AGENTS WITH HEMORHEOLOGICAL, ANTIAGGREGANT AND ANTITROMBOGENIC ACTIVITY

FIELD: medicine; pharmacology. ^ SUBSTANCE: it is suggested to apply 2-methyl-6-isobornyl phenol, 4-methyl-2.6-diisobornyl phenol or 2-(dibutylamino)methyl-4-methyl-6-isobornyl phenol hydrochloride as agents with hemorheological, antiaggregant and antitrombogenic activity. ^ EFFECT: limitation of er...

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Hauptverfasser:	IVANOV IVAN SERGEEVICH, KRASNOV EFIM AVRAAMOVICH, SMOL'JAKOVA VERA IVANOVNA, CHUKICHEVA IRINA JUR'EVNA, PLOTNIKOV MARK BORISOVICH, BURAVLEV EVGENIJ VLADIMIROVICH, KUCHIN ALEKSANDR VASIL'EVICH
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine; pharmacology. ^ SUBSTANCE: it is suggested to apply 2-methyl-6-isobornyl phenol, 4-methyl-2.6-diisobornyl phenol or 2-(dibutylamino)methyl-4-methyl-6-isobornyl phenol hydrochloride as agents with hemorheological, antiaggregant and antitrombogenic activity. ^ EFFECT: limitation of erythrocytes aggregation amplification in model of blood hyperviscosity, expressed antiaggregant activity in case of ADP-induced aggregation of platelets and reduction of thrombus mass compared to control in case of blood flow reduction in artery. ^ 5 tbl, 25 ex