1-(3-DIETHYLAMINOPROPYL)-2-(4-FLUOROPHENYL)-IMIDAZO[1,2-a]BENZIMIDAZOLE DIHYDROCHLORIDE ELICITING LOCAL ANESTHETIC EFFECT

FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention relates to a novel 1,2-disubstituted derivative of imidazo[1,2-a]imidazole. Invention describes 1-(3-diethylaminopropyl)-2-4-fluorophenyl)-imidazo[1,2-a]benzimidazole of the formula (I): . Compound elicits local anesthetic effect in surface...

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Hauptverfasser: MINKIN VLADIMIR ISAAKOVICH, FUTORJANSKAJA TAMARA NIKOLAEVNA, ANISIMOVA VERA ALEKSEEVNA, GALENKO-JAROSHEVSKIJ ALEKSANDR PAVLOVICH, VARLASHKINA INESSA ALEKSANDROVNA, TOLPYGIN IVAN EVGEN'EVICH, ZHUKOV ALEKSEJ VASIL'EVICH, LUGOVAJA IRINA ANATOL'EVNA, TLISHEVA ZAREMA SHUMAFOVNA, USOV ALEKSANDR VALER'EVICH
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creator MINKIN VLADIMIR ISAAKOVICH
FUTORJANSKAJA TAMARA NIKOLAEVNA
ANISIMOVA VERA ALEKSEEVNA
GALENKO-JAROSHEVSKIJ ALEKSANDR PAVLOVICH
VARLASHKINA INESSA ALEKSANDROVNA
TOLPYGIN IVAN EVGEN'EVICH
ZHUKOV ALEKSEJ VASIL'EVICH
LUGOVAJA IRINA ANATOL'EVNA
TLISHEVA ZAREMA SHUMAFOVNA
USOV ALEKSANDR VALER'EVICH
description FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention relates to a novel 1,2-disubstituted derivative of imidazo[1,2-a]imidazole. Invention describes 1-(3-diethylaminopropyl)-2-4-fluorophenyl)-imidazo[1,2-a]benzimidazole of the formula (I): . Compound elicits local anesthetic effect in surface (terminal), infiltration, conduction and epidural anesthesia. Invention provides synthesis of a novel compound possessing useful biological properties. ^ EFFECT: valuable medicinal properties of compounds. ^ 6 tbl, 1 ex
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title 1-(3-DIETHYLAMINOPROPYL)-2-(4-FLUOROPHENYL)-IMIDAZO[1,2-a]BENZIMIDAZOLE DIHYDROCHLORIDE ELICITING LOCAL ANESTHETIC EFFECT
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