ANTIBODIES TO P-SELECTIN
FIELD: medicine. ^ SUBSTANCE: there described are antibodies to P-selectin and namely antibodies to P-selectin and their versions which include Fc-portion of human origin and do not bind Clq complement factor. There specified is pharmaceutical composition containing the above antibody. ^ EFFECT: pos...
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| creator | SHTRAJN PAMELA SHTUBENRAUKH KAJ-GUNNAR JANSEN-MOLENAR MIRANDA SHTAJNER BEAT VAN-VUGT MARTINE GRAUS IVO VAN-DE-VINKEL JAN IMBER ZHAK KLING DOROTE REBERS FRANK SHTERN ANNE PARREN PAUL KOPETTSKI EHRKHARD |
| description | FIELD: medicine. ^ SUBSTANCE: there described are antibodies to P-selectin and namely antibodies to P-selectin and their versions which include Fc-portion of human origin and do not bind Clq complement factor. There specified is pharmaceutical composition containing the above antibody. ^ EFFECT: possibility of being used for treatment of the patient suffering critical ischemia of limbs or occlusive disease of peripheral arteries(CIL/ODPA). ^ 4 cl, 10 dwg, 6 tbl
Изобретение относится к биотехнологии. Описаны антитела к Р-селектину и, в частности, антитела к Р-селектину и их варианты, которые включают Fc-часть человеческого происхождения и не связывают фактор комплемента Clq. Представлена фармацевтическая композиция, содержащая описанное антитело. Изобретение может быть использовано для лечения пациента, страдающего от критической ишемии конечностей или окклюзионной болезни периферических артерий (КИК/ОБПА). 2 н. и 2 з.п. ф-лы, 10 ил., 6 табл. |
| format | Patent |
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Изобретение относится к биотехнологии. Описаны антитела к Р-селектину и, в частности, антитела к Р-селектину и их варианты, которые включают Fc-часть человеческого происхождения и не связывают фактор комплемента Clq. Представлена фармацевтическая композиция, содержащая описанное антитело. Изобретение может быть использовано для лечения пациента, страдающего от критической ишемии конечностей или окклюзионной болезни периферических артерий (КИК/ОБПА). 2 н. и 2 з.п. ф-лы, 10 ил., 6 табл.</description><language>eng ; rus</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090927&DB=EPODOC&CC=RU&NR=2368622C2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090927&DB=EPODOC&CC=RU&NR=2368622C2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHTRAJN PAMELA</creatorcontrib><creatorcontrib>SHTUBENRAUKH KAJ-GUNNAR</creatorcontrib><creatorcontrib>JANSEN-MOLENAR MIRANDA</creatorcontrib><creatorcontrib>SHTAJNER BEAT</creatorcontrib><creatorcontrib>VAN-VUGT MARTINE</creatorcontrib><creatorcontrib>GRAUS IVO</creatorcontrib><creatorcontrib>VAN-DE-VINKEL JAN</creatorcontrib><creatorcontrib>IMBER ZHAK</creatorcontrib><creatorcontrib>KLING DOROTE</creatorcontrib><creatorcontrib>REBERS FRANK</creatorcontrib><creatorcontrib>SHTERN ANNE</creatorcontrib><creatorcontrib>PARREN PAUL</creatorcontrib><creatorcontrib>KOPETTSKI EHRKHARD</creatorcontrib><title>ANTIBODIES TO P-SELECTIN</title><description>FIELD: medicine. ^ SUBSTANCE: there described are antibodies to P-selectin and namely antibodies to P-selectin and their versions which include Fc-portion of human origin and do not bind Clq complement factor. There specified is pharmaceutical composition containing the above antibody. ^ EFFECT: possibility of being used for treatment of the patient suffering critical ischemia of limbs or occlusive disease of peripheral arteries(CIL/ODPA). ^ 4 cl, 10 dwg, 6 tbl
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Изобретение относится к биотехнологии. Описаны антитела к Р-селектину и, в частности, антитела к Р-селектину и их варианты, которые включают Fc-часть человеческого происхождения и не связывают фактор комплемента Clq. Представлена фармацевтическая композиция, содержащая описанное антитело. Изобретение может быть использовано для лечения пациента, страдающего от критической ишемии конечностей или окклюзионной болезни периферических артерий (КИК/ОБПА). 2 н. и 2 з.п. ф-лы, 10 ил., 6 табл.</abstract><oa>free_for_read</oa></addata></record> |
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| title | ANTIBODIES TO P-SELECTIN |
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