METHOD FOR PREPARING SUBSTANCE POSSESSING NOOTROPIC ACTIVITY

METHOD FOR PREPARING SUBSTANCE POSSESSING NOOTROPIC ACTIVITY

FIELD: medicine, pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to a method for preparing rosavine possessing the nootropic activity. Method for preparing rosavine involves three-fold extraction of rosewort (Rhodiola rosea L.) milled rhizomes with 70-90% ethyl alcohol in the defin...

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Hauptverfasser: DUBISHCHEV ALEKSEJ VLADIMIROVICH, KURKIN VLADIMIR ALEKSANDROVICH, EZHKOV VLADIMIR NIKOLAEVICH, TITOVA IRINA NIKOLAEVNA
Format: Patent
Sprache:eng ; rus
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator DUBISHCHEV ALEKSEJ VLADIMIROVICH
KURKIN VLADIMIR ALEKSANDROVICH
EZHKOV VLADIMIR NIKOLAEVICH
TITOVA IRINA NIKOLAEVNA
description FIELD: medicine, pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to a method for preparing rosavine possessing the nootropic activity. Method for preparing rosavine involves three-fold extraction of rosewort (Rhodiola rosea L.) milled rhizomes with 70-90% ethyl alcohol in the definite ratio raw : extractant, evaporation of combined extracts under vacuum to obtain dense residue, chromatography separation on silica gel, evaporation of eluates and crystallization wherein the first extraction is carried out at definite temperature and two other extractions are carried out at definite temperature with reflux condenser. Proposed method provides increasing the yield of the end product from rosewort rhizomes and reducing duration of the technological process. ^ EFFECT: improved preparing method. ^ 3 tbl, 3 ex
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD FOR PREPARING SUBSTANCE POSSESSING NOOTROPIC ACTIVITY
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