METHOD OF PREPARING SUBSTITUTED 2-(PHENYLAMINO)-2- IMIDAZOLINES

FIELD: chemical industry. SUBSTANCE: substituted 2-(phenylamino)-2-imidazolines of formula I: wherein R1= R2= Cl and R3= H, CH3, F, are prepared by condensation of anilines with 1-benzoylimidazolidin-2-one in phosphorus oxychloride in the presence of lithium halides or quaternary ammonium bases. Pre...

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Hauptverfasser: NIKOL'SKAJA S.K, VITVITSKAJA A.S, KARAVAN V.S, SHAVVA A.G, BELOV V.N, BOGDANOV E.G, SOKOLOV A.E, SHCHEDROVICH K.I, KATSNEL'SON E.Z
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creator NIKOL'SKAJA S.K
VITVITSKAJA A.S
KARAVAN V.S
SHAVVA A.G
BELOV V.N
BOGDANOV E.G
SOKOLOV A.E
SHCHEDROVICH K.I
KATSNEL'SON E.Z
description FIELD: chemical industry. SUBSTANCE: substituted 2-(phenylamino)-2-imidazolines of formula I: wherein R1= R2= Cl and R3= H, CH3, F, are prepared by condensation of anilines with 1-benzoylimidazolidin-2-one in phosphorus oxychloride in the presence of lithium halides or quaternary ammonium bases. Presence of lithium salts reduces reaction time up to 20-24 hours. EFFECT: high quality of the desired compounds. 6 ex
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHOD OF PREPARING SUBSTITUTED 2-(PHENYLAMINO)-2- IMIDAZOLINES
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