METHOD OF PREPARING THE ANTIPROCOAGULATING PREPARATION FROM MEDICINAL LEECH

METHOD OF PREPARING THE ANTIPROCOAGULATING PREPARATION FROM MEDICINAL LEECH

FIELD: medicine, bioactive substances. SUBSTANCE: method involves leeches freezing, lyophilization and the following milling, dilution with water, acidification to pH = 5.8-7.0, heating on boiling water bath for 3-15 min followed by filtrate collection. Preparation shows antithrombic activity, prolo...

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Hauptverfasser: SELEZNEV KONSTANTIN GEORGIEVICH, TITOVA ELENA ALEKSANDROVNA, NIKONOV GENNADIJ IVANOVICH
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:FIELD: medicine, bioactive substances. SUBSTANCE: method involves leeches freezing, lyophilization and the following milling, dilution with water, acidification to pH = 5.8-7.0, heating on boiling water bath for 3-15 min followed by filtrate collection. Preparation shows antithrombic activity, prolongs plasma recalcification time, inhibits aggregation and adhesion of platelets due to the presence of leech prostaglandins. EFFECT: improved method of preparing, enhanced effectiveness. 1 tble