамположительных бактерий Bacillus subtilis, штаммы L1 и 1621; Bacillus pumilus, штамм 2001; Bacillus globigii, штамм I; Bacillus amyloliquefaciens, штамм I; Bacillus megaterium, штамм VKM41; Mycobacterium smegmatis, штамм 1171; Mycobacterium phlei, штамм 1291; Micrococcus luteus, штамм В 1314; Staphylococcus aureus, штамм 209p; Rhodococcus sp., штамм SS1. 4 ил., 1 табл.</description><language>eng ; rus</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOUNDS OF UNKNOWN CONSTITUTION ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROCESSES USING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110110&DB=EPODOC&CC=RU&NR=2408732C1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110110&DB=EPODOC&CC=RU&NR=2408732C1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OVCHINNIKOVA TAT'JANA VLADIMIROVNA</creatorcontrib><creatorcontrib>NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA</creatorcontrib><creatorcontrib>FINKINA EKATERINA IVANOVNA</creatorcontrib><creatorcontrib>TAGAEV ANDREJ AZISOVICH</creatorcontrib><creatorcontrib>BALANDIN SERGEJ VLADIMIROVICH</creatorcontrib><creatorcontrib>JAKIMENKO ZOJA ALEKSANDROVNA</creatorcontrib><creatorcontrib>SHENKAREV ZAKHAR OLEGOVICH</creatorcontrib><creatorcontrib>ARSEN'EV ALEKSANDR SERGEEVICH</creatorcontrib><creatorcontrib>TEMIROV JURIJ VITAL'EVICH</creatorcontrib><title>PEPTIDE LanA1, EXTRACTED FROM Bacterium bacillus LICHENIFORMIS VK21, HAVING ANTIMICROBIAL EFFECT</title><description>FIELD: medicine. ^ SUBSTANCE: biologically active peptide is proposed with the common formula: , where OBu - residue of 2-oxobutyric acid, Abu - residue of 2-aminobutyric acid, Dha - residue of 2,3-didehydroalanine, Dhb - residue of 2,3-didehydroaminobutyric acid, besides residues are in sequence linked with amide links, residues Abu3-Ala7, Abu22-Ala27 and Abu24-Ala31 are also linked pairwise with thioether links with formation of three residues of 3-methyllanthionine, residues Ala11-Ala21 are linked with thioether link to form residue of lanthionine. This peptide has antimicrobial effect at gram-positive bacteria Bacillus subtilis, strains L1 and 1621; Bacillus pumilus, strain 2001; Bacillus globigii, strain I; Bacillus amyloliquefaciens, strain I; Bacillus megaterium, strain VKM41; Mycobacterium smegmatis, strain 1171; Mycobacterium phlei, strain 1291; Micrococcus luteus, strain B 1314; Staphylococcus aureus, strain 209p; Rhodococcus sp., strain SSI. ^ EFFECT: increased efficiency of peptide antimicrobial action. ^ 4 dwg, 1 tbl, 6 ex
Изобретение относится к области биотехнологии. Предложен биологически активный пептид общей формулы: ! ! где ОВu - остаток 2-оксомасляной кислоты, Abu - остаток 2-аминомасляной кислоты, Dha - остаток 2,3-дидегидроаланина, Dhb - остаток 2,3-дидегидроаминомасляной кислоты, причем остатки в последовательности соединены амидными связями, остатки Abu3-Ala7, Abu22-Ala27 и Abu24-Ala31 также соединены попарно тиоэфирными связями с образованием трех остатков 3-метиллантионина, остатки Ala11-Ala21 соединены тиоэфирной связью с образованием остатка лантионина. Данный пептид обладает антимикробной активностью в отношении грамположительных бактерий Bacillus subtilis, штаммы L1 и 1621; Bacillus pumilus, штамм 2001; Bacillus globigii, штамм I; Bacillus amyloliquefaciens, штамм I; Bacillus megaterium, штамм VKM41; Mycobacterium smegmatis, штамм 1171; Mycobacterium phlei, штамм 1291; Micrococcus luteus, штамм В 1314; Staphylococcus aureus, штамм 209p; Rhodococcus sp., штамм SS1. 4 ил., 1 табл.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOUNDS OF UNKNOWN CONSTITUTION</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNy00OgjAQQGE2Lox6hzmAJgImui1lKhPLT2ol7rA2NSFBJBburwsP4OptvjcPbhVWmlIEaXoWrgGvWjGuMQWhyhwSY0f3bqcn3I1tu27yIIlnWJAoVU5nqE_R98pYTcURWKEpJ67KhJgEFAK5Xgazh-m8W_26CECg5tnGDa_G-cFY17uxUZdotz3s44iH8R_kAykqNPY</recordid><startdate>20110110</startdate><enddate>20110110</enddate><creator>OVCHINNIKOVA TAT'JANA VLADIMIROVNA</creator><creator>NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA</creator><creator>FINKINA EKATERINA IVANOVNA</creator><creator>TAGAEV ANDREJ AZISOVICH</creator><creator>BALANDIN SERGEJ VLADIMIROVICH</creator><creator>JAKIMENKO ZOJA ALEKSANDROVNA</creator><creator>SHENKAREV ZAKHAR OLEGOVICH</creator><creator>ARSEN'EV ALEKSANDR