STRAIN ESCHERICHIA COLI XLI - BLUE/PINSR - A PRODUCER OF PREPROINSULIN

FIELD: biotechnology, medicine, endocrinology. SUBSTANCE: strain-producer of preproinsulin is obtained by transformation of the strain E. coli XLI-Blue using plasmid pInsR and cells carrying this plasmid are removed. Strain produces preproinsulin at high yield and property that ensures to obtain ins...

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Hauptverfasser: MARKIN S.S, SEMENOV M.P, NECHAEV V.N, UVAROV V.JU
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creator MARKIN S.S
SEMENOV M.P
NECHAEV V.N
UVAROV V.JU
description FIELD: biotechnology, medicine, endocrinology. SUBSTANCE: strain-producer of preproinsulin is obtained by transformation of the strain E. coli XLI-Blue using plasmid pInsR and cells carrying this plasmid are removed. Strain produces preproinsulin at high yield and property that ensures to obtain insulin by enzymatic cleavage. Invention can be used for insulin production. EFFECT: strain indicated above, increased yield of product.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title STRAIN ESCHERICHIA COLI XLI - BLUE/PINSR - A PRODUCER OF PREPROINSULIN
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