HIRUDINE DERIVATIVE AS THROMBIN INHIBITOR, RECOMBINANT DNA ENCODING HIRUDINE DERIVATIVE AND A METHOD OF ITS PREPARING
FIELD: biotechnology. SUBSTANCE: invention relates to preparing derivative of hirudine that acts as a thrombin inhibitor and exhibiting specific activity 10 000 AT U/mg, not less. Amino acid sequence of this derivative of hirudine is identified. Also, nucleotide sequence of recombinant DNA encoding...
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