POLYCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION POSSESSING PROPERTY OF H3 RECEPTOR ANTAGONIST AND METHOD FOR TREATMENT BY ITS USING

FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to novel polycyclic compounds of the formula (I): wherein radicals and symbols have values given in the invention claim. Compounds of the formula (I) possess properties of H3 receptors antagonist. Also, invention relates to...

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Hauptverfasser: MANGIARASINA P'ETRO, BOJS KRISTOFER V, ASLANJAN ROBERT DZH, MAK KORMIK KEVIN D, ROZENBLJUM STJUART B, SHIKH NENG-JANG, TING POULIN K, TOM VING K, BERLIN MAJKL J, MUTAKHI MVANGI VA, PIVINSKI DZHON DZH
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creator MANGIARASINA P'ETRO
BOJS KRISTOFER V
ASLANJAN ROBERT DZH
MAK KORMIK KEVIN D
ROZENBLJUM STJUART B
SHIKH NENG-JANG
TING POULIN K
TOM VING K
BERLIN MAJKL J
MUTAKHI MVANGI VA
PIVINSKI DZHON DZH
description FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to novel polycyclic compounds of the formula (I): wherein radicals and symbols have values given in the invention claim. Compounds of the formula (I) possess properties of H3 receptors antagonist. Also, invention relates to a pharmaceutical composition containing compounds of the formula (I). Also, invention relates to a method for treatment of disease of group comprising difficulty in nasal breath, obesity, somnolence, narcolepsy, attention deficiency with hyperactivity, Alzheimer's disease and schizophrenia that involves using compounds of the formula (I) and, optionally, in combination of H receptor antagonist. ^ EFFECT: valuable medicinal properties of compound and pharmaceutical composition. ^ 39 cl, 3 tbl, 31 ex
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title POLYCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION POSSESSING PROPERTY OF H3 RECEPTOR ANTAGONIST AND METHOD FOR TREATMENT BY ITS USING
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