SERGEEVICH</creator><creator>TEMIROV JURIJ VITAL'EVICH</creator><scope>EVB</scope></search><sort><creationdate>20110110</creationdate><title>PEPTIDE LanA1, EXTRACTED FROM Bacterium bacillus LICHENIFORMIS VK21, HAVING ANTIMICROBIAL EFFECT</title><author>OVCHINNIKOVA TAT'JANA VLADIMIROVNA ; NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA ; FINKINA EKATERINA IVANOVNA ; TAGAEV ANDREJ AZISOVICH ; BALANDIN SERGEJ VLADIMIROVICH ; JAKIMENKO ZOJA ALEKSANDROVNA ; SHENKAREV ZAKHAR OLEGOVICH ; ARSEN'EV ALEKSANDR SERGEEVICH ; TEMIROV JURIJ VITAL'EVICH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_RU2408732C13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; rus</language><creationdate>2011</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOUNDS OF UNKNOWN CONSTITUTION</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>OVCHINNIKOVA TAT'JANA VLADIMIROVNA</creatorcontrib><creatorcontrib>NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA</creatorcontrib><creatorcontrib>FINKINA EKATERINA IVANOVNA</creatorcontrib><creatorcontrib>TAGAEV ANDREJ AZISOVICH</creatorcontrib><creatorcontrib>BALANDIN SERGEJ VLADIMIROVICH</creatorcontrib><creatorcontrib>JAKIMENKO ZOJA ALEKSANDROVNA</creatorcontrib><creatorcontrib>SHENKAREV ZAKHAR OLEGOVICH</creatorcontrib><creatorcontrib>ARSEN'EV ALEKSANDR SERGEEVICH</creatorcontrib><creatorcontrib>TEMIROV JURIJ VITAL'EVICH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OVCHINNIKOVA TAT'JANA VLADIMIROVNA</au><au>NURMUKHAMEDOVA EHLINA KURBAN-ALIEVNA</au><au>FINKINA EKATERINA IVANOVNA</au><au>TAGAEV ANDREJ AZISOVICH</au><au>BALANDIN SERGEJ VLADIMIROVICH</au><au>JAKIMENKO ZOJA ALEKSANDROVNA</au><au>SHENKAREV ZAKHAR OLEGOVICH</au><au>ARSEN'EV ALEKSANDR SERGEEVICH</au><au>TEMIROV JURIJ VITAL'EVICH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PEPTIDE LanA1, EXTRACTED FROM Bacterium bacillus LICHENIFORMIS VK21, HAVING ANTIMICROBIAL EFFECT</title><date>2011-01-10</date><risdate>2011</risdate><abstract>FIELD: medicine. ^ SUBSTANCE: biologically active peptide is proposed with the common formula: , where OBu - residue of 2-oxobutyric acid, Abu - residue of 2-aminobutyric acid, Dha - residue of 2,3-didehydroalanine, Dhb - residue of 2,3-didehydroaminobutyric acid, besides residues are in sequence linked with amide links, residues Abu3-Ala7, Abu22-Ala27 and Abu24-Ala31 are also linked pairwise with thioether links with formation of three residues of 3-methyllanthionine, residues Ala11-Ala21 are linked with thioether link to form residue of lanthionine. This peptide has antimicrobial effect at gram-positive bacteria Bacillus subtilis, strains L1 and 1621; Bacillus pumilus, strain 2001; Bacillus globigii, strain I; Bacillus amyloliquefaciens, strain I; Bacillus megaterium, strain VKM41; Mycobacterium smegmatis, strain 1171; Mycobacterium phlei, strain 1291; Micrococcus luteus, strain B 1314; Staphylococcus aureus, strain 209p; Rhodococcus sp., strain SSI. ^ EFFECT: increased efficiency of peptide antimicrobial action. ^ 4 dwg, 1 tbl, 6 ex
Изобретение относится к области биотехнологии. Предложен биологически активный пептид общей формулы: ! ! где ОВu - остаток 2-оксомасляной кислоты, Abu - остаток 2-аминомасляной кислоты, Dha - остаток 2,3-дидегидроаланина, Dhb - остаток 2,3-дидегидроаминомасляной кислоты, причем остатки в последовательности соединены амидными связями, остатки Abu3-Ala7, Abu22-Ala27 и Abu24-Ala31 также соединены попарно тиоэфирными связями с образованием трех остатков 3-метиллантионина, остатки Ala11-Ala21 соединены тиоэфирной связью с образованием остатка лантионина. Данный пептид обладает антимикробной активностью в отношении грамположительных бактерий Bacillus subtilis, штаммы L1 и 1621; Bacillus pumilus, штамм 2001; Bacillus globigii, штамм I; Bacillus amyloliquefaciens, штамм I; Bacillus megaterium, штамм VKM41; Mycobacterium smegmatis, штамм 1171; Mycobacterium phlei, штамм 1291; Micrococcus luteus, штамм В 1314; Staphylococcus aureus, штамм 209p; Rhodococcus sp., штамм SS1. 4 ил., 1 табл.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOUNDS OF UNKNOWN CONSTITUTION ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | PEPTIDE LanA1, EXTRACTED FROM Bacterium bacillus LICHENIFORMIS VK21, HAVING ANTIMICROBIAL EFFECT |
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