HUMAN IMMUNOGLOBULIN SHOWING SPECIFICITY TO HUMAN PROTEIN L-SELECTIN

biotechnology. SUBSTANCE: human immunoglobulin showing specificity to human protein L-selectin is chimeric immunoglobulin having regions that determine complementarity (CDR) corresponding to CDR-regions of murine donor immunoglobulin and carcass regions of variable site of heavy and light chain of h...

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description biotechnology. SUBSTANCE: human immunoglobulin showing specificity to human protein L-selectin is chimeric immunoglobulin having regions that determine complementarity (CDR) corresponding to CDR-regions of murine donor immunoglobulin and carcass regions of variable site of heavy and light chain of human acceptor immunoglobulin and specifically binding with human L-selectin (affinity constant is 107M-1). Invention ensures to prepare nonimmunogeneous for human immunoglobulin showing specificity to protein L-selectin. EFFECT: improved method of preparing. 19 cl, 1 tbl, 6 dwg, 5 ex
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SUBSTANCE: human immunoglobulin showing specificity to human protein L-selectin is chimeric immunoglobulin having regions that determine complementarity (CDR) corresponding to CDR-regions of murine donor immunoglobulin and carcass regions of variable site of heavy and light chain of human acceptor immunoglobulin and specifically binding with human L-selectin (affinity constant is 107M-1). Invention ensures to prepare nonimmunogeneous for human immunoglobulin showing specificity to protein L-selectin. 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SUBSTANCE: human immunoglobulin showing specificity to human protein L-selectin is chimeric immunoglobulin having regions that determine complementarity (CDR) corresponding to CDR-regions of murine donor immunoglobulin and carcass regions of variable site of heavy and light chain of human acceptor immunoglobulin and specifically binding with human L-selectin (affinity constant is 107M-1). Invention ensures to prepare nonimmunogeneous for human immunoglobulin showing specificity to protein L-selectin. EFFECT: improved method of preparing. 19 cl, 1 tbl, 6 dwg, 5 ex</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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language eng ; rus
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title HUMAN IMMUNOGLOBULIN SHOWING SPECIFICITY TO HUMAN PROTEIN L-SELECTIN
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