METHOD FOR CORRECTING AFFECTED ERYTHROPOIESIS AT EXPERIMENTAL HYPOXIA

FIELD: medicine, pharmacology. ^ SUBSTANCE: the present innovation deals with correcting affected erythropoiesis in case of severe hypoxia. One should fulfill subcutaneous single injection of propranolol for laboratory mice on the 2nd d after hypoxia modeling at the dosage of 5 mg/kg. The innovation...

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Hauptverfasser: GOL'DBERG EVGENIJ DANILOVICH, DYGAJ ALEKSANDR MIKHAJLOVICH, ZJUZ'KOV GLEB NIKOLAEVICH
Format: Patent
Sprache:eng ; rus
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Zusammenfassung:FIELD: medicine, pharmacology. ^ SUBSTANCE: the present innovation deals with correcting affected erythropoiesis in case of severe hypoxia. One should fulfill subcutaneous single injection of propranolol for laboratory mice on the 2nd d after hypoxia modeling at the dosage of 5 mg/kg. The innovation enables to improve the dynamics for reconstructing cellularity and qualitative values of erythroid source of blood formation, increase the number of erythrocytes in peripheral blood at decreasing the production of their pathological forms due to preventing the lesion of commitment precursor cells of erythropoiesis in post-hypoxic period. ^ EFFECT: higher efficiency of correction. ^ 3 ex, 3 tbl