NEW COMPOSITION FOR ORAL ADMINISTRATION

FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a solid pharmaceutical composition. The composition comprises tegaserod or its salts as an active component that is sensitive to acid effect and/or difficultly soluble in water, and a loosening agent taken in the amount at least 15 wt.-% a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	PFANNKUKHE KHANS-JURGEN, TSJUGER OTMAR, DE-BRUEJN KAREL, EHNGEL' GJUNTER, TEVISSEN MIKHAEHL, VITZLENG KRISTIAN
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to a solid pharmaceutical composition. The composition comprises tegaserod or its salts as an active component that is sensitive to acid effect and/or difficultly soluble in water, and a loosening agent taken in the amount at least 15 wt.-% as measured for the total mass of the composition. The composition is stable and can be prepared easily, it shows good rate release after its administration patients and good biological availability. The composition is designated for prophylaxis, modulation or treatment of visceral pain or discomfort, for modulation of visceral sensitivity or perception, improvement of sensory perception of rectum intestine tension and for treatment of anal dysfunction regulation. ^ EFFECT: improved and valuable medicinal properties of composition. ^ 14 cl, 7 ex